|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
notch1
|
|
laevis
|
NF stage 40
|
midbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
notch1
|
|
laevis
|
NF stage 45
|
hindbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
htr2b
|
|
laevis
|
NF stage 40
|
midbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
htr2b
|
|
laevis
|
NF stage 45
|
diencephalon
,
hindbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
ccnd1
|
|
laevis
|
NF stage 40
|
midbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
ccnd1
|
|
laevis
|
NF stage 45
|
hindbrain
,
ventricular zone
,
central nervous system
,
proliferative region
|
|
|
Fig. 3. Expression pattern of 5-HT2B and 2C receptor mRNAs in the larval brain. The probes used are indicated at bottom of each panel. The figure shows transversal sections of larvae neural tube at stage 40 (A–C) and 45 (D–O). Panels correspond to diencephalon (D–F), mesencephalon (A–C, G–I); anterior (J–L and O) and posterior rhomboencephalon (M–N). Proliferating zones are evidenced by BrdU incorporation (E,H,K) and by labelling with proliferation markers (B,C,N,O). (E,H,K): in blue, Hoechst nuclear staining; BrdU incorporation is viewed as orange fluorescence. |
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
notch1
|
|
laevis
|
NF stage 40
|
retina
,
ciliary marginal zone
,
eye
|
notch1
|
|
laevis
|
NF stage 45
|
retina
,
ciliary marginal zone
,
eye
|
htr2b
|
|
laevis
|
NF stage 40
|
lens
,
retina
,
ciliary marginal zone
,
eye
|
htr2b
|
|
laevis
|
NF stage 45
|
retina
,
ciliary marginal zone
,
eye
,
retinal inner nuclear layer
|
ccnd1
|
|
laevis
|
NF stage 40
|
retina
,
ciliary marginal zone
,
eye
|
ccnd1
|
|
laevis
|
NF stage 45
|
retina
,
ciliary marginal zone
,
eye
|
|
|
Fig. 4. Expression of 5-HT2B and 2C receptor mRNAs in developing retina. Transverse sections through the eye of a stage 40 (A–C) and 45 larva (D–I). The probes used are indicated at bottom of each panel. The CMZ is labelled by proliferation markers (B,C,E,F) and stained with anti-BrdU antibody after BrdU incorporation (H). In blue, Hoechst nuclear staining; orange, BrdU incorporation. (G) is an enlargement of (D) to show the scattered postmitotic cells expressing 5-HT2B transcripts in the INL. CMZ, ciliary marginal zone; L, lens; INL, inner nuclear layer. |