||Fig. 1. Expression of stromelysin-3 (ST3) in the pancreas during metamorphosis. A) ST3 mRNA was measured during spontaneous and induced metamorphosis in Xenopus laevis. ST-
3 mRNA is undetectable during pre and pro-metamorphic period as well as in the adult pancreas. However ST3 expression is induced at the climax of metamorphosis (NF62) when
endogenous TH is the highest. Addition of 10 nM T3 induces ST-3 mRNA. Pro-MM is NF58; pre-MM is NF 54–55; B) Control section of an NF55 tadpole pancreas stained with ST3
antiserum; C) ST3 protein is highly up regulated in the pancreas at NF62. Scale bar=20 μm.