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nr1h5xenopus   

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Experiment details for nr1h5

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.

Gene Clone Species Stages Anatomy
nr1h5.L laevis NF stage 35 and 36 liver primordium

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  Figure 5. Prolonged FGF signaling is required for lung and liver induction. (A) Experimental design showing the time-course of FGFRi treatment. (B) Embryos treated with DMSO or FGFRi at the indicated stages were assayed at stage NF35 by in situ hybridization for markers of liver (nr1h5), lung (nkx2.1), and heart (tnni3). Representative examples are shown and the graph summarizes the % of embryos with normal, weak, or severely reduced/absent expression.