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Gene/Clone | Species | Stage | Anatomy Item | Experimenter |
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nr1h5 | xenopus |
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Experiment details for nr1h5
Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.
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Figure S1. Exogenous FGF is not sufficient to induce lung or liver lineages in explants. (A) Foregut explants with or without mesoderm were cultured from stage NF18 to NF35 in BSA or FGF2 and analyzed for expression of liver (nr1h5), lung (nkx2.1) and pancreas (pdx1) markers. (B) Western blot analysis of explants shows an increase in pErk levels upon FGF2 treatment. ( |