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nr1h5xenopus   

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Experiment details for nr1h5

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.

Prolonged FGF signaling is necessary for lung and liver induction in Xenopus.

Gene Clone Species Stages Anatomy
nr1h5.L laevis NF stage 35 and 36 liver primordium

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  Figure S1. Exogenous FGF is not sufficient to induce lung or liver lineages in explants. (A) Foregut explants with or without mesoderm were cultured from stage NF18 to NF35 in BSA or FGF2 and analyzed for expression of liver (nr1h5), lung (nkx2.1) and pancreas (pdx1) markers. (B) Western blot analysis of explants shows an increase in pErk levels upon FGF2 treatment. (