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nrxn3xenopus eye 

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Experiment details for nrxn3

The expression and alternative splicing of alpha-neurexins during Xenopus development.

The expression and alternative splicing of alpha-neurexins during Xenopus development.

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Gene Clone Species Stages Anatomy
nrxn3.L laevis NF stage 24 eye

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  Fig. 5 (Left). Nrxn III α is expressed in a subset of neural cells. (A,B) In situ hybridisation with an α-nrxn III-specific probe identifies a row of primary neurons at stage 24 (A), that lies either side of the midline towards the anterior end of the embryo. (C) By the tailbud stage, expression resolves into two stripes either side of the midline (red and green arrows). Those arrowed in red are located in the position expected for primary interneurons. The second band is located more ventrally. Within the head there are discrete areas of expression (yellow arrows). (D,E) Transverse sections at the level of the hindbrain (D) and anterior spinal cord (E). nrxnIIIα expression (red arrows) is restricted to the lateral neural tube.

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Gene Clone Species Stages Anatomy
nrxn3.L laevis NF stage 32 eye

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  Fig.4. Expression of α-neurexins is predominantly in neural tissue in the tailbud embryo. (A,B) In situ hybridisation with a nrxn Iα probe showing whole embryo (A) and an anterior neural section (B). Nrxn I is found in cells along the length of the CNS but with a distinct gap at the midbrain-hindbrain boundary. Sections show expression in the dorsolateral neural tube and within the eye. (C,D) Embryos hybridised with a nrxn IIα-specific probe show a similar pattern of staining to that seen with nrxn I. (E,F) Embryos hybridised with a nrxn IIIα-specific probe show much more restricted expression in the CNS and in section show ventrolateral and eye expression in the anterior CNS (arrows).