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tet2xenopus   

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Experiment details for tet2

Zhang Z et al. (2017) Assay

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells.

Gene Clone Species Stages Anatomy
tet2.L laevis NF stage 15 to NF stage 20
tet2.L laevis NF stage 26 to NF stage 32 brain , forebrain , midbrain , midbrain-hindbrain boundary , eye , [+]

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  FIGUTRE 8. Genes repressing or being downregulated during cancer development/progression show varied expression patterns in Xenopus embryos. A, spatial expression patterns were examined with WMISH. Embryos at the same stages as shown in Fig. 6 were used and presented in the same way as in Fig. 6. A, anterior; ad, adenohypophysial placode; ba, branchial arch; cg, cement gland; cgp, cement gland primordium; ep, epidermis; ev, ear vesicle; ey, eye; fb, forebrain; hb, hindbrain; le, lens; mb, midbrain; mhb, midbrain-hindbrain boundary; nc, notochord; nu, neuron; np, neural plate; nt, neural tube; P, posterior; pn, pronephros; pm, paraxial mesoderm; ps, posterior somite; sm, somite; tg, trigeminal nerve. B, summary of the relatedness of gene expression/function in cancer and their expression.