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Figure S1. Spatial expression pattern of kindlin2 in Xenopus laevis embryos.
(A-B) Kindlin2 was expressed in the animal pole during cleavage and blastula stages. (C-E) At the mid-gastrula stage, kindlin2 was ubiquitously expressed in the whole embryo except for the blastopore (C,D). The signals were then enriched on the dorsal side at later gastrulation (E). (F-G) At the mid-neurula stage, stronger signals appeared in neural plate and adjacent region including the neural crest. (H-I) The expression of kindlin2 was restricted and maintained in the head, cranial neural crest streams, and somites at tailbud stages. (A'-I') Sense controls, embryos were hybridized with the sense probe of kindlin2. A, B, D, A', B' and D', lateral view; C and C', vegetal view; E, F, E' and F', dorsal view; G-I and G'-I', lateral view with head towards left. |
