|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
myc
|
|
laevis
|
NF stage 24
to
NF stage 25
|
mandibular crest
,
hyoid crest
,
branchial crest
,
optic vesicle
,
cranial neural crest
,
[+]
|
myc
|
|
laevis
|
NF stage 13
to
NF stage 14
|
cement gland primordium
,
circumblastoporal collar
,
cranial neural crest
|
myc
|
|
laevis
|
NF stage 11
|
animal hemisphere
,
blastocoel roof
,
animal pole
|
myc
|
|
laevis
|
NF stage 29 and 30
|
pancreas
,
foregut
|
|
|
Fig. 6. Developmental expression pattern of the c-myc gene. A: Anterior view of an early neurula stage embryo showing c-myc expression in the cranial neural crest (arrowheads) and future cement gland (arrow). B: Posterior view of the same embryo shown in (A). Note strong expression in the cells immediately surrounding the newly closed blasto- pore. C: Lateral view of an early tailbud stage embryo showing c-myc staining in the neural crest entering the posterior pharyngeal arches (arrows), as well as in the eye (arrowhead) and the brain (white arrowhead). D: Lateral view of a mid tailbud stage embryo. c-myc expression is retained in the pharyngeal arches, most strongly in arch 2 (short arrow). Other domains of expression include the eye (long arrow), floor of the pharynx (small arrowhead), and cells of the first pharyngeal arch (large arrowhead). E: Lateral view of a tadpole stage embryo. Note expression in the pancreatic anlage (arrow), as well as in cells adjacent to the liver (arrowhead). F: Sagital section through a gastrula stage embryo stained for c-myc. Expression is strongest in the animal pole (arrowhead). G: Cross-section through an early neurula stage embryo. c-myc expres- sion is strongest in the intermediate mesoderm (large arrowhead) and the embryonic ectoderm (arrow). Paraxial mesoderm is also weakly positive (small arrowhead). H: Cross-section of a mid tailbud embryo. The future liver is positive for the c-myc gene. I: Cross-section of a mid tailbud stage embryo. c-myc expression is strong in the peripheral optic cup (arrow- head) and dorsal brain (arrow). J: Cross-section of a mid tailbud stage embryo. Note expression in dorsal somite (arrowhead), as well as in the dorsal gut (arrow). |