|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
prdx1
|
|
laevis
|
NF stage 27
to
NF stage 28
|
otic vesicle
,
brain
,
midbrain
,
hindbrain
,
eye
,
[+]
|
prdx1
|
|
laevis
|
NF stage 33 and 34
|
otic vesicle
,
lens
,
brain
,
forebrain
,
hindbrain
,
[+]
head region
,
pharyngeal arch
,
liver
,
eye
,
early proximal tubule
,
dorsal
,
anterior neural tube
,
lateral plate mesoderm
,
pronephric kidney
,
anterior dorsal lateral plate region
,
lens epithelium
|
prdx2
|
|
laevis
|
NF stage 27
to
NF stage 28
|
otic vesicle
,
head region
,
pharyngeal arch
,
tail bud
,
eye
,
[+]
|
prdx2
|
|
laevis
|
NF stage 33 and 34
|
brain
,
hindbrain
,
head region
,
somite
,
ventral blood island
,
[+]
|
prdx6
|
|
laevis
|
NF stage 27
to
NF stage 28
|
neuroectoderm
,
head mesoderm
,
somite
,
eye
,
paraxial mesoderm
|
prdx3
|
|
laevis
|
NF stage 27
to
NF stage 28
|
otic vesicle
,
brain
,
hindbrain
,
head region
,
presomitic mesoderm
,
[+]
|
prdx3
|
|
laevis
|
NF stage 33 and 34
|
otic vesicle
,
brain
,
midbrain
,
hindbrain
,
head region
,
[+]
presomitic mesoderm
,
somite
,
pronephric duct
,
ventral blood island
,
pharyngeal arch
,
mandibular arch
,
hyoid arch
,
branchial arch
,
eye
,
early proximal tubule
,
lateral plate mesoderm
,
pronephric kidney
,
anterior dorsal lateral plate region
|
prdx5
|
|
laevis
|
NF stage 27
to
NF stage 28
|
otic vesicle
,
brain
,
hindbrain
,
presomitic mesoderm
,
somite
,
[+]
|
prdx5
|
|
laevis
|
NF stage 33 and 34
|
otic vesicle
,
brain
,
hindbrain
,
somite
,
pronephric duct
,
[+]
|
|
|
laevis
|
NF stage 27
to
NF stage 28
|
otic vesicle
,
brain
,
forebrain
,
hindbrain
,
cement gland
,
[+]
|
|
|
laevis
|
NF stage 27
to
NF stage 28
|
brain
,
hindbrain
,
head region
,
mesoderm
,
somite
,
[+]
|
|
|
Fig. 2. Expression profiles of X. laevis prdx mRNA during stages 27/28 and 33/34 of embryonic development. Whole mount in situ hybridization with antisense Digoxigenin-labeled probes against the coding regions of the X. laevis prdxs was performed to determine the spatial expression pattern of prdx1 at stages 27/28 (A-F) and 33/34 (G-L). The white lines in panel G (i, ii and iii) indicate the positions of the cuts made to give the cross-sections in Supplementary Fig. S4. (Br, brain; EY, eye; PN, pronephros; FB, forebrain; HB, hindbrain; PD, proctodeum; Li, liver; PT, proximal tubule; SM, somites; PA, pharyngeal arches; Bl, blood islands; Of, olfactory placode; DT, distal tubule; CT, connecting tubule). The horizontal line across the tails (in G) is a background artifact |
|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
prdx1
|
|
laevis
|
NF stage 35 and 36
to
NF stage 37 and 38
|
otic vesicle
,
brain
,
forebrain
,
midbrain
,
hindbrain
,
[+]
|
prdx1
|
|
laevis
|
NF stage 40
to
NF stage 41
|
brain
,
liver
,
foregut
,
pronephric kidney
|
prdx2
|
|
laevis
|
NF stage 35 and 36
to
NF stage 37 and 38
|
brain
,
forebrain
,
midbrain
,
hindbrain
,
midbrain-hindbrain boundary
,
[+]
|
prdx2
|
|
laevis
|
NF stage 40
to
NF stage 41
|
forebrain
,
foregut
,
posterior cardinal vein
,
early proximal tubule
,
blood vessel
,
[+]
|
prdx3
|
|
laevis
|
NF stage 35 and 36
to
NF stage 37 and 38
|
brain
,
head region
,
somite
,
pharyngeal arch
,
eye
,
[+]
|
prdx3
|
|
laevis
|
NF stage 40
to
NF stage 41
|
brain
,
head region
,
pharyngeal arch
,
eye
,
pronephric kidney
|
prdx5
|
|
laevis
|
NF stage 35 and 36
to
NF stage 40
|
olfactory placode
,
somite
,
pronephric duct
,
eye
,
early distal tubule
,
[+]
|
prdx5
|
|
laevis
|
NF stage 40
to
NF stage 41
|
olfactory placode
,
brain
,
head region
,
somite
,
pronephric duct
,
[+]
|
|
|
laevis
|
NF stage 35 and 36
to
NF stage 37 and 38
|
brain
,
head region
,
somite
,
pharyngeal arch
,
eye
,
[+]
|
|
|
laevis
|
NF stage 40
to
NF stage 41
|
brain
,
head region
,
somite
,
pharyngeal arch
,
eye
,
[+]
|
|
|
Fig. 3. Expression profiles of X. laevis prdx mRNA during stages 36/37 and 40/41 of embryonic development. Whole mount in situ hybridization with antisense Digoxigenin-labeled probes against the coding regions of the X. laevis prdxs was performed to determine the spatial expression pattern of prdx1 at stages 36/37 (A) and 40/41 (G). (Br, brain; PT, proximal tubule; Li, liver; PD, proctodeum; Ey, eye; Bl, blood islands; Vc, vasculature; PA, pharyngeal arches; PN, pronephros; SM, somites; Of, olfactory placode; CN, cranial nerves; DT, distal tubule; CT, connecting tubule; TG, thyroid gland). The horizontal line across the tails is a background artifact. |