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FIG. 1. AChR accumulation at sites of muscle contact with former neuritic pathways containing substrate-bound neural agrin. (A) Muscle
cells after 1 day in culture. (B) Agrin immunofluorescence. (C) AChR fluorescence. Similarly numbered arrows in B and C point to the same
s i t.es. AChR accumulated at sites where muscle cells contacted the agrin path ways. Arrow heads point to characteristic AChR patches on muscle
cells which did not contact agrin pathways. Bar, 25;;m. |
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FIG. 2. AChR accumulation confined to the borders of the agrin pathway. (A) Muscle cells after 1 day in culture. (B) Agrin immunofluorescence.
(C) AChR fluorescence. Almost all of the AChR accumulation is limited to the width of the agrin pathway. Bar, 5 .um. |