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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
dvl1
|
|
laevis
|
NF stage 20
|
neural crest
,
eye primordium
,
neural tube
,
neural fold
,
anterior branchial crest
,
[+]
|
dvl1
|
|
laevis
|
NF stage 23
|
eye
,
otic placode
,
optic vesicle
,
cranial neural crest
,
otic region
,
[+]
|
dvl3
|
|
laevis
|
NF stage 18
|
paraxial mesoderm
|
dvl3
|
|
laevis
|
NF stage 23
|
presomitic mesoderm
,
paraxial mesoderm
|
dvl3
|
|
laevis
|
NF stage 35 and 36
|
otic vesicle
,
midbrain
,
hindbrain
,
somite
,
heart
,
[+]
|
dvl2
|
|
laevis
|
NF stage 22
|
eye
,
optic vesicle
,
cranial neural crest
,
neural fold
,
anterior branchial crest
,
[+]
|
dvl2
|
|
laevis
|
NF stage 23
|
forebrain
,
neural crest
,
eye
,
otic placode
,
optic vesicle
,
[+]
|
dvl2
|
|
laevis
|
NF stage 29 and 30
|
otic vesicle
,
forebrain
,
midbrain
,
hindbrain
,
somite
,
[+]
|
|
|
Figure 2. Divergent expression patterns of Dvl1, Dvl2, and Dvl3 in Xenopus embryos. A: Dorsal view of a stage-20 embryo exhibits Dvl1 expression in neural crest, optic placodes, and neural folds. B: Lateral view of a stage-23 embryo shows continued Dvl1 expression in the streaming cranial neural crest and the developing eye, as well as the otic placodes and the segmenting somites. C: Lateral view of a stage-29/30 embryo expressing Dvl1 in the somites and in multiple cranial placodes (see Supp. Fig. 2). D: Dorsal view of a stage-22 embryo exhibiting Dvl2 expression in the streaming cranial neural crest, developing eyes, and neural folds. E: Lateral view of a stage-23 embryo expressing Dvl2 in the otic placodes, neural crest, and eyes. F: Lateral view of a stage-29/30 embryo exhibits Dvl2 staining in the somites, developing eye, and branchial arches. G: Lateral view of a stage-18 embryo expressing Dvl3 in paraxial mesoderm. H: Lateral view of a stage-23 embryo exhibits Dvl3 expression in the presomitic mesoderm and developing somitomeres. I: Lateral view of a stage-35/36 embryo expressing Dvl3 in mature somites, multiple head placodes, and the developing heart. |