|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
hoxc6
|
|
laevis
|
NF stage 12
|
neuroectoderm
,
dorsal marginal zone
,
non-involuting marginal zone
|
hoxc6
|
|
laevis
|
NF stage 12.5
|
neuroectoderm
,
marginal zone
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
[+]
|
hoxc6
|
|
laevis
|
NF stage 26
|
spinal cord
,
presomitic mesoderm
,
pronephric duct
,
tail bud
,
trunk
,
[+]
|
hoxd1
|
|
laevis
|
NF stage 11
|
neuroectoderm
,
dorsal marginal zone
,
involuting marginal zone
,
non-involuting marginal zone
|
hoxd1
|
|
laevis
|
NF stage 12.5
|
circumblastoporal collar
,
non-involuting marginal zone
,
posterior
|
hoxd1
|
|
laevis
|
NF stage 26
|
spinal cord
,
presomitic mesoderm
,
mandibular arch
,
branchial arch
|
hoxa7
|
|
laevis
|
NF stage 12.5
|
neuroectoderm
,
dorsal marginal zone
,
involuting marginal zone
,
upper blastopore lip
,
non-involuting marginal zone
|
hoxc9-like
|
|
laevis
|
NF stage 12.5
|
involuted dorsal mesoderm
,
involuted ventral mesoderm
|
|
|
Fig. 2. Hox expression in ventralised and dorsalised embryos. (A) Hoxc-6 in embryos ventralised with UV. WISH (vegetal views of stages 10.5 to 12.5,
lateral view of stage 26). Similar results were obtained for Hoxd-1, Hoxb-4, Hoxa-7 and Hoxb-9 (not shown). (B) Diagram showing the onset of Hox
expression (detected with WISH) in ventralised (dark blue) and control embryos (light blue). In ventralised embryos, the temporally colinear sequence is still
present. (C) Mesodermal Hox expression (WISH) in ventralised embryos. Embryos cut through dorsolateral blastopore lips in controls and the corresponding
region in ventralised embryos. Hoxd-1 at stage 11, Hoxc-6 at stage 12, Hoxa-7 at stage 12.5. The white line indicates Brachet’s cleft, separating involuted
mesoderm from overlying ectoderm. Neurectodermal Hox staining in control embryos (C, arrowheads) is missing in ventralised embryos (C’). (D) Hox
expression is absent in embryos that were dorsalised with LiCl. Dorsalised embryos (LiCl) and controls (con) at stage 12.5 (vegetal views) and stage 26
(lateral views). Results of a WISH for Hoxd-1, Hoxc-6 and Hoxb-9. Analysis of Hoxb-4 and Hoxa-7 showed similar results (not shown). Arrowheads
indicate the anterior Hox expression boundary. |