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Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
shd
|
|
laevis
|
NF stage 18
to
NF stage 22
|
neural plate
,
neural tube
|
pkdcc.2
|
|
laevis
|
NF stage 18
|
chordal neural plate
,
eye primordium
,
cardiac mesoderm
,
neural plate
|
pkdcc.2
|
|
laevis
|
NF stage 22
|
olfactory placode
,
roof plate
,
eye
,
optic vesicle
,
heart primordium
|
slc38a8
|
|
laevis
|
NF stage 18
to
NF stage 22
|
notochord
|
tmem38a
|
|
laevis
|
NF stage 18
to
NF stage 22
|
somite
|
cyp11a1
|
|
laevis
|
NF stage 18
to
NF stage 22
|
lateral plate mesoderm
|
slc12a1
|
|
laevis
|
NF stage 18
|
pre-chordal neural plate
,
chordal neural plate
,
neural crest
,
intermediate mesoderm
,
neural plate
,
[+]
|
slc12a1
|
|
laevis
|
NF stage 22
|
brain
,
spinal cord
,
neuroectoderm
,
eye
,
central nervous system
,
[+]
|
mxi1
|
|
laevis
|
NF stage 18
|
pre-chordal neural plate
,
chordal neural plate
,
eye primordium
,
neural plate
,
cranial placode
|
mxi1
|
|
laevis
|
NF stage 22
|
olfactory placode
,
brain
,
forebrain
,
midbrain
,
hindbrain
,
[+]
|
slc27a2
|
|
laevis
|
NF stage 18
|
mandibular crest
,
hyoid crest
,
branchial crest
,
cranial neural crest
,
migratory neural crest cell
|
slc27a2
|
|
laevis
|
NF stage 22
|
heart primordium
,
cranial neural crest
,
neural tube
|
nop58
|
|
laevis
|
NF stage 18
to
NF stage 22
|
neural plate
,
neural tube
|
gse1
|
|
laevis
|
NF stage 18
|
pre-chordal neural plate
,
chordal neural plate
,
eye primordium
,
neural plate
|
gse1
|
|
laevis
|
NF stage 22
|
olfactory placode
,
brain
,
forebrain
,
midbrain
,
hindbrain
,
[+]
|
nkain4
|
|
laevis
|
NF stage 18
|
chordal neural plate
|
tfcp2l1
|
|
laevis
|
NF stage 18
to
NF stage 22
|
epidermis
,
epidermis inner layer
,
non-neural ectoderm
|
tll2
|
|
laevis
|
NF stage 18
|
cement gland primordium
,
neural plate
,
neural fold
,
neural plate border
|
tll2
|
|
laevis
|
NF stage 22
|
roof plate
,
cement gland primordium
,
posterior neural tube
,
neural tube
|
tmem150c
|
|
tropicalis
|
NF stage 18
to
NF stage 22
|
neural tube
|
1a11
|
|
laevis
|
NF stage 18
|
lateral plate mesoderm
|
1a11
|
|
laevis
|
NF stage 22
|
mesoderm
,
paraxial mesoderm
|
|
|
Figure 4. Expression patterns of selected retinoic acid receptor (RAR) target genes. Expression pattern of selected upregulated genes at stage 18 and stage 22 were determined by whole-mount in situ hybridization. Embryos were hybridized with probes made from indicated expressed sequence tag (EST) clones. The staining patterns in whole and sectioned embryos were summarized and used to categorize the genes broadly into four groups (group 1, 2, 3, and 4) by expression patterns. The signature staining of group 1 is present in the neural tube, neural crest, and optic anlagen; the staining patterns of group 2 are similar to those of group 1 but absent from the neural crest. Group 3 genes show staining in the neural tube but not in the optic anlagen. Group 4 genes have staining in the lateral plate mesoderm where RALDH2 is predominantly expressed. A, B, and C are in group 1; D, E, and F are in group 2; G, H, and I are in group 3; and J, K, and L are in group 4. A1-L1, A3-L3, M1-R1, and M2-R2: dorsal view; A2-I2 and A4-I4: anterior view; C6 and J2-L2: lateral view; C7: ventral view; C5: J4-L4 and M3-R3: sagittal section of stage 22 embryos. VLCS, very-long-chain acyl-CoA synthetase; Hypothetical, similar to ESTs from other organisms; Unidentified, no significant similarity to database sequences from any organism; Sm, somites; rp, roof plate of the neural tube; no, notochord; nt, the neural tube. |
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nkain4 (Na+/K+ transporting ATPase interacting 4) gene expression in Xenopus laevis embryo, assayed via in situ hybridization, NF stage 22, anterior view, dorsal up. |