|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
pdik1l
|
|
laevis
|
NF stage 32
|
lens
,
retina
,
pharyngeal arch
,
eye
|
nipsnap1
|
|
laevis
|
NF stage 29 and 30
|
lens
,
retina
,
mesoderm
|
nipsnap1
|
|
laevis
|
NF stage 32
|
lens
,
retina
,
pronephric duct
,
pharyngeal arch
,
eye
,
[+]
|
nipsnap1
|
|
laevis
|
NF stage 35 and 36
|
otic vesicle
,
lens
,
retina
,
pronephric duct
,
eye
,
[+]
|
taf1b
|
|
laevis
|
NF stage 32
|
olfactory placode
,
otic vesicle
,
lens
,
somite
,
pharyngeal arch
,
[+]
|
dvl2
|
|
laevis
|
NF stage 32
|
otic vesicle
,
somite
,
pharyngeal arch
,
eye
,
head
|
|
|
Figure 6. Expression of selected transdifferentiation genes during development. In situ hybridisation of five regeneration associated genes (RAG). Dark blue staining marks expression, and a white arrow indicates the position of the lens. A) Nipsnap1 expression appears in lens cells at stage 30 (A) and is also found in the pronephros (pn) and branchial arches (ba) from stage 32 (B). At stage 36, Nipsnap1 expression is seen in the pronephros and pronephritic duct (pnd) and otic vesicle (ov) as well as in the periphery of the lens (C). D) Tbp1b is expressed predominantly in lens, otic vesicle and branchial arches at stage 32. E) Tcf7 is expressed in lens and choroid fissure of the retina (cf), the midbrain-hindbrain junction (m/h), cement gland (cg), otic vesicle and pronephritic duct at at stage 32. F) Pdik1l is expressed in the developing lens and retina (re) and branchial arches at stage 32. G) Dvl2 is expressed in eye tissues but is not specific, with expression extending throughout the embryo including the somites (s), otic vesicle and branchial arches. Embryos are oriented with anterior to the left and dorsal uppermost. |