Chahine M , Sirois J , Marcotte P , Chen L , Kallen RG .

AR41,762 NIAMS NIH HHS

Backx, Molecular localization of an ion-binding site within the pore of mammalian sodium channels. 1992, Pubmed

Backx, Molecular localization of an ion-binding site within the pore of mammalian sodium channels. 1992, Pubmed
Becker, Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates. 1992, Pubmed
Catterall, Cellular and molecular biology of voltage-gated sodium channels. 1992, Pubmed
Chahine, Lidocaine block of human heart sodium channels expressed in Xenopus oocytes. 1992, Pubmed , Xenbase
Chahine, Functional expression and properties of the human skeletal muscle sodium channel. 1994, Pubmed , Xenbase
Chahine, Electrophysiological characteristics of cloned skeletal and cardiac muscle sodium channels. 1996, Pubmed , Xenbase
Chahine, Characterizing the mu-conotoxin binding site on voltage-sensitive sodium channels with toxin analogs and channel mutations. 1995, Pubmed , Xenbase
Chen, Chimeric study of sodium channels from rat skeletal and cardiac muscle. 1992, Pubmed , Xenbase
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Dudley, Modification of cardiac sodium channels by carboxyl reagents. Trimethyloxonium and water-soluble carbodiimide. 1993, Pubmed
Dudley, A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule. 1995, Pubmed
Ellinor, Structural determinants of the blockade of N-type calcium channels by a peptide neurotoxin. 1994, Pubmed , Xenbase
French, Interactions between a pore-blocking peptide and the voltage sensor of the sodium channel: an electrostatic approach to channel geometry. 1996, Pubmed
Frohnwieser, Modulation of the human cardiac sodium channel alpha-subunit by cAMP-dependent protein kinase and the responsible sequence domain. 1997, Pubmed , Xenbase
Gellens, Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel. 1992, Pubmed , Xenbase
Goldstein, The charybdotoxin receptor of a Shaker K+ channel: peptide and channel residues mediating molecular recognition. 1994, Pubmed , Xenbase
Heinemann, Calcium channel characteristics conferred on the sodium channel by single mutations. 1992, Pubmed , Xenbase
Hidaka, Disulfide pairings in geographutoxin I, a peptide neurotoxin from Conus geographus. 1990, Pubmed
Kallen, Structure, function and expression of voltage-dependent sodium channels. 1993, Pubmed
Lancelin, Tertiary structure of conotoxin GIIIA in aqueous solution. 1991, Pubmed
Li, Pore residues critical for mu-CTX binding to rat skeletal muscle Na+ channels revealed by cysteine mutagenesis. 1997, Pubmed , Xenbase
Miller, The charybdotoxin family of K+ channel-blocking peptides. 1995, Pubmed
Moczydlowski, Discrimination of muscle and neuronal Na-channel subtypes by binding competition between [3H]saxitoxin and mu-conotoxins. 1986, Pubmed
Noda, A single point mutation confers tetrodotoxin and saxitoxin insensitivity on the sodium channel II. 1989, Pubmed , Xenbase
Ohizumi, Geographutoxin II, a novel peptide inhibitor of Na channels of skeletal muscles and autonomic nerves. 1986, Pubmed
Pérez-García, Structure of the sodium channel pore revealed by serial cysteine mutagenesis. 1996, Pubmed , Xenbase
Satin, The cloned cardiac Na channel alpha-subunit expressed in Xenopus oocytes show gating and blocking properties of native channels. 1992, Pubmed , Xenbase
Sato, Active site of mu-conotoxin GIIIA, a peptide blocker of muscle sodium channels. 1991, Pubmed
Stephan, The microI skeletal muscle sodium channel: mutation E403Q eliminates sensitivity to tetrodotoxin but not to mu-conotoxins GIIIA and GIIIB. 1994, Pubmed , Xenbase
Stühmer, Structural parts involved in activation and inactivation of the sodium channel. 1989, Pubmed , Xenbase
Terlau, Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II. 1991, Pubmed , Xenbase
Trimmer, Primary structure and functional expression of a mammalian skeletal muscle sodium channel. 1989, Pubmed , Xenbase
Tsushima, Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore. 1997, Pubmed , Xenbase
White, SkM2, a Na+ channel cDNA clone from denervated skeletal muscle, encodes a tetrodotoxin-insensitive Na+ channel. 1991, Pubmed , Xenbase
Worley, Trimethyloxonium modification of single batrachotoxin-activated sodium channels in planar bilayers. Changes in unit conductance and in block by saxitoxin and calcium. 1986, Pubmed
Yanagawa, Mu-conotoxins share a common binding site with tetrodotoxin/saxitoxin on eel electroplax Na channels. 1987, Pubmed