Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-16826
Eur J Immunol 1997 Mar 01;273:763-71.
Show Gene links Show Anatomy links

The T cell receptor beta genes of Xenopus.

Chretien I , Marcuz A , Fellah J , Charlemagne J , Du Pasquier L .


???displayArticle.abstract???
cDNA of the T cell receptor beta (TCRB) have been isolated from the anuran amphibian Xenopus and they show strong structural homology to TCRB sequences of other vertebrates. Ten BV families, two D segments, ten J segments, and a single C region have been defined so far. Each V family consists of one to two members per haploid genome. A unique feature of the Xenopus TCRB constant region is the lack of N-linked carbohydrate glycosylation sites. The recombination signal sequences suggest that the mechanism of rearrangements are identical to those of mammals. The locus is inherited in a diploid manner despite the pseudotetraploidy of the Xenopus laevis and X. gilli used in this study.

???displayArticle.pubmedLink??? 9079820
???displayArticle.link??? Eur J Immunol