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Dev Biol October 30, 1995; 697 (1-2): 241-6.
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Cloning and embryonic expression of Xenopus laevis GAP-43 (XGAP-43).

Shain DH , Haile DT , Verrastro TA , Zuber MX .

Xenopus laevis GAP-43 (XGAP-43) is highly related to other vertebrate GAP-43 proteins in its N-terminal region which contains a membrane-targeting sequence, serine phosphorylation site, and calmodulin binding domain. Unlike other species examined, however, there appear to be two GAP-43-class genes in X. laevis which resulted from the genome duplication in Xenopus approximately 30 million years ago. During embryogenesis, XGAP-43 is expressed in a complex spatiotemporal pattern that is consistent with its putative role in neuronal growth and development.

PubMed ID: 8593582
Article link: Dev Biol
Grant support: [+]

Species referenced: Xenopus laevis
Genes referenced: arfgap3 gap43

Article Images: [+] show captions