Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-19121
Dev Biol October 30, 1995; 697 (1-2): 241-6.
Show Gene links Show Anatomy links

Cloning and embryonic expression of Xenopus laevis GAP-43 (XGAP-43).

Shain DH , Haile DT , Verrastro TA , Zuber MX .


Abstract
Xenopus laevis GAP-43 (XGAP-43) is highly related to other vertebrate GAP-43 proteins in its N-terminal region which contains a membrane-targeting sequence, serine phosphorylation site, and calmodulin binding domain. Unlike other species examined, however, there appear to be two GAP-43-class genes in X. laevis which resulted from the genome duplication in Xenopus approximately 30 million years ago. During embryogenesis, XGAP-43 is expressed in a complex spatiotemporal pattern that is consistent with its putative role in neuronal growth and development.

PubMed ID: 8593582
Article link: Dev Biol
Grant support: [+]

Species referenced: Xenopus laevis
Genes referenced: arfgap3 gap43


Article Images: [+] show captions