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Nature 1988 Oct 06;3356190:519-25. doi: 10.1038/335519a0.
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Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes.

Sagata N , Oskarsson M , Copeland T , Brumbaugh J , Vande Woude GF .

The c-mos proto-oncogene is expressed as a maternal mRNA in oocytes and early embryos of Xenopus laevis, but its translation product pp39mos is detectable only during progesterone-induced oocyte maturation. Microinjection of mos-specific antisense oligonucleotides into oocytes not only prevents expression of pp39mos, but also blocks germinal vesicle breakdown, indicating that it functions during reinitiation of meiotic division.

PubMed ID: 2971141
Article link: Nature

Species referenced: Xenopus laevis
Genes referenced: mos