XB-ART-30456Boll Soc Ital Biol Sper December 15, 1982; 58 (23): 1535-40.
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A satisfactory purification from Xenopus laevis epidermis is presented. Ki and Kd values for the ouabain-enzyme interaction have been evaluated. Both parameters appear very low, as compared with those demonstrated in other anurans. Very low digitalis-like compound level was demonstrated in Xenopus; on the contrary in Bufo, in which these substances play a defensive role, it is very high. Our results strengthen the hypothesis of a physiological action of such compounds in regulating enzyme-driven Na+/K+ exchanges.
PubMed ID: 6299312
Species referenced: Xenopus laevis
Genes referenced: atp1a1