Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
Biochim Biophys Acta August 1, 2012; 1818 (8): 1952-61.
Show Gene links Show Anatomy links

Connexins in epidermal homeostasis and skin disease.

Scott CA , Tattersall D , O'Toole EA , Kelsell DP .

The expression of multiple connexin (Cx) types in the epidermis, their differential expression during wound closure and the association of skin pathology with specific Cx gene mutations, are indicative of important functions for Cxs in the skin. In this review, we focus on the role of Cx proteins in the epidermis and during wound healing and discuss mutations in Cx genes which cause skin disease. This article is part of a Special Issue entitled: The Communicating junctions, composition, structure and characteristics.

PubMed ID: 21933662
Article link: Biochim Biophys Acta

Species referenced: Xenopus
Genes referenced: gja1 gjb2 gjb3 gjb4
GO keywords: wound healing [+]

Disease Ontology terms: Bart-Pumphrey syndrome [+]