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XB-ART-47501
Dev Cell 2012 Dec 11;236:1121-2. doi: 10.1016/j.devcel.2012.11.011.
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Making limbs from fins.

Schneider I , Shubin NH .


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Our limbs evolved from fish fins as vertebrates colonized aquatic shallows and land. If we understood the genetics underlying this transition, could we build a limb on a fish? In this issue of Developmental Cell, Freitas et al. (2012) show that boosting Hoxd13 expression can bring zebrafish one step closer to terra firma.

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Species referenced: Xenopus
Genes referenced: hoxd13 tbx2


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References :
Freitas, Hoxd13 contribution to the evolution of vertebrate appendages. 2012, Pubmed