Stith BJ .

R15 HD052546 NICHD NIH HHS , R15 HD065661 NICHD NIH HHS , R15HD052546 NICHD NIH HHS , R15HD065661 NICHD NIH HHS , R15 GM122036 NIGMS NIH HHS

Ahn, Transmodulation between phospholipase D and c-Src enhances cell proliferation. 2003, Pubmed

Ahn, Transmodulation between phospholipase D and c-Src enhances cell proliferation. 2003, Pubmed
Ajmat, Role of phospholipase A2 pathway in regulating activation of Bufo arenarum oocytes. 2013, Pubmed
Amata, Multi-phosphorylation of the intrinsically disordered unique domain of c-Src studied by in-cell and real-time NMR spectroscopy. 2013, Pubmed , Xenbase
Ammar, Lipids in Regulated Exocytosis: What are They Doing? 2013, Pubmed
Antal, Intramolecular conformational changes optimize protein kinase C signaling. 2014, Pubmed
Arcario, Membrane-induced structural rearrangement and identification of a novel membrane anchor in talin F2F3. 2014, Pubmed
Arts, Fusion of artificial membranes with mammalian spermatozoa. Specific involvement of the equatorial segment after acrosome reaction. 1993, Pubmed
Bach, ADP-ribosylation factor 6 regulates mammalian myoblast fusion through phospholipase D1 and phosphatidylinositol 4,5-bisphosphate signaling pathways. 2010, Pubmed
Bader, Phospholipase D in calcium-regulated exocytosis: lessons from chromaffin cells. 2009, Pubmed
Barona, Diacylglycerol induces fusion of nuclear envelope membrane precursor vesicles. 2005, Pubmed
Bates, Activation of Src and release of intracellular calcium by phosphatidic acid during Xenopus laevis fertilization. 2014, Pubmed , Xenbase
Bearer, Modifications of anionic-lipid domains preceding membrane fusion in guinea pig sperm. 1982, Pubmed
Belton, Isolation and characterization of sea urchin egg lipid rafts and their possible function during fertilization. 2001, Pubmed
Bement, Activators of protein kinase C trigger cortical granule exocytosis, cortical contraction, and cleavage furrow formation in Xenopus laevis oocytes and eggs. 1989, Pubmed , Xenbase
Bennet, Evidence for the activation of phospholipases during acrosome reaction of human sperm elicited by calcium ionophore A23187. 1987, Pubmed
Bhugra, Modification of intracellular free calcium in cultured A10 vascular smooth muscle cells by exogenous phosphatidic acid. 2003, Pubmed
Bianchi, Juno is the egg Izumo receptor and is essential for mammalian fertilization. 2014, Pubmed
Blackwood, Phospholipase D activity facilitates Ca2+-induced aggregation and fusion of complex liposomes. 1997, Pubmed
Blackwood, Characterization of Ca2(+)-dependent phospholipid binding, vesicle aggregation and membrane fusion by annexins. 1990, Pubmed
Bodin, Production of phosphatidylinositol 3,4,5-trisphosphate and phosphatidic acid in platelet rafts: evidence for a critical role of cholesterol-enriched domains in human platelet activation. 2001, Pubmed
Bondeson, Promotion of acid-induced membrane fusion by basic peptides. Amino acid and phospholipid specificities. 1990, Pubmed
Boonyaratanakornkit, Progesterone receptor contains a proline-rich motif that directly interacts with SH3 domains and activates c-Src family tyrosine kinases. 2001, Pubmed , Xenbase
Boulware, IP3 receptor activity is differentially regulated in endoplasmic reticulum subdomains during oocyte maturation. 2005, Pubmed , Xenbase
Breitbart, Role and regulation of EGFR in actin remodeling in sperm capacitation and the acrosome reaction. 2011, Pubmed
Breitbart, Role of actin cytoskeleton in mammalian sperm capacitation and the acrosome reaction. 2005, Pubmed
Bunney, PLC regulation: emerging pictures for molecular mechanisms. 2011, Pubmed
Burger, Dynamin is membrane-active: lipid insertion is induced by phosphoinositides and phosphatidic acid. 2000, Pubmed
Buschiazzo, Cholesterol depletion disorganizes oocyte membrane rafts altering mouse fertilization. 2013, Pubmed
Byrne, PLCgamma is enriched on poly-phosphoinositide-rich vesicles to control nuclear envelope assembly. 2007, Pubmed
Cai, Ca2+-independent binding of anionic phospholipids by phospholipase C δ1 EF-hand domain. 2013, Pubmed
Camacho, Spiral calcium waves: implications for signalling. 1995, Pubmed , Xenbase
Campanella, Ultrastructural observations on cortical endoplasmic reticulum and on residual cortical granules in the egg of Xenopus laevis. 1977, Pubmed , Xenbase
Capco, The role of protein kinase C in reorganization of the cortical cytoskeleton during the transition from oocyte to fertilization-competent egg. 1992, Pubmed , Xenbase
Chapman, How does synaptotagmin trigger neurotransmitter release? 2008, Pubmed
Charbonneau, The onset of activation responsiveness during maturation coincides with the formation of the cortical endoplasmic reticulum in oocytes of Xenopus laevis. 1984, Pubmed , Xenbase
Chasserot-Golaz, Lipid dynamics in exocytosis. 2010, Pubmed
Chiba, Development of calcium release mechanisms during starfish oocyte maturation. 1990, Pubmed
Choi, A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis. 2006, Pubmed
Cinq-Frais, A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1. 2013, Pubmed
Cockcroft, Signalling role for ARF and phospholipase D in mast cell exocytosis stimulated by crosslinking of the high affinity FcepsilonR1 receptor. 2002, Pubmed
Cockcroft, Phospholipase D: a downstream effector of ARF in granulocytes. 1994, Pubmed
Cohen, Crosstalk between protein kinase A and C regulates phospholipase D and F-actin formation during sperm capacitation. 2004, Pubmed
Dale, Is the idea of a fast block to polyspermy based on artifact? 2014, Pubmed
DeBell, Functional independence and interdependence of the Src homology domains of phospholipase C-gamma1 in B-cell receptor signal transduction. 1999, Pubmed
Dhalla, Phosphatidic acid: a potential signal transducer for cardiac hypertrophy. 1997, Pubmed
Di Fulvio, Phospholipase D2 (PLD2) shortens the time required for myeloid leukemic cell differentiation: mechanism of action. 2012, Pubmed
Domino, Activation of phospholipase D by the fucose-sulfate glycoconjugate that induces an acrosome reaction in spermatozoa. 1989, Pubmed
Du, Regulation of phospholipase D1 subcellular cycling through coordination of multiple membrane association motifs. 2003, Pubmed
Dürr, The magic of bicelles lights up membrane protein structure. 2012, Pubmed
El-Jouni, Calcium signaling differentiation during Xenopus oocyte maturation. 2005, Pubmed , Xenbase
Etkovitz, Bovine sperm acrosome reaction induced by G-protein-coupled receptor agonists is mediated by epidermal growth factor receptor transactivation. 2009, Pubmed
Exton, Regulation of phospholipase D. 2002, Pubmed
Exton, Phospholipase D-structure, regulation and function. 2002, Pubmed
Falke, Interplay between phosphoinositide lipids and calcium signals at the leading edge of chemotaxing ameboid cells. 2014, Pubmed
Farquhar, Interaction of PLD1b with actin in antigen-stimulated mast cells. 2007, Pubmed
Foster, Phospholipase D and the maintenance of phosphatidic acid levels for regulation of mammalian target of rapamycin (mTOR). 2014, Pubmed
Frohman, Role of mitochondrial lipids in guiding fission and fusion. 2015, Pubmed
Gallicano, PKC--a pivotal regulator of early development. 1997, Pubmed
Garbi, Activation of protein kinase calpha in the lysophosphatidic acid-induced bovine sperm acrosome reaction and phospholipase D1 regulation. 2000, Pubmed
Glahn, Tyrosine kinase inhibitors block sperm-induced egg activation in Xenopus laevis. 1999, Pubmed , Xenbase
Glahn, Voltage-clamp study of the activation currents and fast block to polyspermy in the egg of Xenopus laevis. 2003, Pubmed , Xenbase
Glaser, Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains. 1996, Pubmed
Gomez-Cambronero, Phospholipase D in cell signaling: from a myriad of cell functions to cancer growth and metastasis. 2014, Pubmed
Gozani, The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. 2003, Pubmed
Gresset, The phospholipase C isozymes and their regulation. 2012, Pubmed
Guo, Phosphatidic acid binds and stimulates Arabidopsis sphingosine kinases. 2011, Pubmed
Hague, The inositol (1,4,5)-trisphosphate 3-kinase of Xenopus oocyte is activated by CaMKII and involved in the regulation of InsP3-mediated Ca2+ release. 1999, Pubmed , Xenbase
Hajicek, Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes. 2013, Pubmed
Halet, The dynamics of plasma membrane PtdIns(4,5)P(2) at fertilization of mouse eggs. 2002, Pubmed
Harrison, Variation on an Src-like theme. 2003, Pubmed
Hasan, Gamete membrane microdomains and their associated molecules in fertilization signaling. 2011, Pubmed , Xenbase
Hashizume, Phosphatidic acid with medium-length fatty acyl chains synergistically stimulates phospholipase C with Ca2+ in rabbit platelets. 1992, Pubmed
Hastie, Metabolites of the phospholipase D pathway regulate H2O2-induced filamin redistribution in endothelial cells. 1998, Pubmed
Haucke, Lipids and lipid modifications in the regulation of membrane traffic. 2007, Pubmed
Holden, A dual role for diacylglycerol kinase generated phosphatidic acid in autoantibody-induced neutrophil exocytosis. 2011, Pubmed
Holland, Quantification of phosphatidic acid and lysophosphatidic acid by HPLC with evaporative light-scattering detection. 2003, Pubmed , Xenbase
Huang, Insulin-stimulated plasma membrane fusion of Glut4 glucose transporter-containing vesicles is regulated by phospholipase D1. 2005, Pubmed
Huang, piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling. 2011, Pubmed
Hughes, Phospholipase D1 regulates secretagogue-stimulated insulin release in pancreatic beta-cells. 2004, Pubmed
Imai, Evidence for tight coupling of phospholipase activation and Ca2+ influx during acrosome reaction of golden hamster spermatozoa. 1990, Pubmed
Inhorn, Pathway for inositol 1,3,4-trisphosphate and 1,4-bisphosphate metabolism. 1987, Pubmed
Itach, Hyper-activated motility in sperm capacitation is mediated by phospholipase D-dependent actin polymerization. 2012, Pubmed
Itoh, The tyrosine kinase Fer is a downstream target of the PLD-PA pathway that regulates cell migration. 2009, Pubmed
Iwao, The need of MMP-2 on the sperm surface for Xenopus fertilization: its role in a fast electrical block to polyspermy. 2014, Pubmed , Xenbase
Jackowski, Stimulation of phosphatidylinositol 4,5-bisphosphate phospholipase C activity by phosphatidic acid. 1989, Pubmed
Jacob, Characteristics of phospholipase C present in membranes of Xenopus laevis oocytes. Stimulation by phosphatidic acid. 1993, Pubmed , Xenbase
Jang, Understanding of the roles of phospholipase D and phosphatidic acid through their binding partners. 2012, Pubmed
Jang, The direct interaction of phospholipase C-gamma 1 with phospholipase D2 is important for epidermal growth factor signaling. 2003, Pubmed
Jenkins, Type I phosphatidylinositol 4-phosphate 5-kinase isoforms are specifically stimulated by phosphatidic acid. 1994, Pubmed
Jones, The regulation of phospholipase C-gamma 1 by phosphatidic acid. Assessment of kinetic parameters. 1993, Pubmed
Jung, Phosphatidic acid is important to the translocation of Rab3A from the cytosol to phospholipid membranes. 1999, Pubmed
Kajiwara, c-Src-induced activation of ceramide metabolism impairs membrane microdomains and promotes malignant progression by facilitating the translocation of c-Src to focal adhesions. 2014, Pubmed
Kashir, Sperm-induced Ca2+ release during egg activation in mammals. 2014, Pubmed
Kashir, Comparative biology of sperm factors and fertilization-induced calcium signals across the animal kingdom. 2013, Pubmed
Kawano, Lipid rafts: keys to sperm maturation, fertilization, and early embryogenesis. 2011, Pubmed
Kim, The phosphatidylinositol-transfer protein Nir2 binds phosphatidic acid and positively regulates phosphoinositide signalling. 2013, Pubmed
Kinsey, Intersecting roles of protein tyrosine kinase and calcium signaling during fertilization. 2013, Pubmed
Kline, Attributes and dynamics of the endoplasmic reticulum in mammalian eggs. 2000, Pubmed
Kline, Evidence for the involvement of a pertussis toxin-insensitive G-protein in egg activation of the frog, Xenopus laevis. 1991, Pubmed , Xenbase
Knauss, Phosphatidic acid modulates DNA synthesis, phospholipase C, and platelet-derived growth factor mRNAs in cultured mesangial cells. Role of protein kinase C. 1990, Pubmed
Kobrinsky, Ceramide triggers intracellular calcium release via the IP(3) receptor in Xenopus laevis oocytes. 1999, Pubmed , Xenbase
Kooijman, Modulation of membrane curvature by phosphatidic acid and lysophosphatidic acid. 2003, Pubmed
Kraft, Plasma membrane organization and function: moving past lipid rafts. 2013, Pubmed
Kurokawa, Evidence that activation of Src family kinase is not required for fertilization-associated [Ca2+]i oscillations in mouse eggs. 2004, Pubmed
Kurz, Phosphatidic acid stimulates inositol 1,4,5-trisphosphate production in adult cardiac myocytes. 1993, Pubmed
Lang, The trail to deadly membrane rafts. 2013, Pubmed
Larabell, A PKC wave follows the calcium wave after activation of Xenopus eggs. 2004, Pubmed , Xenbase
Lee, The roles of phospholipase D in EGFR signaling. 2009, Pubmed
Leguia, Synaptotagmin I is involved in the regulation of cortical granule exocytosis in the sea urchin. 2006, Pubmed
Liguori, Various protein kinases regulate human sperm acrosome reaction and the associated phosphorylation of Tyr residues and of the Thr-Glu-Tyr motif. 2005, Pubmed
Ling, Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature. 2014, Pubmed
Lisboa, Phospholipase d promotes lipid microdomain-associated signaling events in mast cells. 2009, Pubmed
Litosch, Regulation of phospholipase C-beta(1) activity by phosphatidic acid. 2000, Pubmed
Liu, Phosphatidic acid increases inositol-1,4,5,-trisphosphate and [Ca2+]i levels in neonatal rat cardiomyocytes. 1999, Pubmed
Liu, Phosphatidic acid-mediated signaling. 2013, Pubmed
Luria, Detergent-free domain isolated from Xenopus egg plasma membrane with properties similar to those of detergent-resistant membranes. 2002, Pubmed , Xenbase
Luzzi, The physiologic concentration of inositol 1,4,5-trisphosphate in the oocytes of Xenopus laevis. 1998, Pubmed , Xenbase
Madani, Implication of acyl chain of diacylglycerols in activation of different isoforms of protein kinase C. 2001, Pubmed
Mahbub Hasan, The egg membrane microdomain-associated uroplakin III-Src system becomes functional during oocyte maturation and is required for bidirectional gamete signaling at fertilization in Xenopus laevis. 2014, Pubmed , Xenbase
Mammadova, Evidence that phosphatidylinositol 3-kinase is involved in sperm-induced tyrosine kinase signaling in Xenopus egg fertilization. 2009, Pubmed , Xenbase
Martens, Role of C2 domain proteins during synaptic vesicle exocytosis. 2010, Pubmed
Martin, Role of PI(4,5)P(2) in vesicle exocytosis and membrane fusion. 2012, Pubmed
Massé, The lysophosphatidic acid (LPA) and sphingosine-1-phosphate (S1P) receptor gene families: cloning and comparative expression analysis in Xenopus laevis. 2010, Pubmed , Xenbase
Mazie, Epithelial cell motility is triggered by activation of the EGF receptor through phosphatidic acid signaling. 2006, Pubmed
McGhee, Effects of phosphatidic acid on parathyroid hormone release, intracellular free Ca2+, and inositol phosphates in dispersed bovine parathyroid cells. 1990, Pubmed
McGinnis, Protein tyrosine kinase signaling during oocyte maturation and fertilization. 2011, Pubmed
Meers, Annexin I interactions with human neutrophil specific granules: fusogenicity and coaggregation with plasma membrane vesicles. 1993, Pubmed
Mehlmann, SH2 domain-mediated activation of an SRC family kinase is not required to initiate Ca2+ release at fertilization in mouse eggs. 2005, Pubmed
Mendonsa, Phosphatidylinositol-4,5-bisphosphate and phospholipase D-generated phosphatidic acid specify SNARE-mediated vesicle fusion for prospore membrane formation. 2009, Pubmed
Miller, Beyond IP3: roles for higher order inositol phosphates in immune cell signaling. 2008, Pubmed
Mima, Complex lipid requirements for SNARE- and SNARE chaperone-dependent membrane fusion. 2009, Pubmed
Moolenaar, Growth factor-like action of phosphatidic acid. , Pubmed
Moore, Identification of an abl-related protein tyrosine kinase in the cortex of the sea urchin egg: possible role at fertilization. 1994, Pubmed
Morgan, ADP-ribosylation-factor-regulated phospholipase D activity localizes to secretory vesicles and mobilizes to the plasma membrane following N-formylmethionyl-leucyl-phenylalanine stimulation of human neutrophils. 1997, Pubmed
Moritz, Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase. 1992, Pubmed
Morrison, Nongenomic action of progesterone: activation of Xenopus oocyte phospholipase C through a plasma membrane-associated tyrosine kinase. 2000, Pubmed , Xenbase
Murase, Ceramide enhances acrosomal exocytosis triggered by calcium and the calcium ionophore A23187 in boar spermatozoa. 2004, Pubmed
Murayama, Phosphatidic acid may stimulate membrane receptors mediating adenylate cyclase inhibition and phospholipid breakdown in 3T3 fibroblasts. 1987, Pubmed
Nader, How to make a good egg!: The need for remodeling of oocyte Ca(2+) signaling to mediate the egg-to-embryo transition. 2013, Pubmed , Xenbase
Noguchi, Localized calcium signals along the cleavage furrow of the Xenopus egg are not involved in cytokinesis. 2002, Pubmed , Xenbase
Nomikos, Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues. 2007, Pubmed
Ohguchi, Tyrosine phosphorylation of 100-115 kDa proteins by phosphatidic acid generated via phospholipase D activation in HL60 granulocytes. 1997, Pubmed
Owen, The lipid raft hypothesis revisited--new insights on raft composition and function from super-resolution fluorescence microscopy. 2012, Pubmed
Pan, Cdk5 targets active Src for ubiquitin-dependent degradation by phosphorylating Src(S75). 2011, Pubmed
Park, Overexpression of phospholipase D enhances matrix metalloproteinase-2 expression and glioma cell invasion via protein kinase C and protein kinase A/NF-kappaB/Sp1-mediated signaling pathways. 2009, Pubmed
Parys, Isolation, characterization, and localization of the inositol 1,4,5-trisphosphate receptor protein in Xenopus laevis oocytes. 1992, Pubmed , Xenbase
Patwardhan, Myristoylation and membrane binding regulate c-Src stability and kinase activity. 2010, Pubmed
Pawelczyk, Phospholipase C-delta3 binds with high specificity to phosphatidylinositol 4,5-bisphosphate and phosphatidic acid in bilayer membranes. 1999, Pubmed
Peng, Mammalian phospholipase D physiological and pathological roles. 2012, Pubmed
Peng, An essential role for phospholipase D in the activation of protein kinase C and degranulation in mast cells. 2005, Pubmed
Petcoff, Lipid levels in sperm, eggs, and during fertilization in Xenopus laevis. 2008, Pubmed , Xenbase
Pike, Epidermal growth factor receptors are localized to lipid rafts that contain a balance of inner and outer leaflet lipids: a shotgun lipidomics study. 2005, Pubmed
Pleskot, Regulation of cytoskeletal dynamics by phospholipase D and phosphatidic acid. 2013, Pubmed
Powner, Antigen-stimulated activation of phospholipase D1b by Rac1, ARF6, and PKCalpha in RBL-2H3 cells. 2002, Pubmed
Prates, A role of lipid metabolism during cumulus-oocyte complex maturation: impact of lipid modulators to improve embryo production. 2014, Pubmed
Pérez, Lipid binding by the Unique and SH3 domains of c-Src suggests a new regulatory mechanism. 2013, Pubmed , Xenbase
Qian, Cross-talk between receptor-regulated phospholipase D and phospholipase C in brain. 1991, Pubmed
Reue, Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism. 2008, Pubmed
Riffo, Role of phospholipase A2 in mammalian sperm-egg fusion: development of hamster oolemma fusibility by lysophosphatidylcholine. 1997, Pubmed
Roach, Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization. 2012, Pubmed
Roldan, Polyphosphoinositide breakdown and subsequent exocytosis in the Ca2+/ionophore-induced acrosome reaction of mammalian spermatozoa. 1989, Pubmed
Roth, Molecular mechanisms of PLD function in membrane traffic. 2008, Pubmed
Runft, Calcium release at fertilization of Xenopus eggs requires type I IP(3) receptors, but not SH2 domain-mediated activation of PLCgamma or G(q)-mediated activation of PLCbeta. 1999, Pubmed , Xenbase
Sakakibara, Molecular identification and characterization of Xenopus egg uroplakin III, an egg raft-associated transmembrane protein that is tyrosine-phosphorylated upon fertilization. 2005, Pubmed , Xenbase
Sankarshanan, Identification of a novel lipid raft-targeting motif in Src homology 2-containing phosphatase 1. 2007, Pubmed
Sato, Low density detergent-insoluble membrane of Xenopus eggs: subcellular microdomain for tyrosine kinase signaling in fertilization. 2002, Pubmed , Xenbase
Sato, Signal transduction pathways leading to Ca2+ release in a vertebrate model system: lessons from Xenopus eggs. 2006, Pubmed , Xenbase
Sato, Phosphatidylinositol 4,5-bisphosphate stimulates phosphorylation of the adaptor protein Shc by c-Src. 1997, Pubmed
Sato, Hydrogen peroxide induces Src family tyrosine kinase-dependent activation of Xenopus eggs. 2001, Pubmed , Xenbase
Sato, Tyrosine kinase-dependent activation of phospholipase Cgamma is required for calcium transient in Xenopus egg fertilization. 2000, Pubmed , Xenbase
Sato, Reconstitution of Src-dependent phospholipase Cgamma phosphorylation and transient calcium release by using membrane rafts and cell-free extracts from Xenopus eggs. 2003, Pubmed , Xenbase
Satoh, Protein tyrosine kinase activity of eggs of the sea urchin Strongylocentrotus purpuratus: the regulation of its increase after fertilization. 1985, Pubmed
Sauro, Changes in phospholipid metabolism dependent on calcium-regulated myoblast fusion. 1988, Pubmed
Sergeant, Phosphatidic acid regulates tyrosine phosphorylating activity in human neutrophils: enhancement of Fgr activity. 2001, Pubmed
Shi, Mechanisms of MARCKS gene activation during Xenopus development. 1997, Pubmed , Xenbase
Siddiqui, Phosphatidic acid elicits calcium mobilization and actin polymerization through a tyrosine kinase-dependent process in human neutrophils: a mechanism for induction of chemotaxis. 1997, Pubmed
Siddiqui, Phosphatidylinositol 3'-kinase-mediated calcium mobilization regulates chemotaxis in phosphatidic acid-stimulated human neutrophils. 2000, Pubmed
Sigal, Amino-terminal basic residues of Src mediate membrane binding through electrostatic interaction with acidic phospholipids. 1994, Pubmed
Sims, Metabolism of inositol 1,4,5-trisphosphate and inositol 1,3,4,5-tetrakisphosphate by the oocytes of Xenopus laevis. 1998, Pubmed , Xenbase
Snow, Fertilization stimulates an increase in inositol trisphosphate and inositol lipid levels in Xenopus eggs. 1996, Pubmed , Xenbase
Spivack, Microinjection of pp60v-src into Xenopus oocytes increases phosphorylation of ribosomal protein S6 and accelerates the rate of progesterone-induced meiotic maturation. 1984, Pubmed , Xenbase
Stith, sn-1,2-diacylglycerol and choline increase after fertilization in Xenopus laevis. 1997, Pubmed , Xenbase
Stith, Insulin and progesterone increase 32PO4-labeling of phospholipids and inositol 1,4,5-trisphosphate mass in Xenopus oocytes. 1992, Pubmed , Xenbase
Stith, The effect of insulin on intracellular ph and ribosomal protein S6 phosphorylation in oocytes of Xenopus laevis. 1984, Pubmed , Xenbase
Stith, Inositol 1,4,5-trisphosphate mass changes from fertilization through first cleavage in Xenopus laevis. 1993, Pubmed , Xenbase
Stith, Protein kinase C initially inhibits the induction of meiotic cell division in Xenopus oocytes. 1992, Pubmed , Xenbase
Stith, Microinjection of inositol 1,2-(cyclic)-4,5-trisphosphate, inositol 1,3,4,5-tetrakisphosphate, and inositol 1,4,5-trisphosphate into intact Xenopus oocytes can induce membrane currents independent of extracellular calcium. 1989, Pubmed , Xenbase
Stith, Sperm increase inositol 1,4,5-trisphosphate mass in Xenopus laevis eggs preinjected with calcium buffers or heparin. 1994, Pubmed , Xenbase
Stith, Insulin-like growth factor 1, insulin, and progesterone induce early and late increases in Xenopus oocyte sn-1,2-diacylglycerol levels before meiotic cell division. 1991, Pubmed , Xenbase
Stith, Induction of meiotic maturation in Xenopus oocytes by 12-O-tetradecanoylphorbol 13-acetate. 1987, Pubmed , Xenbase
Stith, Quantification of major classes of Xenopus phospholipids by high performance liquid chromatography with evaporative light scattering detection. 2000, Pubmed , Xenbase
Stith, The antidiabetic drug metformin elevates receptor tyrosine kinase activity and inositol 1,4,5-trisphosphate mass in Xenopus oocytes. 1996, Pubmed , Xenbase
Stricker, Structural reorganizations of the endoplasmic reticulum during egg maturation and fertilization. 2006, Pubmed
Stricker, Roles of Src family kinase signaling during fertilization and the first cell cycle in the marine protostome worm Cerebratulus. 2010, Pubmed
Su, 5-Fluoro-2-indolyl des-chlorohalopemide (FIPI), a phospholipase D pharmacological inhibitor that alters cell spreading and inhibits chemotaxis. 2009, Pubmed
Summers, Polyphosphoinositide inclusion in artificial lipid bilayer vesicles promotes divalent cation-dependent membrane fusion. 1996, Pubmed
Sun, Endoplasmic reticulum remodeling tunes IP₃-dependent Ca²+ release sensitivity. 2011, Pubmed , Xenbase
Südhof, Membrane fusion: grappling with SNARE and SM proteins. 2009, Pubmed
Tappia, Depressed phosphatidic acid-induced contractile activity of failing cardiomyocytes. 2003, Pubmed
Terasaki, Changes in organization of the endoplasmic reticulum during Xenopus oocyte maturation and activation. 2001, Pubmed , Xenbase
Tian, Gamete interactions in Xenopus laevis: identification of sperm binding glycoproteins in the egg vitelline envelope. 1997, Pubmed , Xenbase
Tian, Xenopus laevis sperm receptor gp69/64 glycoprotein is a homolog of the mammalian sperm receptor ZP2. 1999, Pubmed , Xenbase
Tokmakov, Calcium signaling and meiotic exit at fertilization in Xenopus egg. 2014, Pubmed , Xenbase
Tokmakov, Src kinase induces calcium release in Xenopus egg extracts via PLCgamma and IP3-dependent mechanism. 2002, Pubmed , Xenbase
VanRenterghem, Regulation of mitogen-activated protein kinase activation by protein kinases A and C in a cell-free system. 1994, Pubmed , Xenbase
Viaud, Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics. 2014, Pubmed
Vitale, Regulated secretion in chromaffin cells: an essential role for ARF6-regulated phospholipase D in the late stages of exocytosis. 2002, Pubmed
Vitale, Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells. 2001, Pubmed
Vitale, Synthesis of fusogenic lipids through activation of phospholipase D1 by GTPases and the kinase RSK2 is required for calcium-regulated exocytosis in neuroendocrine cells. 2010, Pubmed
Wagner, A wave of IP3 production accompanies the fertilization Ca2+ wave in the egg of the frog, Xenopus laevis: theoretical and experimental support. 2004, Pubmed , Xenbase
Wakelam, Diacylglycerol--when is it an intracellular messenger? 1998, Pubmed
Wasserman, The rapid transient decrease of sn-1,2-diacylglycerol in progesterone-stimulated Xenopus laevis oocytes is the result of an ethanol artifact. 1992, Pubmed , Xenbase
Webb, Direct measurement of intracellular pH changes in Xenopus eggs at fertilization and cleavage. 1981, Pubmed , Xenbase
Wehbi, Investigating the interfacial binding of bacterial phosphatidylinositol-specific phospholipase C. 2003, Pubmed
Whitaker, Calcium at fertilization and in early development. 2006, Pubmed , Xenbase
Williger, Release of gelatinase A (matrix metalloproteinase 2) induced by photolysis of caged phosphatidic acid in HT 1080 metastatic fibrosarcoma cells. 1995, Pubmed
Xu, Mitogenic phospholipase D activity is restricted to caveolin-enriched membrane microdomains. 2000, Pubmed
Yamada, Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells. 2004, Pubmed
Yang, Mitochondria: signaling with phosphatidic acid. 2012, Pubmed
Yim, Highly polarized EGF receptor tyrosine kinase activity initiates egg activation in Xenopus. 1994, Pubmed , Xenbase
Young, Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. 2010, Pubmed
Yáñez-Mó, Tetraspanin-enriched microdomains: a functional unit in cell plasma membranes. 2009, Pubmed
Zeniou-Meyer, Phospholipase D1 production of phosphatidic acid at the plasma membrane promotes exocytosis of large dense-core granules at a late stage. 2007, Pubmed
Zhang, Mechanism of phospholipid binding by the C2A-domain of synaptotagmin I. 1998, Pubmed
Zhao, Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos. 2007, Pubmed
Zhou, Action of phosphatidylinositol-specific phospholipase Cgamma1 on soluble and micellar substrates. Separating effects on catalysis from modulation of the surface. 1999, Pubmed
de Oliveira, Intramolecular dynamics within the N-Cap-SH3-SH2 regulatory unit of the c-Abl tyrosine kinase reveal targeting to the cellular membrane. 2013, Pubmed
van den Bogaart, Phosphatidylinositol 4,5-bisphosphate increases Ca2+ affinity of synaptotagmin-1 by 40-fold. 2012, Pubmed