Lee MT , Bonneau AR , Giraldez AJ .

F32HD071697-03 NICHD NIH HHS , R01 GM081602 NIGMS NIH HHS , R01-GM103789-2 NIGMS NIH HHS , R01-GM081602-06A1 NIGMS NIH HHS , R01-GM102251-2 NIGMS NIH HHS , R01 GM103789 NIGMS NIH HHS , T32GM007499 NIGMS NIH HHS , R01 GM101108 NIGMS NIH HHS , R01-HD074078-3 NICHD NIH HHS , R01 GM102251 NIGMS NIH HHS , R01 HD074078 NICHD NIH HHS , R21-HD073768-2 NICHD NIH HHS , R01-GM101108-3 NIGMS NIH HHS

Aanes, Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. 2011, Pubmed

Aanes, Zebrafish mRNA sequencing deciphers novelties in transcriptome dynamics during maternal to zygotic transition. 2011, Pubmed
Adenot, Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos. 1997, Pubmed
Akkers, A hierarchy of H3K4me3 and H3K27me3 acquisition in spatial gene regulation in Xenopus embryos. 2009, Pubmed , Xenbase
Ali-Murthy, An essential role for zygotic expression in the pre-cellular Drosophila embryo. 2013, Pubmed
Andersen, Developmental features of DNA methylation during activation of the embryonic zebrafish genome. 2012, Pubmed
Andreu-Vieyra, MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing. 2010, Pubmed
Aoki, Acquisition of transcriptional competence in the 1-cell mouse embryo: requirement for recruitment of maternal mRNAs. 2003, Pubmed
Aoki, Regulation of transcriptional activity during the first and second cell cycles in the preimplantation mouse embryo. 1997, Pubmed
Audic, Postfertilization deadenylation of mRNAs in Xenopus laevis embryos is sufficient to cause their degradation at the blastula stage. 1997, Pubmed , Xenbase
BROWN, RNA SYNTHESIS DURING THE DEVELOPMENT OF XENOPUS LAEVIS, THE SOUTH AFRICAN CLAWED TOAD. 1964, Pubmed , Xenbase
Barckmann, Control of maternal mRNA stability in germ cells and early embryos. 2013, Pubmed
Bashirullah, Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster. 1999, Pubmed , Xenbase
Baugh, Composition and dynamics of the Caenorhabditis elegans early embryonic transcriptome. 2003, Pubmed
Bazzini, Ribosome profiling shows that miR-430 reduces translation before causing mRNA decay in zebrafish. 2012, Pubmed
Benoit, An essential role for the RNA-binding protein Smaug during the Drosophila maternal-to-zygotic transition. 2009, Pubmed
Bernstein, A bivalent chromatin structure marks key developmental genes in embryonic stem cells. 2006, Pubmed
Biedler, Identification of early zygotic genes in the yellow fever mosquito Aedes aegypti and discovery of a motif involved in early zygotic genome activation. 2012, Pubmed
Blankenship, Two new roles for the Drosophila AP patterning system in early morphogenesis. 2001, Pubmed
Blythe, beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. 2010, Pubmed , Xenbase
Bogdanovic, Temporal uncoupling of the DNA methylome and transcriptional repression during embryogenesis. 2011, Pubmed , Xenbase
Bouniol, Endogenous transcription occurs at the 1-cell stage in the mouse embryo. 1995, Pubmed
Bouvet, The deadenylation conferred by the 3' untranslated region of a developmentally controlled mRNA in Xenopus embryos is switched to polyadenylation by deletion of a short sequence element. 1994, Pubmed , Xenbase
Braude, Human gene expression first occurs between the four- and eight-cell stages of preimplantation development. 1988, Pubmed
Brown, Repression of the Drosophila fushi tarazu (ftz) segmentation gene. 1991, Pubmed
Brykczynska, Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa. 2010, Pubmed
Bultman, Maternal BRG1 regulates zygotic genome activation in the mouse. 2006, Pubmed
Burgess, The zebrafish spiel-ohne-grenzen (spg) gene encodes the POU domain protein Pou2 related to mammalian Oct4 and is essential for formation of the midbrain and hindbrain, and for pre-gastrula morphogenesis. 2002, Pubmed
Bushati, Temporal reciprocity of miRNAs and their targets during the maternal-to-zygotic transition in Drosophila. 2008, Pubmed
Bártfai, TBP2, a vertebrate-specific member of the TBP family, is required in embryonic development of zebrafish. 2004, Pubmed
Card, Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. 2008, Pubmed
Chang, A maternal store of macroH2A is removed from pronuclei prior to onset of somatic macroH2A expression in preimplantation embryos. 2005, Pubmed
Chen, A global change in RNA polymerase II pausing during the Drosophila midblastula transition. 2013, Pubmed
Chen, The developmental miRNA profiles of zebrafish as determined by small RNA cloning. 2005, Pubmed
Chen, Global regulation of mRNA translation and stability in the early Drosophila embryo by the Smaug RNA-binding protein. 2014, Pubmed
Christians, Expression of the HSP 70.1 gene, a landmark of early zygotic activity in the mouse embryo, is restricted to the first burst of transcription. 1995, Pubmed
Colgan, Cell-cycle related regulation of poly(A) polymerase by phosphorylation. 1996, Pubmed , Xenbase
Collart, Titration of four replication factors is essential for the Xenopus laevis midblastula transition. 2013, Pubmed , Xenbase
Craig, Synthesis of RNA in non-nucleate fragments of sea urchin eggs. 1970, Pubmed
Dantonel, TBP-like factor is required for embryonic RNA polymerase II transcription in C. elegans. 2000, Pubmed
Davis, Transient expression of translation initiation factor eIF-4C during the 2-cell stage of the preimplantation mouse embryo: identification by mRNA differential display and the role of DNA replication in zygotic gene activation. 1996, Pubmed
De Renzis, Unmasking activation of the zygotic genome using chromosomal deletions in the Drosophila embryo. 2007, Pubmed
Dekens, The maternal-effect gene futile cycle is essential for pronuclear congression and mitotic spindle assembly in the zebrafish zygote. 2003, Pubmed
Di Talia, Posttranslational control of Cdc25 degradation terminates Drosophila's early cell-cycle program. 2013, Pubmed
Dimitrov, Chromatin transitions during early Xenopus embryogenesis: changes in histone H4 acetylation and in linker histone type. 1993, Pubmed , Xenbase
Dobson, The unique transcriptome through day 3 of human preimplantation development. 2004, Pubmed
Dunican, xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. 2008, Pubmed , Xenbase
Duval, Stability of maternal mRNA in Xenopus embryos: role of transcription and translation. 1990, Pubmed , Xenbase
Edgar, Early transcription in Caenorhabditis elegans embryos. 1994, Pubmed
Edgar, Parameters controlling transcriptional activation during early Drosophila development. 1986, Pubmed
Edgar, Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development. 1986, Pubmed
Edgar, Zygotic degradation of two maternal Cdc25 mRNAs terminates Drosophila's early cell cycle program. 1996, Pubmed
Faast, Histone variant H2A.Z is required for early mammalian development. 2001, Pubmed
Farrell, Mechanism and regulation of Cdc25/Twine protein destruction in embryonic cell-cycle remodeling. 2013, Pubmed
Ferg, The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish. 2007, Pubmed
Foe, Studies of nuclear and cytoplasmic behaviour during the five mitotic cycles that precede gastrulation in Drosophila embryogenesis. 1983, Pubmed
Fu, Mouse oocytes and early embryos express multiple histone H1 subtypes. 2003, Pubmed
Giraldez, Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. 2006, Pubmed
Giraldez, microRNAs, the cell's Nepenthe: clearing the past during the maternal-to-zygotic transition and cellular reprogramming. 2010, Pubmed
Goddard, Control of events during early cleavage of the mouse embryo: an analysis of the '2-cell block'. 1983, Pubmed
Golbus, The effects of inhibitors of RNA synthesis (alpha-amanitin and actinomycin D) on preimplantation mouse embryogenesis. 1973, Pubmed
Guven-Ozkan, Global transcriptional repression in C. elegans germline precursors by regulated sequestration of TAF-4. 2008, Pubmed
Haberle, Two independent transcription initiation codes overlap on vertebrate core promoters. 2014, Pubmed
Hamatani, Dynamics of global gene expression changes during mouse preimplantation development. 2004, Pubmed
Hammoud, Distinctive chromatin in human sperm packages genes for embryo development. 2009, Pubmed
Harrison, Zelda binding in the early Drosophila melanogaster embryo marks regions subsequently activated at the maternal-to-zygotic transition. 2011, Pubmed
Harrison, Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes. 2010, Pubmed
Harvey, Identification of the zebrafish maternal and paternal transcriptomes. 2013, Pubmed
Heyn, The earliest transcribed zygotic genes are short, newly evolved, and different across species. 2014, Pubmed
Howe, Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation. 1995, Pubmed , Xenbase
Huntzinger, Gene silencing by microRNAs: contributions of translational repression and mRNA decay. 2011, Pubmed
Jallow, Specialized and redundant roles of TBP and a vertebrate-specific TBP paralog in embryonic gene regulation in Xenopus. 2004, Pubmed , Xenbase
Jayaramaiah Raja, Replacement by Drosophila melanogaster protamines and Mst77F of histones during chromatin condensation in late spermatids and role of sesame in the removal of these proteins from the male pronucleus. 2005, Pubmed
Jiang, Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos. 2013, Pubmed
Kaltenbach, The TBP-like factor CeTLF is required to activate RNA polymerase II transcription during C. elegans embryogenesis. 2000, Pubmed
Kane, The zebrafish epiboly mutants. 1996, Pubmed
Kane, The zebrafish midblastula transition. 1993, Pubmed
Karr, The engrailed locus of D. melanogaster provides an essential zygotic function in precellular embryos. 1985, Pubmed
Kimelman, The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle. 1987, Pubmed , Xenbase
Knowland, RNA synthesis at the two-cell stage of mouse development. 1972, Pubmed
Laubichler, Boveri's long experiment: sea urchin merogones and the establishment of the role of nuclear chromosomes in development. 2008, Pubmed
Lecuit, slam encodes a developmental regulator of polarized membrane growth during cleavage of the Drosophila embryo. 2002, Pubmed
Lee, Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition. 2013, Pubmed
Leichsenring, Pou5f1 transcription factor controls zygotic gene activation in vertebrates. 2013, Pubmed , Xenbase
Lepikhov, Differential dynamics of histone H3 methylation at positions K4 and K9 in the mouse zygote. 2004, Pubmed
Liang, The zinc-finger protein Zelda is a key activator of the early zygotic genome in Drosophila. 2008, Pubmed
Lin, Histone variant H3.3 maintains a decondensed chromatin state essential for mouse preimplantation development. 2013, Pubmed
Lindeman, Prepatterning of developmental gene expression by modified histones before zygotic genome activation. 2011, Pubmed
Lu, Coupling of zygotic transcription to mitotic control at the Drosophila mid-blastula transition. 2009, Pubmed
Lund, Deadenylation of maternal mRNAs mediated by miR-427 in Xenopus laevis embryos. 2009, Pubmed , Xenbase
Lécuyer, Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. 2007, Pubmed
Majumder, A unique role for enhancers is revealed during early mouse development. 1995, Pubmed
Martianov, RNA polymerase II transcription in murine cells lacking the TATA binding protein. 2002, Pubmed
Martínez-Salas, The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus. 1989, Pubmed
Mathavan, Transcriptome analysis of zebrafish embryogenesis using microarrays. 2005, Pubmed
Merrill, Requirements for autosomal gene activity during precellular stages of Drosophila melanogaster. 1988, Pubmed
Mhanni, Global changes in genomic methylation levels during early development of the zebrafish embryo. 2004, Pubmed
Müller, TBP is not universally required for zygotic RNA polymerase II transcription in zebrafish. 2001, Pubmed
NEMER, OLD AND NEW RNA IN THE EMBRYOGENESIS OF THE PURPLE SEA URCHIN. 1963, Pubmed
Newport, A major developmental transition in early Xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage. 1982, Pubmed , Xenbase
Newport, A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription. 1982, Pubmed , Xenbase
Nonchev, Protamine-histone replacement and DNA replication in the male mouse pronucleus. 1990, Pubmed
Okuda, B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. 2010, Pubmed , Xenbase
Onichtchouk, Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development. 2010, Pubmed
Orkin, Chromatin connections to pluripotency and cellular reprogramming. 2011, Pubmed
Oron, Cell fate regulation in early mammalian development. 2012, Pubmed
Oswald, Active demethylation of the paternal genome in the mouse zygote. 2000, Pubmed
Paillard, EDEN and EDEN-BP, a cis element and an associated factor that mediate sequence-specific mRNA deadenylation in Xenopus embryos. 1998, Pubmed , Xenbase
Paranjpe, A genome-wide survey of maternal and embryonic transcripts during Xenopus tropicalis development. 2013, Pubmed , Xenbase
Park, Inferring the choreography of parental genomes during fertilization from ultralarge-scale whole-transcriptome analysis. 2013, Pubmed
Pikó, Quantitative changes in total RNA, total poly(A), and ribosomes in early mouse embryos. 1982, Pubmed
Poccia, RNA synthesis in male pronuclei of the sea urchin. 1985, Pubmed
Posfai, Polycomb function during oogenesis is required for mouse embryonic development. 2012, Pubmed
Potok, Reprogramming the maternal zebrafish genome after fertilization to match the paternal methylation pattern. 2013, Pubmed
Prioleau, Competition between chromatin and transcription complex assembly regulates gene expression during early development. 1994, Pubmed , Xenbase
Pritchard, Activation of transcription in Drosophila embryos is a gradual process mediated by the nucleocytoplasmic ratio. 1996, Pubmed
Puschendorf, PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. 2008, Pubmed
Pérez-Montero, The embryonic linker histone H1 variant of Drosophila, dBigH1, regulates zygotic genome activation. 2013, Pubmed
Qin, Global analyses of mRNA translational control during early Drosophila embryogenesis. 2007, Pubmed
Ram, Reporter gene expression in G2 of the 1-cell mouse embryo. 1993, Pubmed
Richter, Translational control in oocyte development. 2011, Pubmed , Xenbase
Rothe, Loss of gene function through rapid mitotic cycles in the Drosophila embryo. 1992, Pubmed
Rothstein, Gene expression during preimplantation mouse development. 1992, Pubmed
Ruzov, Kaiso is a genome-wide repressor of transcription that is essential for amphibian development. 2004, Pubmed , Xenbase
Santos, Dynamic reprogramming of DNA methylation in the early mouse embryo. 2002, Pubmed
Santos, Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. 2005, Pubmed
Satija, The TAGteam motif facilitates binding of 21 sequence-specific transcription factors in the Drosophila embryo. 2012, Pubmed
Sawicki, Evidence for expression of the paternal genome in the two-cell mouse embryo. 1981, Pubmed
Schuettengruber, Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos. 2009, Pubmed
Selvig, Cytoplasmic synthesis of RNA in the sea urchin embryo. 1970, Pubmed
Semotok, Smaug recruits the CCR4/POP2/NOT deadenylase complex to trigger maternal transcript localization in the early Drosophila embryo. 2005, Pubmed
Shechter, Analysis of histones in Xenopus laevis. I. A distinct index of enriched variants and modifications exists in each cell type and is remodeled during developmental transitions. 2009, Pubmed , Xenbase
Shermoen, Progression of the cell cycle through mitosis leads to abortion of nascent transcripts. 1991, Pubmed
Shin, The SR protein SRp38 represses splicing in M phase cells. 2002, Pubmed
Simon, Mechanisms of polycomb gene silencing: knowns and unknowns. 2009, Pubmed
Sirard, Potential and limitations of bovine-specific arrays for the analysis of mRNA levels in early development: preliminary analysis using a bovine embryonic array. 2005, Pubmed
Sive, A simple subtractive hybridization technique employing photoactivatable biotin and phenol extraction. 1988, Pubmed
Skirkanich, An essential role for transcription before the MBT in Xenopus laevis. 2011, Pubmed , Xenbase
Smith, Expression of a histone H1-like protein is restricted to early Xenopus development. 1988, Pubmed , Xenbase
Smith, A unique regulatory phase of DNA methylation in the early mammalian embryo. 2012, Pubmed
Stancheva, DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos. 2002, Pubmed , Xenbase
Stancheva, Transient depletion of xDnmt1 leads to premature gene activation in Xenopus embryos. 2000, Pubmed , Xenbase
Staudt, Mutations of the Drosophila zinc finger-encoding gene vielfältig impair mitotic cell divisions and cause improper chromosome segregation. 2006, Pubmed
Stitzel, The C. elegans DYRK Kinase MBK-2 Marks Oocyte Proteins for Degradation in Response to Meiotic Maturation. 2006, Pubmed
Storfer-Glazer, Effects of chromosomal deficiencies on early cleavage patterning and terminal phenotype in Caenorhabditis elegans embryos. 1994, Pubmed
Sulston, The embryonic cell lineage of the nematode Caenorhabditis elegans. 1983, Pubmed
Sun, Expression of SRG3, a chromatin-remodelling factor, in the mouse oocyte and early preimplantation embryos. 2007, Pubmed
Sung, Number of nuclear divisions in the Drosophila blastoderm controlled by onset of zygotic transcription. 2013, Pubmed
Surdej, Developmental regulation of bicoid mRNA stability is mediated by the first 43 nucleotides of the 3' untranslated region. 1998, Pubmed
Swinburne, Intron delays and transcriptional timing during development. 2008, Pubmed
Sørensen, Safeguarding genome integrity: the checkpoint kinases ATR, CHK1 and WEE1 restrain CDK activity during normal DNA replication. 2012, Pubmed
Tadros, The maternal-to-zygotic transition: a play in two acts. 2009, Pubmed
Tadros, SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase. 2007, Pubmed
Takahashi, Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. 2006, Pubmed
Tan, RNA sequencing reveals a diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development. 2013, Pubmed , Xenbase
Tanaka, A mammalian oocyte-specific linker histone gene H1oo: homology with the genes for the oocyte-specific cleavage stage histone (cs-H1) of sea urchin and the B4/H1M histone of the frog. 2001, Pubmed
Tani, Genomic organization and embryonic expression of miR-430 in medaka (Oryzias latipes): insights into the post-transcriptional gene regulation in early development. 2010, Pubmed
Thomas, Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. 2011, Pubmed
Torres-Padilla, Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos. 2006, Pubmed
Tsurumi, STAT is an essential activator of the zygotic genome in the early Drosophila embryo. 2011, Pubmed
Vassena, Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development. 2011, Pubmed
Vastenhouw, Chromatin signature of embryonic pluripotency is established during genome activation. 2010, Pubmed
Veenstra, Distinct roles for TBP and TBP-like factor in early embryonic gene transcription in Xenopus. 2000, Pubmed , Xenbase
Veenstra, Translation of maternal TATA-binding protein mRNA potentiates basal but not activated transcription in Xenopus embryos at the midblastula transition. 1999, Pubmed , Xenbase
Voeltz, AUUUA sequences direct mRNA deadenylation uncoupled from decay during Xenopus early development. 1998, Pubmed , Xenbase
Walser, Transcript clearance during the maternal-to-zygotic transition. 2011, Pubmed
Wang, A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo. 2004, Pubmed
Wang, Transcription in pronuclei and one- to four-cell embryos drives early development in a nematode. 2014, Pubmed
Warner, In vivo and in vitro effect of alpha-amanitin on preimplantation mouse embryo RNA polymerase. 1974, Pubmed
Wei, A database of mRNA expression patterns for the sea urchin embryo. 2006, Pubmed
Whittle, The genomic distribution and function of histone variant HTZ-1 during C. elegans embryogenesis. 2008, Pubmed
Wiekowski, Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. 1993, Pubmed
Wiekowski, Regulation of gene expression in preimplantation mouse embryos: effects of the zygotic clock and the first mitosis on promoter and enhancer activities. 1991, Pubmed
Wu, Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. 2011, Pubmed
Xie, Rewirable gene regulatory networks in the preimplantation embryonic development of three mammalian species. 2010, Pubmed
Xu, Nanog-like regulates endoderm formation through the Mxtx2-Nodal pathway. 2012, Pubmed
Xue, Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing. 2013, Pubmed
Yanai, Mapping gene expression in two Xenopus species: evolutionary constraints and developmental flexibility. 2011, Pubmed , Xenbase
Yang, Beta-catenin/Tcf-regulated transcription prior to the midblastula transition. 2002, Pubmed , Xenbase
Yasuda, Temporal regulation of gene expression in the blastoderm Drosophila embryo. 1991, Pubmed
Yasuda, Temporal regulation in the early embryo: is MBT too good to be true? 1992, Pubmed , Xenbase
Young, Control of the embryonic stem cell state. 2011, Pubmed
Zalokar, Autoradiographic study of protein and RNA formation during early development of Drosophila eggs. 1976, Pubmed
Zaret, Pioneer transcription factors: establishing competence for gene expression. 2011, Pubmed
Zeng, Gene expression in mouse oocytes and preimplantation embryos: use of suppression subtractive hybridization to identify oocyte- and embryo-specific genes. 2003, Pubmed
Zhang, Canonical nucleosome organization at promoters forms during genome activation. 2014, Pubmed
Zhang, Transcriptome profiling of human pre-implantation development. 2009, Pubmed
ten Bosch, The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription. 2006, Pubmed
van der Heijden, Transmission of modified nucleosomes from the mouse male germline to the zygote and subsequent remodeling of paternal chromatin. 2006, Pubmed