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XB-ART-52377
Curr Mol Med 2016 Jan 01;167:660-667. doi: 10.2174/1566524016666160824150729.
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The Male Abnormal Gene Family 21 (Mab21) Members Regulate Eye Development.

Huang ZX , Xiang JW , Zhou L , Nie Q , Wang L , Chen ZG , Hu XH , Xiao Y , Qing WJ , Liu YF , Sun Q , Tang XC , Liu FY , Luo ZW , Liu WB , Li DW .


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The male abnormal gene family contains 3 members, named mab21l1, mab21l2 and mab21l3. Since their first discovery in C. elegans, homologues of mab21l1 and mab21l2 have been found in Drosophila, Zebrafish, Xenopus, chicken, mouse and human. A number of studies have revealed that mab21 gene family members, mab21l1 and mab21l2, play important roles in regulating eye development. Here, we review the functions of the mab genes in regulating ocular development.

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Species referenced: Xenopus
Genes referenced: mab21l1 mab21l2 mab21l3