Dorey K , Amaya E .

082450 Wellcome Trust , Wellcome Trust

Albertson, Roles for fgf8 signaling in left-right patterning of the visceral organs and craniofacial skeleton. 2005, Pubmed

Albertson, Roles for fgf8 signaling in left-right patterning of the visceral organs and craniofacial skeleton. 2005, Pubmed
Alvarez, Neural induction in whole chick embryo cultures by FGF. 1998, Pubmed , Xenbase
Amaya, Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. 1991, Pubmed , Xenbase
Amaya, FGF signalling in the early specification of mesoderm in Xenopus. 1993, Pubmed , Xenbase
Arman, Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. 1998, Pubmed
Aulehla, Wnt3a plays a major role in the segmentation clock controlling somitogenesis. 2003, Pubmed
Ayada, Sprouty4 negatively regulates protein kinase C activation by inhibiting phosphatidylinositol 4,5-biphosphate hydrolysis. 2009, Pubmed
Bayha, Retinoic acid signaling organizes endodermal organ specification along the entire antero-posterior axis. 2009, Pubmed
Beenken, The FGF family: biology, pathophysiology and therapy. 2009, Pubmed
Beiman, Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. 1996, Pubmed
Bel-Vialar, Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups. 2002, Pubmed , Xenbase
Bertrand, Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. 2003, Pubmed
Blumberg, An essential role for retinoid signaling in anteroposterior neural patterning. 1997, Pubmed , Xenbase
Boettger, FGF8 functions in the specification of the right body side of the chick. 1999, Pubmed
Bradley, Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines. , Pubmed
Branney, Characterisation of the fibroblast growth factor dependent transcriptome in early development. 2009, Pubmed , Xenbase
Buehr, Capture of authentic embryonic stem cells from rat blastocysts. 2008, Pubmed
Böttcher, Fibroblast growth factor signaling during early vertebrate development. 2005, Pubmed
Chazaud, Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. 2006, Pubmed
Chen, C/EBPalpha initiates primitive myelopoiesis in pluripotent embryonic cells. 2009, Pubmed , Xenbase
Cho, Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid. 1990, Pubmed , Xenbase
Christen, FGF-8 is associated with anteroposterior patterning and limb regeneration in Xenopus. 1997, Pubmed , Xenbase
Christen, Spatial response to fibroblast growth factor signalling in Xenopus embryos. 1999, Pubmed , Xenbase
Ciruna, Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. 1997, Pubmed
Corson, Spatial and temporal patterns of ERK signaling during mouse embryogenesis. 2003, Pubmed
Cox, Caudalization of neural fate by tissue recombination and bFGF. 1995, Pubmed , Xenbase
Crossley, The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. 1995, Pubmed
Curran, Expression of activated MAP kinase in Xenopus laevis embryos: evaluating the roles of FGF and other signaling pathways in early induction and patterning. 2000, Pubmed , Xenbase
Dailey, Mechanisms underlying differential responses to FGF signaling. 2005, Pubmed
Danos, Role of notochord in specification of cardiac left-right orientation in zebrafish and Xenopus. 1996, Pubmed , Xenbase
Danos, Linkage of cardiac left-right asymmetry and dorsal-anterior development in Xenopus. 1995, Pubmed , Xenbase
Davidson, Exogenous FGF-4 can suppress anterior development in the mouse embryo during neurulation and early organogenesis. 2000, Pubmed
De Robertis, Dorsal-ventral patterning and neural induction in Xenopus embryos. 2004, Pubmed , Xenbase
De Robertis, Spemann's organizer and the self-regulation of embryonic fields. 2009, Pubmed , Xenbase
Delaune, Neural induction in Xenopus requires early FGF signalling in addition to BMP inhibition. 2005, Pubmed , Xenbase
Deng, Murine FGFR-1 is required for early postimplantation growth and axial organization. 1994, Pubmed , Xenbase
Dessimoz, FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo. 2006, Pubmed
Diez del Corral, Opposing FGF and retinoid pathways: a signalling switch that controls differentiation and patterning onset in the extending vertebrate body axis. 2004, Pubmed
Diez del Corral, Opposing FGF and retinoid pathways control ventral neural pattern, neuronal differentiation, and segmentation during body axis extension. 2003, Pubmed
Doniach, Basic FGF as an inducer of anteroposterior neural pattern. 1995, Pubmed
Draper, Zebrafish fgf24 functions with fgf8 to promote posterior mesodermal development. 2003, Pubmed
Dubrulle, fgf8 mRNA decay establishes a gradient that couples axial elongation to patterning in the vertebrate embryo. 2004, Pubmed
Durston, Retinoic acid causes an anteroposterior transformation in the developing central nervous system. 1989, Pubmed , Xenbase
Eivers, Integrating positional information at the level of Smad1/5/8. 2008, Pubmed , Xenbase
Essner, Conserved function for embryonic nodal cilia. 2002, Pubmed , Xenbase
Evans, Establishment in culture of pluripotential cells from mouse embryos. 1981, Pubmed
Feldman, Requirement of FGF-4 for postimplantation mouse development. 1995, Pubmed
Fischer, FGF8 acts as a right determinant during establishment of the left-right axis in the rabbit. 2002, Pubmed
Fisher, eFGF is required for activation of XmyoD expression in the myogenic cell lineage of Xenopus laevis. 2002, Pubmed , Xenbase
Fletcher, FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus. 2006, Pubmed , Xenbase
Fletcher, The role of FGF signaling in the establishment and maintenance of mesodermal gene expression in Xenopus. 2008, Pubmed , Xenbase
Fürthauer, A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula. 1997, Pubmed
Fürthauer, Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. 2004, Pubmed
Gisselbrecht, heartless encodes a fibroblast growth factor receptor (DFR1/DFGF-R2) involved in the directional migration of early mesodermal cells in the Drosophila embryo. 1996, Pubmed
Goldin, Paracrine action of FGF4 during periimplantation development maintains trophectoderm and primitive endoderm. 2003, Pubmed
Gospodarowicz, Mitogenic effect of fibroblast growth factor on early passage cultures of human and murine fibroblasts. 1975, Pubmed
Griffin, Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail. 1995, Pubmed
Gryzik, FGF8-like1 and FGF8-like2 encode putative ligands of the FGF receptor Htl and are required for mesoderm migration in the Drosophila gastrula. 2004, Pubmed
Hamada, Establishment of vertebrate left-right asymmetry. 2002, Pubmed
Hardcastle, FGF-8 stimulates neuronal differentiation through FGFR-4a and interferes with mesoderm induction in Xenopus embryos. 2000, Pubmed , Xenbase
Haremaki, Integration of multiple signal transducing pathways on Fgf response elements of the Xenopus caudal homologue Xcad3. 2003, Pubmed , Xenbase
Heisenberg, Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation. 2000, Pubmed
Holowacz, FGF is required for posterior neural patterning but not for neural induction. 1999, Pubmed , Xenbase
Hong, FGF-dependent left-right asymmetry patterning in zebrafish is mediated by Ier2 and Fibp1. 2009, Pubmed
Hongo, FGF signaling and the anterior neural induction in Xenopus. 1999, Pubmed , Xenbase
Houle, Retinoic acid regulation of Cdx1: an indirect mechanism for retinoids and vertebral specification. 2000, Pubmed , Xenbase
Houle, Retinoic acid regulates a subset of Cdx1 function in vivo. 2003, Pubmed
Hudson, Induction of anterior neural fates in the ascidian Ciona intestinalis. 2001, Pubmed
Ikeya, Wnt-3a is required for somite specification along the anteroposterior axis of the mouse embryo and for regulation of cdx-1 expression. 2001, Pubmed
Imai, Early embryonic expression of FGF4/6/9 gene and its role in the induction of mesenchyme and notochord in Ciona savignyi embryos. 2002, Pubmed
Inazawa, Basic fibroblast growth factor induction of neuronal ion channel expression in ascidian ectodermal blastomeres. 1998, Pubmed
Isaacs, FGF4 regulates blood and muscle specification in Xenopus laevis. 2007, Pubmed , Xenbase
Isaacs, eFGF regulates Xbra expression during Xenopus gastrulation. 1994, Pubmed , Xenbase
Isaacs, Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anteroposterior specification. 1992, Pubmed , Xenbase
Isaacs, Regulation of Hox gene expression and posterior development by the Xenopus caudal homologue Xcad3. 1998, Pubmed , Xenbase
Isaacs, eFGF is expressed in the dorsal midline of Xenopus laevis. 1995, Pubmed , Xenbase
Itoh, The Fgf families in humans, mice, and zebrafish: their evolutional processes and roles in development, metabolism, and disease. 2007, Pubmed
Itoh, Functional evolutionary history of the mouse Fgf gene family. 2008, Pubmed
Kadam, FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation. 2009, Pubmed
Keenan, FGF signal transduction and the regulation of Cdx gene expression. 2006, Pubmed , Xenbase
Kengaku, bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus. 1995, Pubmed , Xenbase
Kiecker, A morphogen gradient of Wnt/beta-catenin signalling regulates anteroposterior neural patterning in Xenopus. 2001, Pubmed , Xenbase
Kimelman, Mesoderm induction: from caps to chips. 2006, Pubmed , Xenbase
Kimelman, Synergistic induction of mesoderm by FGF and TGF-beta and the identification of an mRNA coding for FGF in the early Xenopus embryo. 1987, Pubmed , Xenbase
Kinoshita, PKC delta is essential for Dishevelled function in a noncanonical Wnt pathway that regulates Xenopus convergent extension movements. 2003, Pubmed , Xenbase
Klingseisen, Differential and overlapping functions of two closely related Drosophila FGF8-like growth factors in mesoderm development. 2009, Pubmed
Koshida, Inhibition of BMP activity by the FGF signal promotes posterior neural development in zebrafish. 2002, Pubmed , Xenbase
Krejci, Molecular pathology of the fibroblast growth factor family. 2009, Pubmed
Kroll, Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. 1996, Pubmed , Xenbase
Kudoh, Distinct roles for Fgf, Wnt and retinoic acid in posteriorizing the neural ectoderm. 2002, Pubmed
Kudoh, Combinatorial Fgf and Bmp signalling patterns the gastrula ectoderm into prospective neural and epidermal domains. 2004, Pubmed
Kumano, The nodal target gene Xmenf is a component of an FGF-independent pathway of ventral mesoderm induction in Xenopus. 2002, Pubmed , Xenbase
Kumano, Revisions to the Xenopus gastrula fate map: implications for mesoderm induction and patterning. 2002, Pubmed , Xenbase
Kumano, Boundaries and functional domains in the animal/vegetal axis of Xenopus gastrula mesoderm. 2001, Pubmed , Xenbase
Kumano, FGF signaling restricts the primary blood islands to ventral mesoderm. 2000, Pubmed , Xenbase
Kunath, FGF stimulation of the Erk1/2 signalling cascade triggers transition of pluripotent embryonic stem cells from self-renewal to lineage commitment. 2007, Pubmed
Kunath, Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. 2005, Pubmed
Lamb, Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. 1995, Pubmed , Xenbase
Lane, The origins of primitive blood in Xenopus: implications for axial patterning. 1999, Pubmed , Xenbase
Lane, Primitive and definitive blood share a common origin in Xenopus: a comparison of lineage techniques used to construct fate maps. 2002, Pubmed , Xenbase
Lanner, The role of FGF/Erk signaling in pluripotent cells. 2010, Pubmed
Launay, A truncated FGF receptor blocks neural induction by endogenous Xenopus inducers. 1996, Pubmed , Xenbase
Lea, Temporal and spatial expression of FGF ligands and receptors during Xenopus development. 2009, Pubmed , Xenbase
Leslie, PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration. 2007, Pubmed
Levine, Proposal of a model of mammalian neural induction. 2007, Pubmed
Li, Generation of rat and human induced pluripotent stem cells by combining genetic reprogramming and chemical inhibitors. 2009, Pubmed
Li, Germline competent embryonic stem cells derived from rat blastocysts. 2008, Pubmed
Lieschke, Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. 2002, Pubmed
Linker, Neural induction requires BMP inhibition only as a late step, and involves signals other than FGF and Wnt antagonists. 2004, Pubmed , Xenbase
Linker, Cell communication with the neural plate is required for induction of neural markers by BMP inhibition: evidence for homeogenetic induction and implications for Xenopus animal cap and chick explant assays. 2009, Pubmed , Xenbase
Little, Extracellular modulation of BMP activity in patterning the dorsoventral axis. 2006, Pubmed , Xenbase
Mariani, Genetic evidence that FGFs have an instructive role in limb proximal-distal patterning. 2008, Pubmed
Martin, Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. 1981, Pubmed
Mathis, FGF receptor signalling is required to maintain neural progenitors during Hensen's node progression. 2001, Pubmed
McGrew, Wnt and FGF pathways cooperatively pattern anteroposterior neural ectoderm in Xenopus. 1997, Pubmed , Xenbase
McGrew, Specification of the anteroposterior neural axis through synergistic interaction of the Wnt signaling cascade with noggin and follistatin. 1995, Pubmed , Xenbase
McIntosh, The pleiotropic effects of fibroblast growth factor receptors in mammalian development. 2000, Pubmed
Meyers, An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. 1998, Pubmed
Meyers, Differences in left-right axis pathways in mouse and chick: functions of FGF8 and SHH. 1999, Pubmed
Minina, Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation. 2002, Pubmed
Mohammadi, Structural basis for fibroblast growth factor receptor activation. 2005, Pubmed
Moreno, Regulation of segmental patterning by retinoic acid signaling during Xenopus somitogenesis. 2004, Pubmed , Xenbase
Neugebauer, FGF signalling during embryo development regulates cilia length in diverse epithelia. 2009, Pubmed , Xenbase
Nichols, Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo. 2009, Pubmed
Nichols, Validated germline-competent embryonic stem cell lines from nonobese diabetic mice. 2009, Pubmed
Niswander, FGF-4 and BMP-2 have opposite effects on limb growth. 1993, Pubmed
Northrop, Dorsal-ventral differences in Xcad-3 expression in response to FGF-mediated induction in Xenopus. 1994, Pubmed , Xenbase
Nutt, Xenopus Sprouty2 inhibits FGF-mediated gastrulation movements but does not affect mesoderm induction and patterning. 2001, Pubmed , Xenbase
Ohuchi, Involvement of androgen-induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. 1994, Pubmed
Olivera-Martinez, Wnt signals provide a timing mechanism for the FGF-retinoid differentiation switch during vertebrate body axis extension. 2007, Pubmed
Ornitz, FGFs, heparan sulfate and FGFRs: complex interactions essential for development. 2000, Pubmed
Ota, The roles of the FGF signal in zebrafish embryos analyzed using constitutive activation and dominant-negative suppression of different FGF receptors. 2009, Pubmed , Xenbase
Partanen, Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos. 1998, Pubmed
Pera, Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction. 2003, Pubmed , Xenbase
Pilon, Cdx4 is a direct target of the canonical Wnt pathway. 2006, Pubmed
Pownall, eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus. 1996, Pubmed , Xenbase
Rappolee, Expression and function of FGF-4 in peri-implantation development in mouse embryos. 1994, Pubmed
Reifers, Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis. 1998, Pubmed
Rentzsch, Fgf signaling induces posterior neuroectoderm independently of Bmp signaling inhibition. 2004, Pubmed
Ribes, Early mouse caudal development relies on crosstalk between retinoic acid, Shh and Fgf signalling pathways. 2009, Pubmed
Ribisi, Ras-mediated FGF signaling is required for the formation of posterior but not anterior neural tissue in Xenopus laevis. 2000, Pubmed , Xenbase
Rodríguez-Gallardo, Targeted over-expression of FGF in chick embryos induces formation of ectopic neural cells. 1997, Pubmed , Xenbase
Rossant, Stem cells and early lineage development. 2008, Pubmed
Röttinger, FGF signals guide migration of mesenchymal cells, control skeletal morphogenesis [corrected] and regulate gastrulation during sea urchin development. 2008, Pubmed
SAXEN, The two-gradient hypothesis in primary induction. The combined effect of two types of inductors mixed in different ratios. 1961, Pubmed
Sasai, Endoderm induction by the organizer-secreted factors chordin and noggin in Xenopus animal caps. 1996, Pubmed , Xenbase
Schier, Molecular genetics of axis formation in zebrafish. 2005, Pubmed
Schlessinger, Cell signaling by receptor tyrosine kinases. 2000, Pubmed
Shamim, Expression of Fgf4 during early development of the chick embryo. 1999, Pubmed
Sheng, Churchill, a zinc finger transcriptional activator, regulates the transition between gastrulation and neurulation. 2003, Pubmed , Xenbase
Shiotsugu, Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation. 2004, Pubmed , Xenbase
Silva, Capturing pluripotency. 2008, Pubmed
Sivak, FGF signal interpretation is directed by Sprouty and Spred proteins during mesoderm formation. 2005, Pubmed , Xenbase
Sive, Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis. 1990, Pubmed , Xenbase
Slack, Mesoderm induction in early Xenopus embryos by heparin-binding growth factors. , Pubmed , Xenbase
Stavridis, Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation. 2010, Pubmed
Stavridis, A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification. 2007, Pubmed
Stern, Neural induction: old problem, new findings, yet more questions. 2005, Pubmed , Xenbase
Storey, Early posterior neural tissue is induced by FGF in the chick embryo. 1998, Pubmed
Streit, Initiation of neural induction by FGF signalling before gastrulation. 2000, Pubmed
Sun, Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo. 1999, Pubmed
Tada, Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway. 2000, Pubmed , Xenbase
Takada, Wnt-3a regulates somite and tailbud formation in the mouse embryo. 1994, Pubmed
Tanaka, Promotion of trophoblast stem cell proliferation by FGF4. 1998, Pubmed
Tanaka, FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. 2005, Pubmed
Turner, Fibroblast growth factor signalling: from development to cancer. 2010, Pubmed
Walmsley, Fibroblast growth factor controls the timing of Scl, Lmo2, and Runx1 expression during embryonic blood development. 2008, Pubmed , Xenbase
Weaver, Move it or lose it: axis specification in Xenopus. 2004, Pubmed , Xenbase
Wells, Early mouse endoderm is patterned by soluble factors from adjacent germ layers. 2000, Pubmed
Wilkie, Bad bones, absent smell, selfish testes: the pleiotropic consequences of human FGF receptor mutations. 2005, Pubmed
Wills, BMP antagonists and FGF signaling contribute to different domains of the neural plate in Xenopus. 2010, Pubmed , Xenbase
Wilson, An early requirement for FGF signalling in the acquisition of neural cell fate in the chick embryo. 2000, Pubmed , Xenbase
Wilson, Stem cells, signals and vertebrate body axis extension. 2009, Pubmed
Xian, Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. 2005, Pubmed
Xu, Murine fibroblast growth factor receptor 1alpha isoforms mediate node regression and are essential for posterior mesoderm development. 1999, Pubmed
Xu, Opposite effects of FGF and BMP-4 on embryonic blood formation: roles of PV.1 and GATA-2. 1999, Pubmed , Xenbase
Yamaguchi, fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. 1994, Pubmed
Yamanaka, Cell and molecular regulation of the mouse blastocyst. 2006, Pubmed
Yamanaka, FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. 2010, Pubmed
Yamauchi, Fgf4 is required for left-right patterning of visceral organs in zebrafish. 2009, Pubmed
Yang, Cell movement patterns during gastrulation in the chick are controlled by positive and negative chemotaxis mediated by FGF4 and FGF8. 2002, Pubmed
Yasuo, FGF8/17/18 functions together with FGF9/16/20 during formation of the notochord in Ciona embryos. 2007, Pubmed
Ying, The ground state of embryonic stem cell self-renewal. 2008, Pubmed
Zhang, Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. 2006, Pubmed
Zhao, Effect of retinoic acid signaling on Wnt/beta-catenin and FGF signaling during body axis extension. 2009, Pubmed