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Plant Cell July 1, 2020; 32 (7): 2216-2236.
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STRESS INDUCED FACTOR 2 Regulates Arabidopsis Stomatal Immunity through Phosphorylation of the Anion Channel SLAC1.

Chan C , Panzeri D , Okuma E , Tõldsepp K , Wang YY , Louh GY , Chin TC , Yeh YH , Yeh HL , Yekondi S , Huang YH , Huang TY , Chiou TJ , Murata Y , Kollist H , Zimmerli L .

Upon recognition of microbes, pattern recognition receptors (PRRs) activate pattern-triggered immunity. FLAGELLIN SENSING2 (FLS2) and BRASSINOSTEROID INSENSITIVE1-ASSOCIATED KINASE1 (BAK1) form a typical PRR complex that senses bacteria. Here, we report that the kinase activity of the malectin-like receptor-like kinase STRESS INDUCED FACTOR 2 (SIF2) is critical for Arabidopsis (Arabidopsis thaliana) resistance to bacteria by regulating stomatal immunity. SIF2 physically associates with the FLS2-BAK1 PRR complex and interacts with and phosphorylates the guard cell SLOW ANION CHANNEL1 (SLAC1), which is necessary for abscisic acid (ABA)-mediated stomatal closure. SIF2 is also required for the activation of ABA-induced S-type anion currents in Arabidopsis protoplasts, and SIF2 is sufficient to activate SLAC1 anion channels in Xenopus oocytes. SIF2-mediated activation of SLAC1 depends on specific phosphorylation of Ser 65. This work reveals that SIF2 functions between the FLS2-BAK1 initial immunity receptor complex and the final actuator SLAC1 in stomatal immunity.

PubMed ID: 32327536
PMC ID: PMC7346559
Article link: Plant Cell

Species referenced: Xenopus
Genes referenced: mlec nectin1

References [+] :
Alonso, Genome-wide insertional mutagenesis of Arabidopsis thaliana. 2003, Pubmed