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Here we describe novel spherical structures that are induced by cold shock on the lampbrush chromosomes (LBCs) of Xenopus laevis oocytes. We call these structures cold bodies or C-bodies. C-bodies are distributed symmetrically on homologous LBCs, with a pattern similar to that of 5S rDNA. Neither active transcription nor translation is necessary for their formation. Similar protrusions occur on the edges of some nucleoli. Endogenous LBCs as well as those derived from injected sperm form C-bodies under cold shock conditions. The function of C-bodies is unknown.
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???displayArticle.pmcLink???PMC7771896 ???displayArticle.link???Exp Cell Res ???displayArticle.grants???[+]
Angelier,
Cold-induced changes in amphibian oocytes.
1989, Pubmed
Angelier,
Cold-induced changes in amphibian oocytes.
1989,
Pubmed
Bregman,
Transcription-dependent redistribution of the large subunit of RNA polymerase II to discrete nuclear domains.
1995,
Pubmed
Brown,
Specific gene amplification in oocytes. Oocyte nuclei contain extrachromosomal replicas of the genes for ribosomal RNA.
1968,
Pubmed
Callan,
Lampbrush chromosomes.
1986,
Pubmed
Gall,
Assembly of lampbrush chromosomes from sperm chromatin.
1998,
Pubmed
,
Xenbase
Gall,
Assembly of the nuclear transcription and processing machinery: Cajal bodies (coiled bodies) and transcriptosomes.
1999,
Pubmed
,
Xenbase
Gall,
Lampbrush chromosomes.
1991,
Pubmed
,
Xenbase
Gall,
The genes for ribosomal RNA during oögenesis.
1969,
Pubmed
Gall,
Examining the contents of isolated Xenopus germinal vesicles.
2010,
Pubmed
,
Xenbase
Gall,
Structure in the amphibian germinal vesicle.
2004,
Pubmed
,
Xenbase
Gall,
Differential synthesis of the genes for ribosomal RNA during amphibian oögenesis.
1968,
Pubmed
Handwerger,
Heat shock induces mini-Cajal bodies in the Xenopus germinal vesicle.
2002,
Pubmed
,
Xenbase
Hügle,
Ribocharin: a nuclear Mr 40,000 protein specific to precursor particles of the large ribosomal subunit.
1985,
Pubmed
,
Xenbase
Krainer,
Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs.
1988,
Pubmed
Liu,
Induction of human lampbrush chromosomes.
2012,
Pubmed
,
Xenbase
Murphy,
RNA polymerase III in Cajal bodies and lampbrush chromosomes of the Xenopus oocyte nucleus.
2002,
Pubmed
,
Xenbase
N'Da,
Effects of cold shock treatment on amphibian oocytes: alteration of heterogenous nuclear RNP morphology.
1990,
Pubmed
Schneider,
NIH Image to ImageJ: 25 years of image analysis.
2012,
Pubmed
Wallace,
Protein incorporation by isolated amphibian oocytes. 3. Optimum incubation conditions.
1973,
Pubmed
,
Xenbase
