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XB-ART-57896
Neuron 2021 Mar 03;1095:743-745. doi: 10.1016/j.neuron.2021.02.017.
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Xenopus models suggest convergence of gene signatures on neurogenesis in autism.

Brennand KJ , Talkowski ME .


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Willsey et al. dissect phenotypes associated with in vivo disruption of ten ASD-associated genes using a hypothesis-free, parallelized approach in Xenopus tropicalis. These studies continue to implicate cortical neurons in ASD pathogenesis and suggest a convergence on functions related to neurogenesis.

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