XB-ART-59316Development 2022 Sep 01;14917:. doi: 10.1242/dev.201215.
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The people behind the papers - Douglas Houston and Marko Horb.
Over the years, conflicting data have meant that the role of Wnt in symmetry breaking and axis formation was unclear. Now, a new paper published in Development finds that maternal Wnt11b is required for robust cortical rotation inXenopus laevis, which, in turn, is required for axis induction. To find out more about this story, we caught up with two of the authors, Douglas Houston, Professor at The University of Iowa, and Marko Horb, Director of the National Xenopus Resource at the Marine Biological Laboratory in Chicago.
PubMed ID: 36082762
Article link: Development
Species referenced: Xenopus laevis
Genes referenced: wnt11b