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XB-gRNA-23659187
| Genomic Target | tropicalis | laevis.L | laevis.S | ||||
| Identities | 19/20 | 19/20 | |||||
| genomic gRNA |
5' CCTCCTCTCCATCCTTTACT 3' ||||||||||||||||||| 3' GGAGGAGAGGTAGGAAATGG 5' | 5' CCTCCTCTCCATCCTTTACT 3' ||||||||||||||||||| 3' GGAGGAGAGGTAGGAAATGG 5' | |||||
Genomic Alignments  |
Position | Identity | Strand | Target | Genomic Target | ||
| laevis 10.1 | Chr7L:55387799..55387818 | 19/20 | Antisense | target | dlg5.L | ||
| Chr1S:116160103..116160122 | 16/20 | Antisense | off-target | kdm4c.S | |||
| Chr5L:112949167..112949186 | 16/20 | Antisense | off-target | meltf.L | |||
| Chr7S:40478763..40478782 | 18/20 | Sense | off-target | sh2d4b.S | |||
| Chr9_10L:42623778..42623797 | 17/20 | Sense | off-target | top1.1.L | |||
| Chr9_10S:99563153..99563172 | 18/20 | Antisense | off-target | ankfn1l.S | |||
| Chr3L:141931372..141931391 | 17/20 | Sense | off-target | camsap3.L | |||
| Chr3L:37822531..37822550 | 17/20 | Sense | off-target | adamts2.L | |||
| Chr7L:15905723..15905742 | 18/20 | Antisense | off-target | LOC108696109 | |||
| Chr8L:107154445..107154464 | 18/20 | Sense | off-target | LOC121397166 | |||
| Chr5S:6336287..6336306 | 18/20 | unknown | |||||
| Chr2S:15670531..15670550 | 17/20 | unknown | |||||
| Chr4S:101124920..101124939 | 17/20 | unknown | |||||
| Chr6L:15540032..15540051 | 16/20 | unknown | tropicalis 10.0 | Chr7:53774372..53774391 | 19/20 | 1 Antisense | target | dlg5 |
| Chr5:106093169..106093188 | 16/20 | 2 Antisense | off-target | meltf | |||
| Chr3:140807432..140807451 | 18/20 | 3 Antisense | off-target | cacna1a | |||
| Chr1:33039215..33039234 | 18/20 | 4 | unknown | ||||
| Chr5:352216..352235 | 17/20 | 5 | unknown | ||||
| Chr5:31921986..31922005 | 17/20 | 6 | unknown | ||||
| Chr6:33767327..33767346 | 16/20 | 7 | unknown | ||||
| Publications | |||||||
| First: |
DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes., J Med Genet 2021  |
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| Most recent: | |||||||
| View All Papers | |||||||
