Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Attributions Wiki
XB-GRNA-23659479
gRNA Name: vangl2 gRNA1
Synonyms: trop vangl2 T5, Xl.vangl2 (L+S)
Genomic Target: vangl2

PAM Sequence: TGG
Sequence: 5' TGCTGCTGCCCCAGATCCTATGG 3'



Genomic Target tropicalis laevis.L laevis.S
Identities 23/23 23/23 23/23
genome
gRNA
 
5' CCATAGGATCTGGGGCAGCAGCA 3'
   |||||||||||||||||||||||
3' GGTATCCTAGACCCCGTCGTCGT 5'
 
5' CCATAGGATCTGGGGCAGCAGCA 3'
   |||||||||||||||||||||||
3' GGTATCCTAGACCCCGTCGTCGT 5'
 
5' CCATAGGATCTGGGGCAGCAGCA 3'
   |||||||||||||||||||||||
3' GGTATCCTAGACCCCGTCGTCGT 5'
    
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr8S:99081795..99081817 23/23 Antisense target vangl2.S
Chr8L:127342346..127342368 23/23 Antisense target vangl2.L
Chr1S:142940101..142940123 19/23 Sense off-target ppil2.S
Chr2L:5151551..5151573 19/23 Sense off-target lsamp.L
Chr7L:137416665..137416687 19/23 Antisense off-target arhgef10l.L
Chr3S:58052686..58052708 19/23 Sense off-target LOC108712327
Chr1S:194282118..194282140 20/23 Antisense unknown
Chr3S:121917925..121917947 19/23 Antisense unknown
Chr9_10L:74351453..74351475 19/23 Sense unknown
tropicalis 10.0 Chr8:137134076..137134098 23/23 Antisense target vangl2
Chr5:152977871..152977893 19/23 Antisense off-target dnajc27
Chr8:146067692..146067714 19/23 Antisense unknown
Publications
???morpholino.displaySummary.papersFirst??? Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis., Dev Cell 2025     
???morpholino.displaySummary.papersRecent???
???morpholino.displaySummary.papersAll???