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XB-gRNA-25875083
gRNA Name:
lrp2 gRNA1
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' GCATAGGGAATGTGGTCCGG 3'
Synonyms:
Genomic Target: lrp2
PAM Sequence: GGG
Sequence: 5' GCATAGGGAATGTGGTCCGG 3'
| Genomic Target | tropicalis | laevis.L | laevis.S | ||||
| Identities | 20/20 | 20/20 | |||||
| genomic gRNA |
5' CCGGACCACATTCCCTATGC 3' |||||||||||||||||||| 3' GGCCTGGTGTAAGGGATACG 5' | 5' CCGGACCACATTCCCTATGC 3' |||||||||||||||||||| 3' GGCCTGGTGTAAGGGATACG 5' | |||||
Genomic Alignments  |
Position | Identity | Strand | Target | Genomic Target | ||
| laevis 10.1 | Chr9_10L:75069293..75069312 | 20/20 | Sense | target | lrp2.L | ||
| Chr9_10S:3575874..3575893 | 18/20 | Antisense | off-target | stk4.S | |||
| Chr9_10L:78547348..78547367 | 16/20 | Sense | off-target | hoxd10.L | |||
| Chr6S:26072561..26072580 | 18/20 | Antisense | off-target | ppp1r9a.S | |||
| Chr9_10L:129143452..129143471 | 16/20 | Sense | off-target | LOC121398222 | |||
| Chr9_10L:78547348..78547367 | 16/20 | Sense | off-target | LOC121397930 | |||
| Chr9_10L:128207878..128207897 | 17/20 | unknown | tropicalis 10.0 | Chr9:68763296..68763315 | 20/20 | 1 Sense | target | lrp2 |
| Chr3:91010310..91010329 | 18/20 | 2 Sense | off-target | acsbg1 | |||
| Chr9:64999703..64999722 | 16/20 | 3 Sense | off-target | LOC116406456 | |||
| Publications | |||||||
| First: |
Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds., Development 2021  |
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| Most recent: | |||||||
| View All Papers | |||||||
