cancer

Literature (140)

Literature for DOID 162: cancer

Xenbase Articles Publications associated with this Disease Ontology entry or its descendants

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The Wnt-dependent signaling pathways as target in oncology drug discovery., Janssens N,Janicot M,Perera T, Invest New Drugs. July 1, 2006; 24(4):0167-6997.
Fishing and frogging for anti-angiogenic drugs., De Smet F,Carmeliet P,Autiero M, Nat Chem Biol. May 1, 2006; 2(5):1552-4469.
Mechanism of proliferation arrest of embryonic cells of Xenopus by diterpene compounds., Okouchi T,Abe T,Araki S,Arai S,Iida T,Wang LY,Kitanaka S,Miyata S, Bioorg Med Chem. June 1, 2005; 13(11):1464-3391.
Kinetic properties of nuclear transport conferred by the retinoblastoma (Rb) NLS., Hu W,Kemp BE,Jans DA, J Cell Biochem. July 1, 2005; 95(4):0730-2312.
AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer., Zhang JS,Gong A,Cheville JC,Smith DI,Young CY, Genes Chromosomes Cancer. July 1, 2005; 43(3):1045-2257.
Induction of ectopic olfactory structures and bone morphogenetic protein inhibition by Rossy, a group XII secreted phospholipase A2., Muñoz-Sanjuán I,Brivanlou AH, Mol Cell Biol. May 1, 2005; 25(9):1098-5549.
ZW10 links mitotic checkpoint signaling to the structural kinetochore., Kops GJ,Kim Y,Weaver BA,Mao Y,McLeod I,Yates JR,Tagaya M,Cleveland DW, J Cell Biol. April 11, 2005; 169(1):1540-8140.
Analysis of missense variation in human BRCA1 in the context of interspecific sequence variation., Abkevich V,Zharkikh A,Deffenbaugh AM,Frank D,Chen Y,Chen Y,Shattuck D,Skolnick MH,Gutin A,Tavtigian SV, J Med Genet. July 1, 2004; 41(7):1468-6244.
Identification of a novel gene, FGFR1OP2, fused to FGFR1 in 8p11 myeloproliferative syndrome., Grand EK,Grand FH,Chase AJ,Ross FM,Corcoran MM,Oscier DG,Cross NC, Genes Chromosomes Cancer. May 1, 2004; 40(1):1045-2257.
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features., Roessler E,Du YZ,Mullor JL,Casas E,Allen WP,Gillessen-Kaesbach G,Roeder ER,Ming JE,Ruiz i Altaba A,Muenke M, Proc Natl Acad Sci U S A. November 11, 2003; 100(23):1091-6490.
Vertebrate hairy and Enhancer of split related proteins: transcriptional repressors regulating cellular differentiation and embryonic patterning., Davis RL,Turner DL, Oncogene. December 20, 2001; 20(58):0950-9232.
Expression cloning of Xenopus Os4, an evolutionarily conserved gene, which induces mesoderm and dorsal axis., Zohn IE,Brivanlou AH, Dev Biol. November 1, 2001; 239(1):1095-564X.
Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2)., Gao B,Sekido Y,Maximov A,Saad M,Forgacs E,Latif F,Wei MH,Lerman M,Lee JH,Lee JH,Perez-Reyes E,Bezprozvanny I,Minna JD, J Biol Chem. April 21, 2000; 275(16):1083-351X.
Mads and Smads in TGF beta signalling., Attisano L,Wrana JL, Curr Opin Cell Biol. April 1, 1998; 10(2):0955-0674.
p53 activity is essential for normal development in Xenopus., Wallingford JB,Seufert DW,Virta VC,Vize PD, Curr Biol. October 1, 1997; 7(10):0960-9822.
Notch in vertebrates., Robey E, Curr Opin Genet Dev. August 1, 1997; 7(4):0959-437X.
Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor., Tsutsumi M,Zhou W,Millar RP,Mellon PL,Roberts JL,Flanagan CA,Dong K,Gillo B,Sealfon SC, Mol Endocrinol. July 1, 1992; 6(7):1944-9917.
The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly., Joukov V,Groen AC,Prokhorova T,Gerson R,White E,Rodriguez A,Walter JC,Livingston DM, Cell. November 3, 2006; 127(3):1097-4172.
FoxM1: at the crossroads of ageing and cancer., Laoukili J,Stahl M,Medema RH, Biochim Biophys Acta. January 1, 2007; 1775(1):0006-3002.
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis., Kälin RE,Kretz MP,Meyer AM,Kispert A,Heppner FL,Brändli AW, Dev Biol. May 15, 2007; 305(2):1095-564X.
Molecular mechanisms of lymphatic vascular development., Mäkinen T,Norrmén C,Petrova TV, Cell Mol Life Sci. August 1, 2007; 64(15):1420-9071.
Dkk3 is required for TGF-beta signaling during Xenopus mesoderm induction., Pinho S,Niehrs C, Differentiation. December 1, 2007; 75(10):1432-0436.
Chimeric molecules to target proteins for ubiquitination and degradation., Sakamoto KM, Methods Enzymol. January 1, 2005; 399:1557-7988.
Non-transcriptional control of DNA replication by c-Myc., Dominguez-Sola D,Ying CY,Grandori C,Ruggiero L,Chen B,Li M,Galloway DA,Gu W,Gautier J,Dalla-Favera R, Nature. July 26, 2007; 448(7152):0143-5221.
WNTS and WNT receptors as therapeutic tools and targets in human disease processes., Chien AJ,Moon RT, Front Biosci. January 1, 2007; 12:1093-9946.
Twenty odd years of stretch-sensitive channels., Hamill OP, Pflugers Arch. December 1, 2006; 453(3):1432-2013.
Three matrix metalloproteinases are required in vivo for macrophage migration during embryonic development., Tomlinson ML,Garcia-Morales C,Abu-Elmagd M,Wheeler GN, Mech Dev. January 1, 2008; 125(11-12):1872-6356.
ING function in apoptosis in diverse model systems., Shah S,Smith H,Feng X,Rancourt DE,Riabowol K, Biochem Cell Biol. February 1, 2009; 87(1):1208-6002.
The colorectal cancer risk at 18q21 is caused by a novel variant altering SMAD7 expression., Pittman AM,Naranjo S,Webb E,Broderick P,Lips EH,van Wezel T,Morreau H,Sullivan K,Fielding S,Twiss P,Vijayakrishnan J,Casares F,Qureshi M,Gómez-Skarmeta JL,Houlston RS, Genome Res. June 1, 2009; 19(6):1549-5469.
Discovery and characterization of a small molecule inhibitor of the PDZ domain of dishevelled., Grandy D,Shan J,Zhang X,Rao S,Akunuru S,Li H,Zhang Y,Zhang Y,Alpatov I,Zhang XA,Lang RA,Shi DL,Zheng JJ, J Biol Chem. June 12, 2009; 284(24):1083-351X.
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis., Kälin RE,Bänziger-Tobler NE,Detmar M,Brändli AW, Blood. July 30, 2009; 114(5):1528-0020.
Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate., Li Y,Trojer P,Xu CF,Cheung P,Kuo A,Drury WJ,Qiao Q,Neubert TA,Xu RM,Gozani O,Reinberg D, J Biol Chem. December 4, 2009; 284(49):1083-351X.
Antitumor and anti-angiogenesis immunity induced by CR-SEREX-identified Xenopus RHAMM., Yang HS,Zhang DM,Deng HX,Peng F,Wei YQ, Cancer Sci. April 1, 2010; 101(4):1349-7006.
Aberrant activation of fatty acid synthesis suppresses primary cilium formation and distorts tissue development., Willemarck N,Rysman E,Brusselmans K,Van Imschoot G,Vanderhoydonc F,Moerloose K,Lerut E,Verhoeven G,van Roy F,Vleminckx K,Vleminckx K,Swinnen JV, Cancer Res. November 15, 2010; 70(22):1538-7445.
Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway., Blackiston D,Adams DS,Lemire JM,Lobikin M,Levin M, Dis Model Mech. January 1, 2011; 4(1):1754-8411.
Mitochondrial apoptosis-induced channel (MAC) function triggers a Bax/Bak-dependent bystander effect., Peixoto PM,Lue JK,Ryu SY,Wroble BN,Sible JC,Kinnally KW, Am J Pathol. January 1, 2011; 178(1):1525-2191.
Embryonic frog epidermis: a model for the study of cell-cell interactions in the development of mucociliary disease., Dubaissi E,Papalopulu N, Dis Model Mech. March 1, 2011; 4(2):1754-8411.
Epigenetic reprogramming of breast cancer cells with oocyte extracts., Allegrucci C,Rushton MD,Dixon JE,Sottile V,Shah M,Kumari R,Watson S,Alberio R,Johnson AD, Mol Cancer. January 13, 2011; 10(1):1476-4598.
FAK and WNT signaling: the meeting of two pathways in cancer and development., Fonar Y,Frank D, Anticancer Agents Med Chem. September 1, 2011; 11(7):1875-5992.
SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton., Langdon Y,Tandon P,Paden E,Duddy J,Taylor JM,Conlon FL, Development. March 1, 2012; 139(5):1477-9129.
Targeted inactivation of Snail family EMT regulatory factors by a Co(III)-Ebox conjugate., Harney AS,Meade TJ,LaBonne C, PLoS One. January 1, 2012; 7(2):1932-6203.
The Xenopus oocyte: a model for studying the metabolic regulation of cancer cell death., Nutt LK, Semin Cell Dev Biol. June 1, 2012; 23(4):1096-3634.
Ca2+-activated Cl- channels at a glance., Berg J,Yang H,Jan LY, J Cell Sci. March 15, 2012; 125(Pt 6):1477-9137.
Xenopus as a model system for the study of GOLPH2/GP73 function: Xenopus GOLPH2 is required for pronephros development., Li L,Wen L,Gong Y,Mei G,Liu J,Chen Y,Chen Y,Peng T, PLoS One. January 1, 2012; 7(6):1932-6203.
Isthmin inhibits glioma growth through antiangiogenesis in vivo., Yuan B,Xian R,Ma J,Chen Y,Chen Y,Lin C,Song Y, J Neurooncol. September 1, 2012; 109(2):1573-7373.
Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo., Lobikin M,Chernet B,Lobo D,Levin M, Phys Biol. December 1, 2012; 9(6):1478-3975.
Withaferin A induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance., Khan S,Rammeloo AW,Heikkila JJ, PLoS One. January 1, 2012; 7(11):1932-6203.
Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT,Levin M, Dis Model Mech. May 1, 2013; 6(3):1754-8411.
Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.
ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.
A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model., Haynes-Gilmore N,Banach M,Edholm ES,Lord E,Robert J, Carcinogenesis. August 1, 2014; 35(8):1460-2180.
Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.
Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT,Fields C,Levin M, Front Physiol. January 19, 2015; 5:1664-042X.
Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration., Haynes-Gimore N,Banach M,Brown E,Dawes R,Edholm ES,Kim M,Robert J, Dev Biol. December 15, 2015; 408(2):1095-564X.
Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.
Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.
An oncologist׳s friend: How Xenopus contributes to cancer research., Hardwick LJ,Philpott A, Dev Biol. December 15, 2015; 408(2):1095-564X.
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.
TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.
9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.
Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation., Lobikin M,Lobo D,Blackiston DJ,Martyniuk CJ,Tkachenko E,Levin M, Sci Signal. October 6, 2015; 8(397):1937-9145.
CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus., Bhattacharya D,Marfo CA,Li D,Lane M,Khokha MK, Dev Biol. December 15, 2015; 408(2):1095-564X.
Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging., Wei L,Tominaga H,Ohgaki R,Wiriyasermkul P,Hagiwara K,Okuda S,Kaira K,Oriuchi N,Nagamori S,Kanai Y, Cancer Sci. March 1, 2016; 107(3):1349-7006.
Identification of anti-cancer chemical compounds using Xenopus embryos., Tanaka M,Kuriyama S,Itoh G,Kohyama A,Iwabuchi Y,Shibata H,Yashiro M,Aiba N, Cancer Sci. June 1, 2016; 107(6):1349-7006.
Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N,Maccarana M,Strate I,von Stedingk K,Malmström A,Pera EM, Dis Model Mech. June 1, 2016; 9(6):1754-8411.
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.
CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.
TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.
Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.
Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ,Xie SX,Chen YT,Chen YT,Xue JL,Zhang CJ,Zhu F, World J Gastroenterol. September 7, 2016; 22(33):2219-2840.
Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z,Zhang Z,Zhang Z,Lei A,Xu L,Chen L,Chen Y,Chen Y,Zhang X,Gao Y,Yang X,Zhang M,Cao Y,Cao Y, J Biol Chem. August 4, 2017; 292(31):1083-351X.
TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L,Li Q,Yang J,Qiao B, J Cell Biochem. February 1, 2018; 119(2):0730-2312.
Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy., Kucinska M,Murias M,Nowak-Sliwinska P, Mutat Res Rev Mutat Res. July 1, 2017; 773:1388-2139.
The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines., Gardner NJ,Gillespie PJ,Carrington JT,Shanks EJ,McElroy SP,Haagensen EJ,Frearson JA,Woodland A,Blow JJ, Cell Chem Biol. August 17, 2017; 24(8):2451-9456.
A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., Plouhinec JL,Medina-Ruiz S,Borday C,Bernard E,Vert JP,Eisen MB,Harland RM,Monsoro-Burq AH, PLoS Biol. October 19, 2017; 15(10):1545-7885.
RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6., Szenker-Ravi E,Altunoglu U,Leushacke M,Bosso-Lefèvre C,Khatoo M,Thi Tran H,Naert T,Noelanders R,Hajamohideen A,Beneteau C,de Sousa SB,Karaman B,Latypova X,Başaran S,Yücel EB,Tan TT,Vlaminck L,Nayak SS,Shukla A,Girisha KM,Le Caignec C,Soshnikova N,Uyguner ZO,Vleminckx K,Vleminckx K,Barker N,Kayserili H,Reversade B, Nature. May 1, 2018; 557(7706):0143-5221.
Overexpression of TPX2 is associated with progression and prognosis of prostate cancer., Zou J,Huang RY,Jiang FN,Chen DX,Wang C,Wang C,Wang C,Han ZD,Liang YX,Zhong WD, Oncol Lett. September 1, 2018; 16(3):1792-1074.
Cancer Models in Xenopus tropicalis by CRISPR/Cas9 Mediated Knockout of Tumor Suppressors., Naert T,Vleminckx K,Vleminckx K, Methods Mol Biol. January 1, 2018; 1865:1940-6029.
CRISPR/Cas9 disease models in zebrafish and Xenopus: The genetic renaissance of fish and frogs., Naert T,Vleminckx K,Vleminckx K, Drug Discov Today Technol. August 1, 2018; 28:1740-6749.
TPX2 level correlates with cholangiocarcinoma cell proliferation, apoptosis, and EMT., Zou Z,Zheng B,Li J,Lv X,Zhang H,Yu F,Kong L,Li Y,Yu M,Fang L,Liang B, Biomed Pharmacother. November 1, 2018; 107:0753-3322.
DNp73-induced degradation of tyrosinase links depigmentation with EMT-driven melanoma progression., Fürst K,Steder M,Logotheti S,Angerilli A,Spitschak A,Marquardt S,Schumacher T,Engelmann D,Herchenröder O,Rupp RAW,Pützer BM, Cancer Lett. February 1, 2019; 442:0304-3835.
Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.
Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor., Jalvy S,Veschambre P,Fédou S,Rezvani HR,Thézé N,Thiébaud P, Dev Biol. March 15, 2019; 447(2):1095-564X.
Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network., Arnold TR,Shawky JH,Stephenson RE,Dinshaw KM,Higashi T,Huq F,Davidson LA,Davidson LA,Miller AL,Miller AL, Elife. January 31, 2019; 8:2050-084X.
The clinical significance and prognostic value of Xenopus kinesin-like protein 2 expressions in human tumors: A systematic review and meta-analysis., Yang W,Wan H,Shan R,Wen W,Li J,Luo D,Wan RH, J Cell Physiol. September 1, 2019; 234(9):1097-4652.
Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.
ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer., Daulat AM,Finetti P,Revinski D,Silveira Wagner M,Camoin L,Audebert S,Birnbaum D,Kodjabachian L,Borg JP,Bertucci F, Br J Cancer. April 1, 2019; 120(9):0007-0920.
Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.
Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN,Aguero TH,Owens DA,Kurtenbach S,Field MG,Durante MA,Rodriguez DA,King ML,Harbour JW, Sci Adv. September 18, 2019; 5(9):2375-2548.
Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Heintzman DR,Campos LV,Byl JAW,Osheroff N,Dewar JM, Cell Rep. October 8, 2019; 29(2):2211-1247.
Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K,Pipka JL,Chiang C,Liu Y,Clark RA,Keller R,Skoglund P,Guertin MJ,Hall IM,Stukenberg PT, Cell Rep. May 29, 2018; 23(9):2211-1247.
Subcellular Localization of the TFF Peptides xP1 and xP4 in the Xenopus laevis Gastric/Esophageal Mucosa: Different Secretion Modes Reflecting Diverse Protective Functions., Schwarz H,Hoffmann W, Int J Mol Sci. January 23, 2020; 21(3):1422-0067.
RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T,Dimitrakopoulou D,Tulkens D,Demuynck S,Carron M,Noelanders R,Eeckhout L,Van Isterdael G,Deforce D,Vanhove C,Van Dorpe J,Creytens D,Vleminckx K,Vleminckx K, Oncogene. March 1, 2020; 39(13):0950-9232.
Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation., Segovia M,Russo S,Jeldres M,Mahmoud YD,Perez V,Duhalde M,Charnet P,Rousset M,Victoria S,Veigas F,Louvet C,Vanhove B,Floto RA,Anegon I,Cuturi MC,Girotti MR,Rabinovich GA,Hill M, Cancer Cell. May 13, 2019; 35(5):1535-6108.
RINGO/Speedy proteins, a family of non-canonical activators of CDK1 and CDK2., Gonzalez L,Nebreda AR, Semin Cell Dev Biol. November 1, 2020; 107:1096-3634.
Rspo2 antagonizes FGF signaling during vertebrate mesoderm formation and patterning., Reis AH,Sokol SY, Development. May 27, 2020; 147(10):1477-9129.
Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Prevost MS,Bouchenaki H,Barilone N,Gielen M,Corringer PJ, Cell Mol Life Sci. February 1, 2021; 78(3):1420-9071.
Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.
Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.
Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.
Experimental Approaches to Identify Selective Picomolar Inhibitors for Carbonic Anhydrase IX., Kazokaitė-Adomaitienė J,Becker HM,Smirnovienė J,Dubois LJ,Matulis D, Curr Med Chem. January 1, 2021; 28(17):1875-533X.
R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H,Lee H,Seidl C,Sun R,Glinka A,Niehrs C, Nat Commun. November 4, 2020; 11(1):2041-1723.
Overexpression of TPX2 predicts poor clinical outcome and is associated with immune infiltration in hepatic cell cancer., Zhu H,Liu J,Feng J,Zhang Q,Bian T,Li X,Sun H,Zhang J,Liu Y, Medicine (Baltimore). December 4, 2020; 99(49):1536-5964.
Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.
Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.
Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.
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Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.
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Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.
Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N,De Robertis EM, Proc Natl Acad Sci U S A. April 26, 2022; 119(17):1091-6490.
Ventx Family and Its Functional Similarities with Nanog: Involvement in Embryonic Development and Cancer Progression., Kumar S,Kumar S,Kumar S,Kumar V,Li W,Kim J, Int J Mol Sci. March 1, 2022; 23(5):1422-0067.
Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.
Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.
Characteristic tetraspanin expression patterns mark various tissues during early Xenopus development., Kuriyama S,Tanaka M, Dev Growth Differ. February 1, 2023; 65(2):1440-169X.
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.
The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.
Exploring the Structural and Functional Diversity among FGF Signals: A Comparative Study of Human, Mouse, and Xenopus FGF Ligands in Embryonic Development and Cancer Pathogenesis., Goutam RS,Kumar V,Lee U,Kim J, Int J Mol Sci. April 20, 2023; 24(8):1422-0067.
TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.
ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.
Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.
The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.
Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.

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Learning about cancer from frogs: analysis of mitotic spindles in Xenopus egg extracts., Cross MK,Powers MA, Dis Model Mech. January 1, 2009; 2(11-12):1754-8411.

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Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model., Chernet BT,Levin M, Dis Model Mech. May 1, 2013; 6(3):1754-8411.

Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells., De Robertis A,Valensin S,Rossi M,Tunici P,Verani M,De Rosa A,Giordano C,Varrone M,Nencini A,Pratelli C,Benicchi T,Bakker A,Hill J,Sangthongpitag K,Pendharkar V,Liu B,Ng FM,Then SW,Jing Tai S,Cheong SM,He X,Caricasole A,Salerno M, Mol Cancer Ther. July 1, 2013; 12(7):1538-8514.

ZC88, a novel 4-amino piperidine analog, inhibits the growth of neuroblastoma cells through blocking hERG potassium channel., Wei X,Sun H,Yan H,Zhang C,Zhang S,Liu X,Hua N,Ma X,Zheng J, Cancer Biol Ther. May 1, 2013; 14(5):1555-8576.

A critical role of non-classical MHC in tumor immune evasion in the amphibian Xenopus model., Haynes-Gilmore N,Banach M,Edholm ES,Lord E,Robert J, Carcinogenesis. August 1, 2014; 35(8):1460-2180.

Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway., Amado NG,Predes D,Fonseca BF,Cerqueira DM,Reis AH,Dudenhoeffer AC,Borges HL,Mendes FA,Abreu JG, J Biol Chem. December 19, 2014; 289(51):1083-351X.

Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos., Chernet BT,Fields C,Levin M, Front Physiol. January 19, 2015; 5:1664-042X.

Semi-solid tumor model in Xenopus laevis/gilli cloned tadpoles for intravital study of neovascularization, immune cells and melanophore infiltration., Haynes-Gimore N,Banach M,Brown E,Dawes R,Edholm ES,Kim M,Robert J, Dev Biol. December 15, 2015; 408(2):1095-564X.

Derricin and derricidin inhibit Wnt/β-catenin signaling and suppress colon cancer cell growth in vitro., Fonseca BF,Predes D,Cerqueira DM,Reis AH,Amado NG,Cayres MC,Kuster RM,Oliveira FL,Mendes FA,Abreu JG, PLoS One. March 16, 2015; 10(3):1932-6203.

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma., Wylie LA,Hardwick LJ,Papkovskaia TD,Thiele CJ,Philpott A, Dis Model Mech. May 1, 2015; 8(5):1754-8411.

An oncologist׳s friend: How Xenopus contributes to cancer research., Hardwick LJ,Philpott A, Dev Biol. December 15, 2015; 408(2):1095-564X.

A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy., Raymond A,Liu B,Liang H,Wei C,Guindani M,Lu Y,Liang S,St John LS,Molldrem J,Nagarajan L, Oncotarget. December 30, 2014; 5(24):1949-2553.

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis., Van Nieuwenhuysen T,Naert T,Tran HT,Van Imschoot G,Geurs S,Sanders E,Creytens D,Van Roy F,Vleminckx K,Vleminckx K, Oncoscience. May 19, 2015; 2(5):2331-4737.

9B.03: A NOVEL INSERTIONAL SOMATIC KCNJ5 MUTATION IN AN AUSTRALIAN PATIENT WITH AN ALDOSTERONE PRODUCING ADENOMA., Xu S,Hardege I,Murthy M,Gordon R,Stowasser M,OʼShaughnessy K, J Hypertens. June 1, 2015; 33 Suppl 1:1473-5598.

Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation., Lobikin M,Lobo D,Blackiston DJ,Martyniuk CJ,Tkachenko E,Levin M, Sci Signal. October 6, 2015; 8(397):1937-9145.

CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus., Bhattacharya D,Marfo CA,Li D,Lane M,Khokha MK, Dev Biol. December 15, 2015; 408(2):1095-564X.

Specific transport of 3-fluoro-l-α-methyl-tyrosine by LAT1 explains its specificity to malignant tumors in imaging., Wei L,Tominaga H,Ohgaki R,Wiriyasermkul P,Hagiwara K,Okuda S,Kaira K,Oriuchi N,Nagamori S,Kanai Y, Cancer Sci. March 1, 2016; 107(3):1349-7006.

Identification of anti-cancer chemical compounds using Xenopus embryos., Tanaka M,Kuriyama S,Itoh G,Kohyama A,Iwabuchi Y,Shibata H,Yashiro M,Aiba N, Cancer Sci. June 1, 2016; 107(6):1349-7006.

Musculocontractural Ehlers-Danlos syndrome and neurocristopathies: dermatan sulfate is required for Xenopus neural crest cells to migrate and adhere to fibronectin., Gouignard N,Maccarana M,Strate I,von Stedingk K,Malmström A,Pera EM, Dis Model Mech. June 1, 2016; 9(6):1754-8411.

Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer., Puvirajesinghe TM,Bertucci F,Jain A,Scerbo P,Belotti E,Audebert S,Sebbagh M,Lopez M,Brech A,Finetti P,Charafe-Jauffret E,Chaffanet M,Castellano R,Restouin A,Marchetto S,Collette Y,Gonçalvès A,Macara I,Birnbaum D,Kodjabachian L,Johansen T,Borg JP, Nat Commun. January 12, 2016; 7:2041-1723.

CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis., Naert T,Colpaert R,Van Nieuwenhuysen T,Dimitrakopoulou D,Leoen J,Haustraete J,Boel A,Steyaert W,Lepez T,Deforce D,Willaert A,Creytens D,Vleminckx K,Vleminckx K, Sci Rep. October 14, 2016; 6:2045-2322.

TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models., Naert T,Van Nieuwenhuysen T,Vleminckx K,Vleminckx K, Genesis. January 1, 2017; 55(1-2):1526-968X.

Using Xenopus to understand human disease and developmental disorders., Sater AK,Moody SA, Genesis. January 1, 2017; 55(1-2):1526-968X.

Aberrant regulation of Wnt signaling in hepatocellular carcinoma., Liu LJ,Xie SX,Chen YT,Chen YT,Xue JL,Zhang CJ,Zhu F, World J Gastroenterol. September 7, 2016; 22(33):2219-2840.

Similarity in gene-regulatory networks suggests that cancer cells share characteristics of embryonic neural cells., Zhang Z,Zhang Z,Zhang Z,Lei A,Xu L,Chen L,Chen Y,Chen Y,Zhang X,Gao Y,Yang X,Zhang M,Cao Y,Cao Y, J Biol Chem. August 4, 2017; 292(31):1083-351X.

TPX2-p53-GLIPR1 regulatory circuitry in cell proliferation, invasion, and tumor growth of bladder cancer., Yan L,Li Q,Yang J,Qiao B, J Cell Biochem. February 1, 2018; 119(2):0730-2312.

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Targeting TPX2 suppresses proliferation and promotes apoptosis via repression of the PI3k/AKT/P21 signaling pathway and activation of p53 pathway in breast cancer., Chen M,Zhang H,Zhang G,Zhong A,Ma Q,Kai J,Tong Y,Xie S,Wang Y,Zheng H,Guo L,Lu R, Biochem Biophys Res Commun. December 9, 2018; 507(1-4):1090-2104.

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Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Dimitrakopoulou D,Tulkens D,Van Vlierberghe P,Vleminckx K,Vleminckx K, Front Physiol. January 1, 2019; 10:1664-042X.

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Sorafenib Activity and Disposition in Liver Cancer Does Not Depend on Organic Cation Transporter 1., Chen M,Neul C,Schaeffeler E,Frisch F,Winter S,Schwab M,Koepsell H,Hu S,Laufer S,Baker SD,Sparreboom A,Nies AT, Clin Pharmacol Ther. January 1, 2020; 107(1):1532-6535.

Characteristics of in Vivo Model Systems for Ovarian Cancer Studies., Tudrej P,Kujawa KA,Cortez AJ,Lisowska KM, Diagnostics (Basel). September 14, 2019; 9(3):2075-4418.

BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Kuznetsov JN,Aguero TH,Owens DA,Kurtenbach S,Field MG,Durante MA,Rodriguez DA,King ML,Harbour JW, Sci Adv. September 18, 2019; 5(9):2375-2548.

Topoisomerase II Is Crucial for Fork Convergence during Vertebrate Replication Termination., Heintzman DR,Campos LV,Byl JAW,Osheroff N,Dewar JM, Cell Rep. October 8, 2019; 29(2):2211-1247.

Identification of Drivers of Aneuploidy in Breast Tumors., Pfister K,Pipka JL,Chiang C,Liu Y,Clark RA,Keller R,Skoglund P,Guertin MJ,Hall IM,Stukenberg PT, Cell Rep. May 29, 2018; 23(9):2211-1247.

Subcellular Localization of the TFF Peptides xP1 and xP4 in the Xenopus laevis Gastric/Esophageal Mucosa: Different Secretion Modes Reflecting Diverse Protective Functions., Schwarz H,Hoffmann W, Int J Mol Sci. January 23, 2020; 21(3):1422-0067.

RBL1 (p107) functions as tumor suppressor in glioblastoma and small-cell pancreatic neuroendocrine carcinoma in Xenopus tropicalis., Naert T,Dimitrakopoulou D,Tulkens D,Demuynck S,Carron M,Noelanders R,Eeckhout L,Van Isterdael G,Deforce D,Vanhove C,Van Dorpe J,Creytens D,Vleminckx K,Vleminckx K, Oncogene. March 1, 2020; 39(13):0950-9232.

Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation., Segovia M,Russo S,Jeldres M,Mahmoud YD,Perez V,Duhalde M,Charnet P,Rousset M,Victoria S,Veigas F,Louvet C,Vanhove B,Floto RA,Anegon I,Cuturi MC,Girotti MR,Rabinovich GA,Hill M, Cancer Cell. May 13, 2019; 35(5):1535-6108.

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Concatemers to re-investigate the role of α5 in α4β2 nicotinic receptors., Prevost MS,Bouchenaki H,Barilone N,Gielen M,Corringer PJ, Cell Mol Life Sci. February 1, 2021; 78(3):1420-9071.

Mambalgin-2 Induces Cell Cycle Arrest and Apoptosis in Glioma Cells via Interaction with ASIC1a., Bychkov M,Shulepko M,Osmakov D,Andreev Y,Sudarikova A,Vasileva V,Pavlyukov MS,Latyshev YA,Potapov AA,Kirpichnikov M,Shenkarev ZO,Lyukmanova E, Cancers (Basel). July 8, 2020; 12(7):2072-6694.

Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma., Kuznetsoff JN,Owens DA,Lopez A,Rodriguez DA,Chee NT,Kurtenbach S,Bilbao D,Roberts ER,Volmar CH,Wahlestedt C,Brothers SP,Harbour JW, Mol Cancer Res. February 1, 2021; 19(2):1557-3125.

Allosteric regulation of mammalian Na+/I- symporter activity by perchlorate., Llorente-Esteban A,Manville RW,Reyna-Neyra A,Abbott GW,Amzel LM,Carrasco N, Nat Struct Mol Biol. June 1, 2020; 27(6):1545-9985.

Experimental Approaches to Identify Selective Picomolar Inhibitors for Carbonic Anhydrase IX., Kazokaitė-Adomaitienė J,Becker HM,Smirnovienė J,Dubois LJ,Matulis D, Curr Med Chem. January 1, 2021; 28(17):1875-533X.

R-spondins are BMP receptor antagonists in Xenopus early embryonic development., Lee H,Lee H,Seidl C,Sun R,Glinka A,Niehrs C, Nat Commun. November 4, 2020; 11(1):2041-1723.

Overexpression of TPX2 predicts poor clinical outcome and is associated with immune infiltration in hepatic cell cancer., Zhu H,Liu J,Feng J,Zhang Q,Bian T,Li X,Sun H,Zhang J,Liu Y, Medicine (Baltimore). December 4, 2020; 99(49):1536-5964.

Xenopus leads the way: Frogs as a pioneering model to understand the human brain., Exner CRT,Willsey HR, Genesis. February 1, 2021; 59(1-2):1526-968X.

Xenopus epidermal and endodermal epithelia as models for mucociliary epithelial evolution, disease, and metaplasia., Walentek P, Genesis. February 1, 2021; 59(1-2):1526-968X.

Use of Xenopus laevis cell-free extracts to study BRCA2 role in chromosome alignment., El Dika M, DNA Repair (Amst). April 1, 2021; 100:1568-7856.

Geoffroea decorticans fruit extracts inhibit the wnt/β-catenin pathway, a therapeutic target in cancer., Somaini GC,Aybar MJ,Aybar MJ,Vera NR,Tríbulo C, Biochem Biophys Res Commun. March 26, 2021; 546:1090-2104.

BRCA1-BARD1 regulates transcription through BRD4 in Xenopus nucleoplasmic extract., Barrows JK,Fullbright G,Long DT, Nucleic Acids Res. April 6, 2021; 49(6):1362-4962.

High nuclear TPX2 expression correlates with TP53 mutation and poor clinical behavior in a large breast cancer cohort, but is not an independent predictor of chromosomal instability., Matson DR,Denu RA,Zasadil LM,Burkard ME,Weaver BA,Flynn C,Stukenberg PT, BMC Cancer. February 23, 2021; 21(1):1471-2407.

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer., Levin M, Cell. April 15, 2021; :1097-4172.

HPF1-dependent PARP activation promotes LIG3-XRCC1-mediated backup pathway of Okazaki fragment ligation., Kumamoto S,Nishiyama A,Chiba Y,Miyashita R,Konishi C,Azuma Y,Nakanishi M, Nucleic Acids Res. May 21, 2021; 49(9):1362-4962.

High-resolution structures of multiple 5-HT3AR-setron complexes reveal a novel mechanism of competitive inhibition., Basak S,Kumar A,Ramsey S,Gibbs E,Kapoor A,Filizola M,Chakrapani S, Elife. October 16, 2020; 9:2050-084X.

Anaplastic lymphoma kinase (alk), a neuroblastoma associated gene, is expressed in neural crest domains during embryonic development of Xenopus., Moreno MM,Barrell WB,Godwin A,Guille M,Liu KJ,Liu KJ, Gene Expr Patterns. June 1, 2021; 40:1567-133X.

LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components., Fan Y,Köberlin MS,Ratnayeke N,Liu C,Deshpande M,Gerhardt J,Meyer T, J Cell Biol. August 2, 2021; 220(8):1540-8140.

Modeling endoderm development and disease in Xenopus., Edwards NA,Zorn AM, Curr Top Dev Biol. January 1, 2021; 145:1557-8933.

Generation of anisotropic strain dysregulates wild-type cell division at the interface between host and oncogenic tissue., Moruzzi M,Nestor-Bergmann A,Goddard GK,Tarannum N,Brennan K,Woolner S, Curr Biol. August 9, 2021; 31(15):0960-9822.

Neonatal NaV 1.5 channels: pharmacological distinctiveness of a cancer-related voltage-gated sodium channel splice variant., Fraser SP,Onkal R,Theys M,Bosmans F,Djamgoz MBA, Br J Pharmacol. February 1, 2022; 179(3):1476-5381.

Crosstalk between repair pathways elicits double-strand breaks in alkylated DNA and implications for the action of temozolomide., Fuchs RP,Isogawa A,Paulo JA,Onizuka K,Takahashi T,Amunugama R,Duxin JP,Fujii S, Elife. July 8, 2021; 10:2050-084X.

Weight of Evidence and Human Relevance Evaluation of the Benfluralin Mode of Action in Rats (Part II): Thyroid carcinogenesis., Strupp C,Quesnot N,Weber-Parmentier C,Richert L,Bomann WH,Singh P, Regul Toxicol Pharmacol. November 1, 2020; 117:1096-0295.

Modeling human congenital disorders with neural crest developmental defects using patient-derived induced pluripotent stem cells., Okuno H,Okano H, Regen Ther. August 24, 2021; 18:2352-3204.

CRISPR-SID: Identifying EZH2 as a druggable target for desmoid tumors via in vivo dependency mapping., Naert T,Tulkens D,Van Nieuwenhuysen T,Przybyl J,Demuynck S,van de Rijn M,Al-Jazrawe M,Alman BA,Coucke PJ,De Leeneer K,Vanhove C,Savvides SN,Creytens D,Vleminckx K,Vleminckx K, Proc Natl Acad Sci U S A. November 23, 2021; 118(47):1091-6490.

Structure-based screening combined with computational and biochemical analyses identified the inhibitor targeting the binding of DNA Ligase 1 to UHRF1., Kori S,Shibahashi Y,Ekimoto T,Nishiyama A,Yoshimi S,Yamaguchi K,Nagatoishi S,Ohta M,Tsumoto K,Nakanishi M,Defossez PA,Ikeguchi M,Arita K, Bioorg Med Chem. December 15, 2021; 52:1464-3391.

The Ubiquitin Ligase TRAIP: Double-Edged Sword at the Replisome., Wu RA,Pellman DS,Walter JC, Trends Cell Biol. February 1, 2021; 31(2):1879-3088.

Uncoupling the BMP receptor antagonist function from the WNT agonist function of R-spondin 2 using the inhibitory peptide dendrimer RWd., Lee H,Lee H,Sun R,Niehrs C, J Biol Chem. February 1, 2022; 298(2):1083-351X.

Engineered Wnt ligands enable blood-brain barrier repair in neurological disorders., Martin M,Vermeiren S,Bostaille N,Eubelen M,Spitzer D,Vermeersch M,Profaci CP,Pozuelo E,Toussay X,Raman-Nair J,Tebabi P,America M,De Groote A,Sanderson LE,Cabochette P,Germano RFV,Torres D,Boutry S,de Kerchove d'Exaerde A,Bellefroid EJ,Phoenix TN,Devraj K,Lacoste B,Daneman R,Liebner S,Vanhollebeke B, Science. February 18, 2022; 375(6582):1095-9203.

Lysosomes are required for early dorsal signaling in the Xenopus embryo., Tejeda-Muñoz N,De Robertis EM, Proc Natl Acad Sci U S A. April 26, 2022; 119(17):1091-6490.

Ventx Family and Its Functional Similarities with Nanog: Involvement in Embryonic Development and Cancer Progression., Kumar S,Kumar S,Kumar S,Kumar V,Li W,Kim J, Int J Mol Sci. March 1, 2022; 23(5):1422-0067.

Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells., Chandrasekera P,Perfetto M,Lu C,Zhuo M,Bahudhanapati H,Li J,Chen WC,Kulkarni P,Christian L,Liu J,Yien YY,Yu C,Wei S, J Biol Chem. August 1, 2022; 298(8):1083-351X.

Transcription suppression is mediated by the HDAC1-Sin3 complex in Xenopus nucleoplasmic extract., Quaas CE,Lin B,Long DT, J Biol Chem. November 1, 2022; 298(11):1083-351X.

Characteristic tetraspanin expression patterns mark various tissues during early Xenopus development., Kuriyama S,Tanaka M, Dev Growth Differ. February 1, 2023; 65(2):1440-169X.

Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease., Mishra-Gorur K,Barak T,Kaulen LD,Henegariu O,Jin SC,Aguilera SM,Yalbir E,Goles G,Nishimura S,Miyagishima D,Djenoune L,Altinok S,Rai DK,Viviano S,Prendergast A,Zerillo C,Ozcan K,Baran B,Sencar L,Goc N,Yarman Y,Ercan-Sencicek AG,Bilguvar K,Lifton RP,Moliterno J,Louvi A,Yuan S,Deniz E,Brueckner M,Gunel M, Proc Natl Acad Sci U S A. April 18, 2023; 120(16):1091-6490.

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma., Taylor W,Deschamps S,Reboutier D,Paillard L,Méreau A,Audic Y, Cancer Res Commun. December 1, 2022; 2(12):2767-9764.

Exploring the Structural and Functional Diversity among FGF Signals: A Comparative Study of Human, Mouse, and Xenopus FGF Ligands in Embryonic Development and Cancer Pathogenesis., Goutam RS,Kumar V,Lee U,Kim J, Int J Mol Sci. April 20, 2023; 24(8):1422-0067.

TPX2 expression as a negative predictor of gemcitabine efficacy in pancreatic cancer., Guenther M,Surendran SA,Haas M,Heinemann V,von Bergwelt-Baildon M,Engel J,Werner J,Boeck S,Ormanns S, Br J Cancer. July 1, 2023; 129(1):0007-0920.

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer., Pandey A,Cousin H,Horr B,Alfandari D,Alfandari D, Front Cell Dev Biol. January 1, 2023; 11:2296-634X.

Xenopus Ssbp2 is required for embryonic pronephros morphogenesis and terminal differentiation., Cervino AS,Collodel MG,Lopez IA,Roa C,Hochbaum D,Hukriede NA,Cirio MC, Sci Rep. October 4, 2023; 13(1):2045-2322.

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling., Ng VH,Spencer Z,Neitzel LR,Nayak A,Loberg MA,Shen C,Kassel SN,Kroh HK,An Z,Anthony CC,Bryant JM,Lawson A,Goldsmith L,Benchabane H,Hansen AG,Li J,D'Souza S,Lebensohn AM,Rohatgi R,Weiss WA,Weiss VL,Williams C,Hong CC,Robbins DJ,Ahmed Y,Lee E,Lee E, Nat Commun. October 5, 2023; 14(1):2041-1723.

Novel insights into voltage-gated ion channels: Translational breakthroughs in medical oncology., Sakellakis M,Yoon SM,Reet J,Chalkias A, Channels (Austin). December 1, 2024; 18(1):1933-6969.