FIGUTRE 8. Genes repressing or being downregulated during cancer development/progression show varied expression patterns in Xenopus embryos. A, spatial expression patterns were examined with WMISH. Embryos at the same stages as shown in Fig. 6 were used and presented in the same way as in Fig. 6. A, anterior; ad, adenohypophysial placode; ba, branchial arch; cg, cement gland; cgp, cement gland primordium; ep, epidermis; ev, ear vesicle; ey, eye; fb, forebrain; hb, hindbrain; le, lens; mb, midbrain; mhb, midbrain-hindbrain boundary; nc, notochord; nu, neuron; np, neural plate; nt, neural tube; P, posterior; pn, pronephros; pm, paraxial mesoderm; ps, posterior somite; sm, somite; tg, trigeminal nerve. B, summary of the relatedness of gene expression/function in cancer and their expression.
Image published in: Zhang Z et al. (2017)
Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| apc.S | xapc | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate |
| apc.S | xapc | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain hindbrain central nervous system eye branchial arch trigeminal ganglion head pharyngeal region neurogenic placode |
| arid1a.S | LOC108708921 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate neural tube |
| arid1a.S | LOC108708921 | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain hindbrain central nervous system eye branchial arch head pharyngeal region intermediate mesoderm |
| axin1.S | xAxin, axin, fused | X. laevis | Sometime during NF stage 15 to NF stage 20 | |
| axin1.S | xAxin, axin, fused | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| brms1.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | ||
| brms1.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | ||
| casp9.S | xCaspase-9, caspase-9, caspase 9, caspase9, iCasp9 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate |
| casp9.S | xCaspase-9, caspase-9, caspase 9, caspase9, iCasp9 | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain hindbrain head eye pharyngeal region somite central nervous system |
| cdkn1a.L | p16Xic2, p21, cip1 | X. laevis | Sometime during NF stage 15 to NF stage 20 | cement gland primordium ectoderm |
| cdkn1a.L | p16Xic2, p21, cip1 | X. laevis | Sometime during NF stage 26 to NF stage 32 | cement gland somite eye otic vesicle lens placode |
| cdkn1b.S | p16Xic3, kip1, men4, cdkn4, men1b, p27kip1, p17Xic3 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neural plate |
| cdkn1b.S | p16Xic3, kip1, men4, cdkn4, men1b, p27kip1, p17Xic3 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| cdkn2b.L | p15, mts2, tp15, cdk4l, ink4b, p15ink4b | X. laevis | Sometime during NF stage 15 to NF stage 20 | neural plate |
| cdkn2b.L | p15, mts2, tp15, cdk4l, ink4b, p15ink4b | X. laevis | Sometime during NF stage 26 to NF stage 32 | head pharyngeal region |
| chfr.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neural plate neuroectoderm | |
| chfr.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain hindbrain central nervous system head pharyngeal region otic vesicle eye paraxial mesoderm | |
| dlc1.S | rhogap7 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate |
| dlc1.S | rhogap7 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| dmbt1.S | gp340, muclin, hensin, gp-340, glycoprotein 340, salivary agglutinin | X. laevis | Sometime during NF stage 15 to NF stage 20 | ectoderm |
| dmbt1.S | gp340, muclin, hensin, gp-340, glycoprotein 340, salivary agglutinin | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| gas1.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate paraxial mesoderm epidermis | |
| gas1.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain midbrain hindbrain central nervous system somite otic vesicle head | |
| hexim1.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate | |
| hexim1.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | pronephric nephrostome head eye pharyngeal region tail bud otic vesicle brain | |
| hic1.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuron neuroectoderm | |
| hic1.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | trigeminal ganglion notochord | |
| mgmt.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | ||
| mgmt.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | ||
| pbrm1.L | pb1 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate |
| pbrm1.L | pb1 | X. laevis | Sometime during NF stage 26 to NF stage 32 | central nervous system brain eye forebrain midbrain hindbrain pharyngeal region otic vesicle |
| pdcd4.L | h731 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate ectoderm |
| pdcd4.L | h731 | X. laevis | Sometime during NF stage 26 to NF stage 32 | eye lens placode midbrain-hindbrain boundary |
| perp.S | thw, kcp1, pigpc1, krtcap1 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm |
| perp.S | thw, kcp1, pigpc1, krtcap1 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| phlpp1.S | scop, phlpp, plekhe1 | X. laevis | Sometime during NF stage 15 to NF stage 20 | |
| phlpp1.S | scop, phlpp, plekhe1 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| pten.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate ectoderm | |
| pten.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | head brain eye pharyngeal region central nervous system otic vesicle branchial arch forebrain midbrain hindbrain | |
| st13.S | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate | |
| st13.S | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain hindbrain central nervous system eye head pharyngeal region otic vesicle midbrain intermediate mesoderm | |
| tet2.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | ||
| tet2.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain midbrain-hindbrain boundary central nervous system head eye pharyngeal region | |
| tgfbr1.S | aat5, alk5, skr4, alk-5, lds1a, lds2a, tgfr-1, acvrlk4, xTrR-1, TrR-1 | X. laevis | Sometime during NF stage 15 to NF stage 20 | |
| tgfbr1.S | aat5, alk5, skr4, alk-5, lds1a, lds2a, tgfr-1, acvrlk4, xTrR-1, TrR-1 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| tp53.L | p53, Xp53, Trp248, Xrel3, tumor suppressor p53 | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate |
| tp53.L | p53, Xp53, Trp248, Xrel3, tumor suppressor p53 | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain midbrain hindbrain midbrain-hindbrain boundary head eye pharyngeal region central nervous system otic vesicle branchial arch presomitic mesoderm |
| tp73.L | xP73, LOC108696624 | X. laevis | Sometime during NF stage 15 to NF stage 20 | |
| tp73.L | xP73, LOC108696624 | X. laevis | Sometime during NF stage 26 to NF stage 32 | |
| tp53bp2.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | neuroectoderm neural plate cement gland primordium | |
| tp53bp2.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | brain forebrain midbrain midbrain-hindbrain boundary head eye pharyngeal region pronephric mesenchyme otic vesicle central nervous system | |
| txnip.L | X. laevis | Sometime during NF stage 15 to NF stage 20 | ||
| txnip.L | X. laevis | Sometime during NF stage 26 to NF stage 32 | somite ventral mesoderm |
Image source: Published
Permanent Image Page
Printer Friendly View
XB-IMG-158179