Fig.4.L-O,V

Tavares ALP et al. (2021)

Xla Wt + sobp

NF16-18 (in situ hybridization)

Expression Phenotype
increased amount krt12.4.L expression in neuroectoderm decreased amount foxd3.L expression in neural crest decreased amount six1.L expression in lateral preplacodal ectoderm increased amount foxd3.L expression in neuroectoderm

Fig.4.B

Tavares ALP et al. (2021)

Xla Wt + sobp

NF16-18 (RT-PCR)

Expression Phenotype
increased amount krt12.4.L expression in the embryo decreased amount foxd3.L expression in the embryo decreased amount six1.L expression in the embryo

Fig.4.H-K,U

Tavares ALP et al. (2021)

Xla Wt + sobp CRISPR

NF16-18 (in situ hybridization)

Anatomical Phenotype
increased width of neural plate

Expression Phenotype
decreased amount krt12.4.L expression in epidermis decreased amount foxd3.L expression in neural crest decreased amount six1.L expression in lateral preplacodal ectoderm decreased amount sox2.L expression in neural plate

Fig.4.D-G,T

Tavares ALP et al. (2021)

Xla Wt + sobp MO

NF16-18 (in situ hybridization)

Anatomical Phenotype
increased width of neural plate

Expression Phenotype
decreased amount krt12.4.L expression in epidermis decreased amount foxd3.L expression in neural crest decreased amount six1.L expression in lateral preplacodal ectoderm decreased amount sox2.L expression in neural plate

Fig.4.Q-S,X

Tavares ALP et al. (2021)

Xla Wt + sobpR651X

NF16-18 (in situ hybridization)

Expression Phenotype
increased amount krt12.4.L expression in neuroectoderm decreased amount foxd3.L expression in neural crest decreased amount six1.L expression in lateral preplacodal ectoderm

Fig.4.C

Tavares ALP et al. (2021)

Xla Wt + sobpR651X

NF16-18 (RT-PCR)

Expression Phenotype
increased amount krt12.4.L expression in the embryo decreased amount six1.L expression in the embryo

Fig. 3

Virgirinia RP et al. (2021)

Xla Wt + clk1

NF21 (RT-PCR)

Expression Phenotype
increased amount krt12.4.L expression in Keller explant decreased amount sox3.L expression in Keller explant decreased amount zeb2.L expression in Keller explant increased amount ncam1.L expression in Keller explant

Fig. 3

Virgirinia RP et al. (2021)

Xla Wt + clk2

NF21 (RT-PCR)

Expression Phenotype
decreased amount krt12.4.L expression in Keller explant increased amount sox3.L expression in Keller explant increased amount zeb2.L expression in Keller explant

Fig. 3

Virgirinia RP et al. (2021)

Xla Wt + clk3

NF21 (RT-PCR)

Expression Phenotype
decreased amount krt12.4.L expression in Keller explant increased amount ncam1.L expression in Keller explant increased amount sox3.L expression in Keller explant increased amount zeb2.L expression in Keller explant

Fig.6.F

Chen M et al. (2020)

Xla Wt + tmem79 MO

NF16 (in situ hybridization)

Anatomical Phenotype
abnormal neural plate morphology increased size of the epidermis

Expression Phenotype
increased amount krt12.4.L expression in epidermis decreased amount sox2.L expression in neural plate