fig.S4.a

Zhao Y et al. (2016)

Xla Wt + efhc1 MO

NF18 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.S expression in neural plate decreased amount tubb2b.S expression in Rohon-Beard neuron decreased amount egr2.L expression in rhombomere R5

fig.S5.e

Macrì S et al. (2016)

Xla Wt + hmga2 MO

NF17 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.L expression in neuron decreased amount tubb2b.L expression in trigeminal ganglion

Fig.6.a,b

Wylie LA et al. (2015)

Xla Wt + ccna2 + cdk2

NF18-19 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.S expression in neural fold decreased amount hand2.L expression in anterior placodal area decreased amount phox2a.S expression in anterior placodal area decreased amount th.S expression in anterior placodal area

Fig.3.a,b

Wylie LA et al. (2015)

Xla Wt + cdknx MO

NF18-19 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.S expression in neural fold decreased amount hand2.L expression in anterior neural ridge decreased amount th.S expression in anterior neural ridge

Fig.6.a,b

Wylie LA et al. (2015)

Xla Wt + Mmu.ascl1

NF18-19 (in situ hybridization)

Expression Phenotype
increased amount tubb2b.S expression in neural plate border increased amount phox2a.S expression in anterior placodal area increased amount th.S expression in anterior placodal area mislocalised hand2.L expression in anterior placodal area

Fig.7.a,b

Wylie LA et al. (2015)

Xla Wt + Mmu.ascl1

NF18-19 (in situ hybridization)

Expression Phenotype
increased amount tubb2b.S expression in neural plate border mislocalised tubb2b.S expression in neural plate border increased amount hand2.L expression in anterior placodal area increased amount phox2a.S expression in anterior placodal area

Fig.6.a,b

Wylie LA et al. (2015)

Xla Wt + Mmu.ascl1 + ccna2 + cdk2

NF18-19 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.S expression in neural fold increased amount tubb2b.S expression in neural plate border decreased amount hand2.L expression in anterior placodal area decreased amount th.S expression in anterior placodal area

Fig.7.a,b

Wylie LA et al. (2015)

Xla Wt + Mmu.ascl1 + mycn

NF18-19 (in situ hybridization)

Expression Phenotype
increased amount tubb2b.S expression in neural plate border mislocalised tubb2b.S expression in neural plate border decreased amount hand2.L expression in anterior placodal area decreased amount th.S expression in anterior placodal area increased amount phox2a.S expression in anterior placodal area increased amount th.S expression in anterior placodal area

Fig.6.a,b

Wylie LA et al. (2015)

Xla Wt + Mmu.ascl1S62A,S88A,S185A,S189A,S202A,S218A + ccna2 + cdk2

NF18-19 (in situ hybridization)

Expression Phenotype
increased amount tubb2b.S expression in neural plate border decreased amount hand2.L expression in anterior placodal area increased amount phox2a.S expression in anterior placodal area

Fig.7.a,b

Wylie LA et al. (2015)

Xla Wt + mycn

NF18-19 (in situ hybridization)

Expression Phenotype
decreased amount tubb2b.S expression in neural fold decreased amount hand2.L expression in anterior placodal area decreased amount phox2a.S expression in anterior placodal area decreased amount phox2a.S expression in neural fold decreased amount th.S expression in anterior placodal area increased amount phox2a.S expression in anterior placodal area