Fig. 3 (neurula)

Damuth DL et al. (2024)

Xla Wt + Xla.sox21.L

NF15 (RT-PCR)

Expression Phenotype
decreased amount tubb2b.L expression in neuron decreased amount sox2.L expression in neural stem cell

Fig. 3 (neurula)

Damuth DL et al. (2024)

Xla Wt + Xla.sox21.S

NF15 (RT-PCR)

Expression Phenotype
decreased amount tubb2b.L expression in neuron decreased amount sox2.L expression in neural stem cell increased amount myt1.L expression in neural stem cell increased amount neurod1.L expression in neural progenitor cell increased amount six1.L expression in preplacodal ectoderm

Fig. 2E r1c2, r2c2

Wong S et al. (2023)

Xla Wt + Hsa.RAF1

NF28 (in situ hybridization)

Anatomical Phenotype
abnormal spinal cord morphology duplicated tail

Expression Phenotype
mislocalised tubb2b.L expression in ventral side increased amount tbxt.L expression in anterior neural tube mislocalised tbxt.L expression in chordoneural hinge mislocalised tbxt.L expression in tail tip

Fig. S3 r2c5-8

Job F et al. (2023)

Xla Wt + otud3 MO1/2

NF35/36 (in situ hybridization)

Anatomical Phenotype
abnormal eye morphology abnormal head morphology

Expression Phenotype
mislocalised tubb2b.L expression in forebrain

Fig. 4 FGH

Virgirinia RP et al. (2021)

Xtr Wt + clk3 MO

NF37/38 (qPCR)

Expression Phenotype
decreased amount tubb2b expression in whole organism decreased amount ncam1 expression in whole organism

Fig. 2 B

Marquez J et al. (2021)

Xtr wt+ nup205 MO

NF 28

Anatomical Phenotype
abnormally decreased number of cilium in the mucociliary epithelium abnormal multiciliated epidermal cell

Expression Phenotype
decreased amount tubb2b expression in multiciliated epidermal cell

ciliopathy

Fig.6.S1.E

Chen M et al. (2020)

Xla Wt + tmem79 MO

NF16 (in situ hybridization)

Expression Phenotype

decreased amount tubb2b.L expression in neural plate
decreased amount tubb2b.L expression in Rohon-Beard neuron
decreased amount tubb2b.L expression in trigeminal placode
decreased amount ag1.L expression in anterior neural ridge
decreased amount ag1.L expression in cement gland primordium
decreased amount egr2.L expression in rhombomere R3
decreased amount egr2.L expression in rhombomere R5
decreased amount en2.L expression in presumptive midbrain-hindbrain boundary
decreased amount foxg1.L expression in anterior neural ridge

Fig 3 A

Solini GE et al. (2020)

Xla WT + notch1 ICD [bilateral]

NF 18

Anatomical Phenotype
abnormal neural plate absent Rohon-Beard neuron

Expression Phenotype
decreased amount tubb2b.L expression in neural plate

Fig 1. A, G

Solini GE et al. (2020)

Xla WT + notch1 ICD [unilateral]

NF 18

Anatomical Phenotype
abnormally decreased number of Rohon-Beard neuron

Expression Phenotype
decreased amount tubb2b.L expression in neural plate

Fig 1 C I

Solini GE et al. (2020)

Xla WT + notch1 ICD [unilateral]

NF 28

Expression Phenotype
decreased amount tubb2b.L expression in brain decreased amount tubb2b.L expression in spinal cord