Xtr Wt + sox17a MO + sox17b.1/b.2 MO has 13 phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig.1.F

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

NF10.5 (in situ hybridization)
Expression Phenotype
decreased amount hnf1b expression in central endoderm
decreased amount hnf1b expression in endoderm
decreased amount osr1 expression in endoderm
decreased amount osr1 expression in endomesoderm
decreased amount slc5a8.1 expression in involuting marginal zone
decreased amount slc5a8.1 expression in upper blastopore lip
increased amount gdf3 expression in endoderm
increased amount nodal3.1 expression in central endoderm
increased amount nodal3.1 expression in involuting marginal zone
increased amount nodal3.1 expression in ventral marginal zone
increased amount tfap2a expression in marginal zone
Fig.5.Col.2

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

NF10.5 (in situ hybridization)
Expression Phenotype
decreased amount foxa1 expression in endoderm
decreased amount foxa1 expression in ventral marginal zone
decreased amount osr1 expression in endoderm
decreased amount osr1 expression in endomesoderm
decreased amount six1 expression in dorsal endoderm
decreased amount six1 expression in dorsal endomesoderm
increased amount dkk1 expression in central endoderm
increased amount dkk1 expression in endomesoderm
increased amount lhx5 expression in endoderm
Fig.1.S1.D

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

NF10.5 (in situ hybridization)
Expression Phenotype
increased amount wnt8a expression in the animal cap
decreased amount admp expression in dorsal involuting marginal zone
decreased amount dhh expression in blastopore lip
decreased amount gata4 expression in endoderm
decreased amount otx2 expression in dorsal endomesoderm
decreased amount otx2 expression in dorsal involuting marginal zone
increased amount nodal1 expression in endoderm
increased amount nodal1 expression in marginal zone
increased amount nodal1 expression in ventral marginal zone
increased amount wnt8a expression in blastocoel floor
increased amount wnt8a expression in ectoderm
increased amount wnt8a expression in ventral marginal zone
Fig.1.S1.C

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

NF35/36 (in situ hybridization)
Expression Phenotype
decreased amount isl1 expression in eye
decreased amount isl1 expression in intestine
decreased amount isl1 expression in pharyngeal region
decreased amount isl1 expression in pharynx
decreased amount isl1 expression in profundus ganglion
decreased amount nr1h5 expression in liver
decreased amount nr1h5 expression in pharyngeal region
decreased amount osr1 expression in cement gland
decreased amount osr1 expression in intestine
decreased amount osr1 expression in lung
decreased amount osr1 expression in stomach
No Image XB-PHENO-26339

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF10 - RNA-Seq (polyA mRNA)
Expression Phenotype
increased amount tuba1cl.1 expression in the embryo
decreased amount LOC116409809 expression in the embryo
decreased amount tuba1cl.1 expression in the embryo
No Image XB-PHENO-25196

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF10.5 - RNA-Seq (polyA mRNA)
Expression Phenotype
increased amount phyhdla.1 expression in the embryo
increased amount rasl11a expression in the embryo
decreased amount foxa1 expression in the embryo
decreased amount LOC101734776 expression in the embryo
decreased amount LOC108646285 expression in the embryo
No Image XB-PHENO-25197

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF11 (RNA-Seq (polyA mRNA))
Expression Phenotype
increased amount LOC108645249 expression in the embryo
increased amount LOC116408261 expression in the embryo
increased amount LOC116411520 expression in the embryo
increased amount nodal6 expression in the embryo
increased amount rasl11a expression in the embryo
decreased amount adhfe1 expression in the embryo
decreased amount c5h1orf115 expression in the embryo
decreased amount c8a expression in the embryo
decreased amount c8b expression in the embryo
decreased amount cnrip1 expression in the embryo
decreased amount dusp8 expression in the embryo
decreased amount foxa1 expression in the embryo
decreased amount gjb1 expression in the embryo
decreased amount hao1 expression in the embryo
decreased amount igf2 expression in the embryo
decreased amount krt19 expression in the embryo
decreased amount ldlrad3 expression in the embryo
decreased amount LOC100485697 expression in the embryo
decreased amount LOC100495307 expression in the embryo
decreased amount LOC100497256 expression in the embryo
decreased amount LOC100498575 expression in the embryo
decreased amount LOC101732157 expression in the embryo
decreased amount LOC101732615 expression in the embryo
decreased amount LOC101733394 expression in the embryo
decreased amount LOC116406981 expression in the embryo
decreased amount LOC116410271 expression in the embryo
decreased amount ylpm1 expression in the embryo
No Image XB-PHENO-25198

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF12 (RNA-Seq (polyA mRNA))
Expression Phenotype
increased amount atp13a5l.1 expression in the embryo
increased amount cxcl12 expression in the embryo
increased amount esrrgr expression in the embryo
increased amount fgfr1op2 expression in the embryo
increased amount gfi1 expression in the embryo
increased amount gngt1 expression in the embryo
increased amount LOC116407572 expression in the embryo
increased amount LOC116408369 expression in the embryo
increased amount LOC116411987 expression in the embryo
increased amount nodal6 expression in the embryo
increased amount rasl11a expression in the embryo
increased amount satpa expression in the embryo
increased amount socs3 expression in the embryo
increased amount XB5824245 [provisional:rergl] expression in the embryo
decreased amount adhfe1 expression in the embryo
decreased amount aifm3 expression in the embryo
decreased amount anpep expression in the embryo
decreased amount astl2d.4 expression in the embryo
decreased amount atp13a5 expression in the embryo
decreased amount atp13a5l.1 expression in the embryo
decreased amount atp1b1 expression in the embryo
decreased amount c4h3orf18 expression in the embryo
decreased amount c5h1orf115 expression in the embryo
decreased amount c8a expression in the embryo
decreased amount c8b expression in the embryo
decreased amount ca7 expression in the embryo
decreased amount ckmt1b expression in the embryo
decreased amount clcnkb expression in the embryo
decreased amount cnrip1 expression in the embryo
decreased amount cpn1 expression in the embryo
decreased amount cpz expression in the embryo
decreased amount cxcl12 expression in the embryo
decreased amount cyth3 expression in the embryo
decreased amount draxin expression in the embryo
decreased amount dusp8 expression in the embryo
decreased amount enpp3 expression in the embryo
decreased amount fgf10 expression in the embryo
decreased amount foxa1 expression in the embryo
decreased amount ggt1 expression in the embryo
decreased amount gjb1 expression in the embryo
decreased amount gpr82 expression in the embryo
decreased amount h1-6 expression in the embryo
decreased amount hao1 expression in the embryo
decreased amount igf2 expression in the embryo
decreased amount kcnj16 expression in the embryo
decreased amount krt19 expression in the embryo
decreased amount ldlrad3 expression in the embryo
decreased amount lgals2 expression in the embryo
decreased amount LOC100485014 expression in the embryo
decreased amount LOC100493186 expression in the embryo
decreased amount LOC100494786 expression in the embryo
decreased amount LOC100495307 expression in the embryo
decreased amount LOC100497256 expression in the embryo
decreased amount LOC100498388 expression in the embryo
decreased amount LOC100498575 expression in the embryo
decreased amount LOC101730943 expression in the embryo
decreased amount LOC101733394 expression in the embryo
decreased amount LOC101735039 expression in the embryo
decreased amount LOC116406900 expression in the embryo
decreased amount LOC116410271 expression in the embryo
decreased amount mtnr1c expression in the embryo
decreased amount ndrg1 expression in the embryo
decreased amount neurog3 expression in the embryo
decreased amount nt5e expression in the embryo
decreased amount rcan1 expression in the embryo
decreased amount siah2 expression in the embryo
decreased amount slc12a1 expression in the embryo
decreased amount slc3a1 expression in the embryo
decreased amount slc3a2 expression in the embryo
decreased amount slc5a8.1 expression in the embryo
decreased amount st3gal1 expression in the embryo
decreased amount svep1l expression in the embryo
decreased amount wnt11 expression in the embryo
decreased amount XB5824245 [provisional:rergl] expression in the embryo
decreased amount XB5903316 expression in the embryo
decreased amount XB5917669 [provisional] expression in the embryo
No Image XB-PHENO-26342

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF9 (RNA-Seq (polyA mRNA))
No Image XB-PHENO-26397

Mukherjee S et al. (2020) 		Xtr Wt + sox17a MO + sox17b.1/b.2 MO

WE NF9 (RNA-Seq (polyA mRNA))