Images

Sources

Experiment + Assay

Phenotypes

Human Diseases

fig.10.r

Rankin SA et al. (2015)

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX

NF35/36 (in situ hybridization)

Anatomical Phenotype
abnormal development of lung abnormal Wnt signaling pathway abnormally localised lung bud increased size of the lung bud

Expression Phenotype
increased amount nkx2-1.L expression in lung bud mislocalised nkx2-1.L expression in lung bud

fig.10.v

Rankin SA et al. (2015)

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + DEX + PD173074

NF35/36 (in situ hybridization)

Anatomical Phenotype
abnormal development of lung

Expression Phenotype
lung bud that expresses nkx2-1.L increased amount nkx2-1.L expression in lung bud lung bud that expresses nkx2-1.L mislocalised nkx2-1.L expression in lung bud

fig.10.t

Rankin SA et al. (2015)

Xla Wt + Mmu.lef1-Mmu.ctnnb1-GR + wnt2 MO + DEX

NF35/36 (in situ hybridization)

Anatomical Phenotype
abnormal development of lung

Expression Phenotype
lung bud that expresses nkx2-1.L increased amount nkx2-1.L expression in lung bud lung bud that expresses nkx2-1.L