sox3 has 30 expression phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. 2 A

Ismail T et al. (2024)
Xla Wt +PFOS

NF35/36 (in situ hybridization)
Expression Phenotype
increased amount sox3.L expression in forebrain
increased amount sox3.L expression in midbrain-hindbrain boundary
increased amount ldlrap1.L expression in liver primordium
increased amount nkx2-5.L expression in heart
increased amount pax6.L expression in eye
increased amount pax6.L expression in forebrain
increased amount pax6.L expression in hindbrain
increased amount pax6.L expression in midbrain-hindbrain boundary
increased amount pax6.L expression in olfactory region
Fig. 8. A. B

Pandey A et al. (2023)
Xla Wt + adam11 + animal cap explant + dissociation

NF20 (western blot)
Expression Phenotype
decreased amount sox3.L expression in animal cap
increased amount bmp4.L expression in animal cap
Fig. 3. E, F

Pandey A et al. (2023)
Xla Wt + adam11 MO (unilateral)

NF18 (immunohistochemistry)
Anatomical Phenotype
increased size of the cranial neural crest
Expression Phenotype
increased amount sox3.L expression in neural plate
Fig.6 e

Sempou E et al. (2022)
Xtr Wt + K+ (20mM high)

NF10-12 (RNA-Seq)
Expression Phenotype
increased amount sox3 expression in whole organism
increased amount atg13 expression in whole organism
increased amount eomes expression in whole organism
increased amount foxh1 expression in whole organism
increased amount pou5f3.3 expression in whole organism
increased amount rictor expression in whole organism
increased amount smad4 expression in whole organism
increased amount ventx1.2 expression in whole organism
No Image Fig. 3B

Flach H et al. (2022)
Xla Wt + glyphosate [243]

NF13 (in situ hybridization)
Expression Phenotype
decreased amount sox3.L expression in eye primordium
decreased amount pax6.L expression in eye primordium
decreased amount rax.L expression in eye primordium
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk1

NF21 (RT-PCR)
Expression Phenotype
decreased amount sox3.L expression in Keller explant
decreased amount zeb2.L expression in Keller explant
increased amount krt12.4.L expression in Keller explant
increased amount ncam1.L expression in Keller explant
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk2

NF21 (RT-PCR)
Expression Phenotype
increased amount sox3.L expression in Keller explant
decreased amount krt12.4.L expression in Keller explant
increased amount zeb2.L expression in Keller explant
Fig. 3

Virgirinia RP et al. (2021)
Xla Wt + clk3

NF21 (RT-PCR)
Expression Phenotype
increased amount sox3.L expression in Keller explant
decreased amount krt12.4.L expression in Keller explant
increased amount ncam1.L expression in Keller explant
increased amount zeb2.L expression in Keller explant
XB-PHENO-25421

Flach H et al. (2021)
Xla Wt + rbp1 MO1

NF13
Expression Phenotype
mislocalised sox3.L expression in optic field
decreased amount pax6.L expression in optic field
decreased amount rax.L expression in optic field
Fig.3.D

Wang H et al. (2021)
Xla Wt + chd1 + animal cap explant

NF15 (RT-PCR)
Expression Phenotype
increased amount sox3.L expression in the animal cap
increased amount sox2.L expression in the animal cap