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XB-PHENO-16434

Xla WT + rbpj-DBM RNA+ [bilateral], Solini GE et al. (2020)

Experiment + Assay: Xla WT + rbpj-DBM RNA+ [bilateral] + NF 28
Background: Xla.J-strainNXR
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection   notch1.L
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 28 to NF stage 28  
Anatomical Phenotypes: abnormal brain morphology, abnormal embryo morphology
Expression Phenotypes (2):
increased amount tubb2b.L expression in brain
increased amount tubb2b.L expression in spinal cord
Source: Fig 3 K
Article: XB-ART-56609, PubMed