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XB-PHENO-16515

Xtr Wt + Hsa.ZNRF3, Chang LS et al. (2020)

Experiment + Assay: Xtr Wt + Hsa.ZNRF3 + NF 10.5 (in situ hybridization)
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(Hsa.ZNRF3) znrf3
NF stage 2 (2-cell) animal blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 10.5 to NF stage 10.5  
Expression Phenotypes (2):
increased amount gsc expression in dorsal marginal zone
increased amount gsc expression in upper blastopore lip
Source: Fig. 5 supp1, C
Article: XB-ART-56628, PubMed