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XB-PHENO-20178

Xla Wt + pdx1-GR + ptf1a-GR + DEX, Afelik S et al. (2006)

Experiment + Assay: Xla Wt + pdx1-GR + ptf1a-GR + DEX + NF41 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(ptf1a.L-GR) ptf1a.S
ptf1a.L
 NF stage 4 (8-cell) blastomere
mRNA injection Tg(pdx1.L-GR) pdx1.L
pdx1.S
 NF stage 4 (8-cell) blastomere
chemical dexamethasone
NF stage 27 whole organism
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 41  
Expression Phenotypes (6):
mislocalised pdia2.L expression in duodenum
increased amount pdia2.L expression in duodenum
increased amount pdia2.L expression in endoderm
mislocalised pdia2.L expression in endoderm
increased amount pdia2.L expression in foregut
mislocalised pdia2.L expression in foregut
Source: fig.2.b.3
Article: XB-ART-261, PubMed