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XB-PHENO-23627

Xla Wt + Tg(irx1-EnR-hGR) + ChX + Dex, Sullivan CH et al. (2019)

Experiment + Assay: Xla Wt + Tg(irx1-EnR-hGR) + ChX + Dex + NF 16-NF 18 (in situ hybridization)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection Tg(irx1-EnR-hGR) irx1 (Xla)
NF stage 5 (16-cell) animal blastomere
chemical cycloheximide
NF stage 14 embryo
chemical dexamethasone
NF stage 14 embryo
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 16 to NF stage 18  
Expression Phenotypes (1):
mislocalised sox11.L expression in ectoderm
Source: Fig. 9 E
Article: XB-ART-55848, PubMed