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XB-PHENO-24200

Xla Wt + dsp MO, Bharathan NK and Dickinson AJG (2019)

Experiment + Assay: Xla Wt + dsp MO + NF19-20 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection dsp MO1 dsp (Xla)
 NF stage 1 zygote
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 19 to NF stage 20 tuba4a Ab20
Anatomical Phenotypes: abnormal epidermis morphology , abnormally localised microtubule
Expression Phenotypes (1):
mislocalised tuba4b.L expression in epidermis
Human Disease Associations: skin disease
Source: Fig. 6 D
Article: XB-ART-55821, PubMed