Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-24235

Xla Wt + ptpn11N308D, Langdon Y et al. (2012)

Experiment + Assay: Xla Wt + ptpn11N308D + NF33/34 (3D imaging)
Background: Xla.Inbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
DNA injection Tg(ptpn11N308D) ptpn11 (Xla)
 NF stage 1 embryo
Conditions:
Assay Type Assay Stages Antibody
3D imaging NF stage 33 and 34  
Anatomical Phenotypes: abnormal heart morphology, abnormally decreased number of cardiac myocyte
Human Disease Associations: Noonan syndrome
Source: Fig. 2 DJ
Article: XB-ART-44762, PubMed