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XB-PHENO-24273

Xtr Wt + tbx5 MO, Steimle JD et al. (2018)

Experiment + Assay: Xtr Wt + tbx5 MO + NF35/36 (in situ hybridization)
Background: Xtr. IvoryCoast1EXRC
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection tbx5 MO1 tbx5
 NF stage 4 (8-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
in situ hybridization NF stage 35 and 36  
Expression Phenotypes (4):
decreased amount nkx2-1 expression in forebrain
absent nkx2-1 expression in foregut endoderm
absent nkx2-1 expression in lung bud
decreased amount nkx2-1 expression in thyroid primordium
Source: Fig. 2 F
Article: XB-ART-55378, PubMed