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XB-PHENO-25127

Xla Wt + nog + vegt + cyp26a1 + Retinoic acid + CHX + animal cap explant, Gere-Becker MB et al. (2018)

Experiment + Assay: Xla Wt + nog + vegt + cyp26a1 + Retinoic acid + CHX + animal cap explant + animal cap NF12.5 (RNA-Seq (RNA))
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection nog (Xla) nog (Xla)
 NF stage 2 (2-cell) blastomere
mRNA injection vegt (Xla) vegt (Xla)
 NF stage 2 (2-cell) blastomere
mRNA injection cyp26a1 (Xla) cyp26a1 (Xla)
 NF stage 2 (2-cell) blastomere
explant  
NF stage 8 animal cap
chemical Retinoic acid
NF stage 11 animal cap
chemical cycloheximide
NF stage 11 animal cap
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 12.5  
Expression Phenotypes (121):
increased amount ackr3.L expression in the animal cap
increased amount ackr3.S expression in the animal cap
decreased amount actc1.L expression in the animal cap
decreased amount angptl4.L expression in the animal cap
increased amount atoh1.S expression in the animal cap
increased amount barhl2.S expression in the animal cap
increased amount bhlhe40.L expression in the animal cap
increased amount bix1.1.L expression in the animal cap
increased amount bix1.2.L expression in the animal cap
increased amount bix1.3.S expression in the animal cap
increased amount cebpd.S expression in the animal cap
increased amount crh.S expression in the animal cap
decreased amount crygdl.11.L expression in the animal cap
decreased amount crygdl.13.L expression in the animal cap
increased amount cyp26a1.L expression in the animal cap
increased amount cyp26c1.L expression in the animal cap
increased amount cyp26c1.S expression in the animal cap
increased amount dhrs3.L expression in the animal cap
increased amount dhrs3.S expression in the animal cap
increased amount dmrta1.S expression in the animal cap
increased amount dusp6.L expression in the animal cap
increased amount dusp6.S expression in the animal cap
increased amount fam83a.L expression in the animal cap
increased amount foxb1.L expression in the animal cap
increased amount foxh1.L expression in the animal cap
increased amount foxi4.2.L expression in the animal cap
increased amount fzd5.S expression in the animal cap
decreased amount gata3.L expression in the animal cap
increased amount gata3.L expression in the animal cap
decreased amount gata3.S expression in the animal cap
increased amount gata3.S expression in the animal cap
increased amount gbx2.1.L expression in the animal cap
decreased amount gbx2.1.L expression in the animal cap
increased amount gbx2.1.S expression in the animal cap
increased amount gbx2.2.L expression in the animal cap
increased amount gbx2.2.S expression in the animal cap
increased amount hao2.S expression in the animal cap
increased amount hes1.L expression in the animal cap
increased amount hes1.S expression in the animal cap
increased amount hes3.L expression in the animal cap
increased amount hes3.S expression in the animal cap
increased amount hes4.L expression in the animal cap
increased amount hes4.S expression in the animal cap
increased amount hes5.1.L expression in the animal cap
increased amount hes5.2.L expression in the animal cap
increased amount hes5.3.L expression in the animal cap
increased amount hes5.4.L expression in the animal cap
increased amount hes5.4.S expression in the animal cap
increased amount hes5.5.L expression in the animal cap
increased amount hes5.6.L expression in the animal cap
increased amount hes5.6.S expression in the animal cap
increased amount hes5.7.L expression in the animal cap
increased amount hes5.7.S expression in the animal cap
increased amount hes5.8.L expression in the animal cap
increased amount hes5.8.S expression in the animal cap
increased amount hes7.2.L expression in the animal cap
increased amount hes7.2.S expression in the animal cap
increased amount hnf1b.L expression in animal cap
increased amount hoxa1.L expression in the animal cap
increased amount hoxa1.S expression in the animal cap
increased amount hoxa2.L expression in the animal cap
increased amount hoxa2.S expression in the animal cap
increased amount hoxa3.L expression in the animal cap
increased amount hoxa3.S expression in the animal cap
increased amount hoxa4.L expression in the animal cap
increased amount hoxa5.L expression in the animal cap
increased amount hoxa5.S expression in the animal cap
increased amount hoxa6.S expression in the animal cap
increased amount hoxb1.S expression in the animal cap
increased amount hoxb2.S expression in the animal cap
increased amount hoxb4.L expression in the animal cap
increased amount hoxb4.S expression in the animal cap
increased amount hoxd1.S expression in the animal cap
increased amount hoxd4.S expression in the animal cap
increased amount hs3st3a1.L expression in the animal cap
increased amount insm1.S expression in the animal cap
decreased amount lhx1.L expression in animal cap
increased amount lhx1.L expression in animal cap
increased amount mesp2.L expression in the animal cap
increased amount mesp2.S expression in the animal cap
increased amount mespa.L expression in the animal cap
increased amount mespa.S expression in the animal cap
increased amount mespb.L expression in the animal cap
decreased amount mespb.L expression in the animal cap
increased amount neurog2.L expression in the animal cap
increased amount neurog2.S expression in the animal cap
increased amount nkx6-2.L expression in the animal cap
increased amount nodal1.L expression in animal cap
increased amount nodal1.S expression in the animal cap
increased amount not.L expression in the animal cap
increased amount not.S expression in the animal cap
decreased amount nppb.L expression in the animal cap
increased amount prdm14.L expression in the animal cap
increased amount rara.S expression in the animal cap
increased amount rgs2.L expression in the animal cap
increased amount s1pr5.L expression in the animal cap
increased amount s1pr5.S expression in the animal cap
increased amount sema3fl.L expression in the animal cap
increased amount skida1.L expression in the animal cap
increased amount skida1.S expression in the animal cap
decreased amount slc4a1.S expression in the animal cap
increased amount slc4a1.S expression in the animal cap
increased amount sox2.L expression in the animal cap
increased amount sox9.L expression in the animal cap
increased amount tdgf1.2.S expression in the animal cap
increased amount tnk2l.S expression in the animal cap
increased amount trib1.L expression in the animal cap
decreased amount trib1.L expression in the animal cap
increased amount txnip.L expression in the animal cap
increased amount ventx2.1.L expression in the animal cap
decreased amount ventx2.1.L expression in the animal cap
increased amount ventx2.1.S expression in the animal cap
decreased amount ventx2.1.S expression in the animal cap
increased amount ventx2.2.S expression in the animal cap
decreased amount ventx2.2.S expression in the animal cap
increased amount vgll4l.L expression in the animal cap
increased amount zic1.S expression in the animal cap
increased amount zic4.S expression in the animal cap
increased amount znf503.S expression in the animal cap
increased amount znf703.L expression in the animal cap
increased amount znf703.S expression in the animal cap
GEO Series: GSE112718: Xenbase, NCBI
Article: XB-ART-54918, PubMed