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XB-PHENO-25128

Xla Wt + nog + vegt + cyp26a1 + Retinoic acid + animal cap explant, Gere-Becker MB et al. (2018)

Experiment + Assay: Xla Wt + nog + vegt + cyp26a1 + Retinoic acid + animal cap explant + animal cap NF12.5 (RNA-Seq (RNA))
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
mRNA injection nog (Xla) nog (Xla)
 NF stage 2 (2-cell) blastomere
mRNA injection cyp26a1 (Xla) cyp26a1 (Xla)
 NF stage 2 (2-cell) blastomere
mRNA injection vegt (Xla) vegt (Xla)
 NF stage 2 (2-cell) blastomere
explant  
NF stage 8 animal cap
chemical Retinoic acid
NF stage 11 animal cap
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 12.5  
Expression Phenotypes (50):
increased amount atp2a1.S expression in the animal cap
increased amount barhl2.S expression in the animal cap
increased amount bhlhe40.L expression in the animal cap
increased amount cebpd.S expression in the animal cap
decreased amount crygdl.10.L expression in the animal cap
decreased amount crygdl.8.S expression in the animal cap
increased amount cyp26a1.L expression in the animal cap
increased amount cyp26c1.L expression in the animal cap
increased amount cyp26c1.S expression in the animal cap
increased amount dhrs3.L expression in the animal cap
increased amount dhrs3.S expression in the animal cap
increased amount dusp6.L expression in the animal cap
increased amount dusp6.S expression in the animal cap
increased amount gbx2.1.S expression in the animal cap
increased amount gbx2.2.S expression in the animal cap
increased amount hnf1b.L expression in animal cap
increased amount hnf1b.S expression in the animal cap
increased amount hoxa1.L expression in the animal cap
increased amount hoxa1.S expression in the animal cap
increased amount hoxa2.L expression in the animal cap
increased amount hoxa2.S expression in the animal cap
increased amount hoxa3.L expression in the animal cap
increased amount hoxa4.L expression in the animal cap
increased amount hoxa5.L expression in the animal cap
increased amount hoxa5.S expression in the animal cap
increased amount hoxa6.S expression in the animal cap
increased amount hoxb2.S expression in the animal cap
increased amount hoxb4.L expression in the animal cap
increased amount hoxb4.S expression in the animal cap
increased amount hoxd1.S expression in the animal cap
increased amount hoxd4.S expression in the animal cap
increased amount kit.L expression in the animal cap
decreased amount kit.L expression in the animal cap
increased amount klhl30.L expression in the animal cap
increased amount mesp2.L expression in the animal cap
increased amount mespa.L expression in the animal cap
increased amount mespa.S expression in the animal cap
increased amount nkx6-2.L expression in the animal cap
increased amount nodal1.L expression in animal cap
increased amount s1pr5.L expression in the animal cap
increased amount s1pr5.S expression in the animal cap
increased amount sema3fl.L expression in the animal cap
increased amount skida1.S expression in the animal cap
increased amount slc4a1.S expression in the animal cap
decreased amount slc4a1.S expression in the animal cap
increased amount sox9.L expression in the animal cap
increased amount tnk2l.S expression in the animal cap
increased amount txnip.L expression in the animal cap
increased amount znf503.S expression in the animal cap
increased amount znf703.L expression in the animal cap
GEO Series: GSE112718: Xenbase, NCBI
Article: XB-ART-54918, PubMed