Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-PHENO-25206

Xtr WT + dyrk1a CRISPR, Willsey HR et al. (2020)

Experiment + Assay: Xtr WT + dyrk1a CRISPR + brain - NF46
Background: Xtr.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
CRISPR dyrk1a dyrk1a
 NF stage 2 (2-cell) blastomere
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 46  
Expression Phenotypes (57):
decreased amount acta4 expression in the brain
increased amount antxr1 expression in the brain
increased amount atp2a1 expression in the brain
decreased amount atp2a1 expression in the brain
increased amount btn2a2 expression in the brain
increased amount cfd expression in brain
decreased amount ckm expression in the brain
increased amount cldn4 expression in the brain
increased amount cnfn.1 expression in the brain
increased amount dhrs9 expression in the brain
increased amount gatd3ala expression in the brain
increased amount gen1 expression in the brain
increased amount grifin expression in the brain
increased amount hes7.1 expression in the brain
decreased amount hoxb6 expression in the brain
decreased amount hoxb7 expression in the brain
decreased amount hoxc6 expression in brain
increased amount LOC100485381 expression in the brain
increased amount LOC100486357 expression in the brain
increased amount LOC100486969 expression in the brain
increased amount LOC100487369 expression in the brain
increased amount LOC100487732 expression in the brain
increased amount LOC100491571 expression in the brain
increased amount LOC101731222 expression in the brain
increased amount LOC101731845 expression in the brain
increased amount LOC101734526 expression in the brain
increased amount LOC116407953 expression in the brain
increased amount LOC116410826 expression in the brain
increased amount LOC116411664 expression in the brain
decreased amount LOC116411665 expression in the brain
increased amount LOC116412203 expression in the brain
increased amount LOC116412232 expression in the brain
increased amount LOC116412322 expression in the brain
increased amount ly6g6c expression in brain
decreased amount mgc75582 expression in the brain
increased amount mmp8 expression in the brain
increased amount msmb.1 expression in the brain
increased amount msra.2 expression in the brain
decreased amount myh1 expression in the brain
decreased amount myh8 expression in the brain
decreased amount myl1 expression in brain
decreased amount mylpf expression in brain
decreased amount myoz2 expression in the brain
increased amount phyhdla.1 expression in the brain
increased amount phyhdla.2 expression in the brain
increased amount phyhdla.3 expression in the brain
increased amount phyhdlb expression in the brain
increased amount prc1.2 expression in the brain
decreased amount rho expression in the brain
decreased amount smpx expression in the brain
decreased amount tnni2 expression in brain
decreased amount tnnt3 expression in brain
increased amount xa-1 expression in the brain
increased amount XB17329844 [provisional] expression in the brain
increased amount XB5958875 [provisional] expression in the brain
increased amount XB5967085 [provisional] expression in the brain
decreased amount ybx3 expression in the brain
GEO Series: GSE149538: Xenbase, NCBI
Article: XB-ART-57038, PubMed